Exosome adherence and internalization by hepatic stellate cells triggers sphingosine 1-phosphate-dependent migration R Wang, Q Ding, U Yaqoob, TM de Assuncao, VK Verma, P Hirsova, ... Journal of biological chemistry 290 (52), 30684-30696, 2015 | 220 | 2015 |
Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-β signaling in hepatic stellate cells S Cao, U Yaqoob, A Das, U Shergill, K Jagavelu, RC Huebert, C Routray, ... The Journal of clinical investigation 120 (7), 2379-2394, 2010 | 192 | 2010 |
Mechanical stretch increases expression of CXCL1 in liver sinusoidal endothelial cells to recruit neutrophils, generate sinusoidal microthombi, and promote portal hypertension MB Hilscher, T Sehrawat, JP Arab, Z Zeng, J Gao, M Liu, E Kostallari, ... Gastroenterology 157 (1), 193-209. e9, 2019 | 176 | 2019 |
P300 acetyltransferase mediates stiffness-induced activation of hepatic stellate cells into tumor-promoting myofibroblasts C Dou, Z Liu, K Tu, H Zhang, C Chen, U Yaqoob, Y Wang, J Wen, ... Gastroenterology 154 (8), 2209-2221. e14, 2018 | 173 | 2018 |
Neuropilin-1 Stimulates Tumor Growth by Increasing Fibronectin Fibril Assembly in the Tumor Microenvironment U Yaqoob, S Cao, U Shergill, K Jagavelu, Z Geng, M Yin, ... Cancer research 72 (16), 4047-4059, 2012 | 159 | 2012 |
Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype Y Cao, A Szabolcs, SK Dutta, U Yaqoob, K Jagavelu, L Wang, EB Leof, ... Journal of Biological Chemistry 285 (41), 31840-31848, 2010 | 100 | 2010 |
Hepatic stellate cell–derived platelet‐derived growth factor receptor‐alpha‐enriched extracellular vesicles promote liver fibrosis in mice through SHP2 E Kostallari, P Hirsova, A Prasnicka, VK Verma, U Yaqoob, ... Hepatology 68 (1), 333-348, 2018 | 91 | 2018 |
Endothelial P300 promotes portal hypertension and hepatic fibrosis through C‐C motif chemokine ligand 2–mediated angiocrine signaling J Gao, B Wei, M Liu, P Hirsova, TS Sehrawat, S Cao, X Hu, F Xue, ... Hepatology 73 (6), 2468-2483, 2021 | 69 | 2021 |
Enhancer of zeste homologue 2 inhibition attenuates TGF-β dependent hepatic stellate cell activation and liver fibrosis R Martin-Mateos, TM De Assuncao, JP Arab, N Jalan-Sakrikar, U Yaqoob, ... Cellular and Molecular Gastroenterology and Hepatology 7 (1), 197-209, 2019 | 67 | 2019 |
Nitric oxide regulates tumor cell cross-talk with stromal cells in the tumor microenvironment of the liver NK Decker, SS Abdelmoneim, U Yaqoob, H Hendrickson, J Hormes, ... The American journal of pathology 173 (4), 1002-1012, 2008 | 60 | 2008 |
New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids TM De Assuncao, G Lomberk, S Cao, U Yaqoob, A Mathison, ... Journal of Biological Chemistry 289 (22), 15798-15809, 2014 | 59 | 2014 |
HMGB1 recruits hepatic stellate cells and liver endothelial cells to sites of ethanol-induced parenchymal cell injury YS Seo, JH Kwon, U Yaqoob, L Yang, TM De Assuncao, DA Simonetto, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 305 (11 …, 2013 | 51 | 2013 |
Focal adhesion assembly in myofibroblasts fosters a microenvironment that promotes tumor growth N Kang, U Yaqoob, Z Geng, K Bloch, C Liu, T Gomez, D Billadeau, ... The American journal of pathology 177 (4), 1888-1900, 2010 | 45 | 2010 |
FXR promotes endothelial cell motility through coordinated regulation of FAK and MMP-9 A Das, U Yaqoob, D Mehta, VH Shah Arteriosclerosis, thrombosis, and vascular biology 29 (4), 562-570, 2009 | 43 | 2009 |
Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivo T Greuter, U Yaqoob, C Gan, N Jalan-Sakrikar, E Kostallari, J Lu, J Gao, ... Journal of hepatology 77 (3), 723-734, 2022 | 41 | 2022 |
Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12 JP Arab, D Cabrera, TS Sehrawat, N Jalan-Sakrikar, VK Verma, ... Journal of hepatology 73 (1), 149-160, 2020 | 40 | 2020 |
FGF21 promotes endothelial cell angiogenesis through a dynamin-2 and Rab5 dependent pathway U Yaqoob, K Jagavelu, U Shergill, T De Assuncao, S Cao, VH Shah PloS one 9 (5), e98130, 2014 | 34 | 2014 |
Non-canonical role of matrix metalloprotease (MMP) in activation and migration of hepatic stellate cells (HSCs) MS Baig, U Yaqoob, S Cao, U Saqib, VH Shah Life sciences 155, 155-160, 2016 | 28 | 2016 |
GIPC-regulated IGFBP-3 promotes HSC migration in vitro and portal hypertension in vivo through a β1-integrin pathway U Yaqoob, F Luo, T Greuter, NJ Sakrikar, TS Sehrawat, J Lu, X Hu, J Gao, ... Cellular and molecular gastroenterology and hepatology 10 (3), 545-559, 2020 | 24 | 2020 |
Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms MC Drinane, U Yaqoob, H Yu, F Luo, T Greuter, JP Arab, E Kostallari, ... JCI insight 2 (24), 2017 | 24 | 2017 |