Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development HM Kang, SH Ahn, P Choi, YA Ko, SH Han, F Chinga, ASD Park, J Tao, ... Nature medicine 21 (1), 37-46, 2015 | 1213 | 2015 |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, ... Nature communications 7 (1), 10023, 2016 | 484 | 2016 |
Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development YA Ko, D Mohtat, M Suzuki, ASD Park, MC Izquierdo, SY Han, HM Kang, ... Genome biology 14, 1-14, 2013 | 231 | 2013 |
Renal compartment–specific genetic variation analyses identify new pathways in chronic kidney disease C Qiu, S Huang, J Park, YS Park, YA Ko, MJ Seasock, JS Bryer, XX Xu, ... Nature medicine 24 (11), 1721-1731, 2018 | 185 | 2018 |
Genome-wide association studies identify genetic loci associated with albuminuria in diabetes A Teumer, A Tin, R Sorice, M Gorski, NC Yeo, AY Chu, M Li, Y Li, ... Diabetes 65 (3), 803-817, 2016 | 169 | 2016 |
Epigenome-wide association studies identify DNA methylation associated with kidney function AY Chu, A Tin, P Schlosser, YA Ko, C Qiu, C Yao, R Joehanes, ME Grams, ... Nature communications 8 (1), 1286, 2017 | 163 | 2017 |
Polymeric membranes for chiral separation of pharmaceuticals and chemicals A Higuchi, M Tamai, YA Ko, YI Tagawa, YH Wu, BD Freeman, JT Bing, ... Polymer Reviews 50 (2), 113-143, 2010 | 128 | 2010 |
Biomaterials for the feeder-free culture of human embryonic stem cells and induced pluripotent stem cells A Higuchi, QD Ling, YA Ko, Y Chang, A Umezawa Chemical reviews 111 (5), 3021-3035, 2011 | 118 | 2011 |
Genetic-variation-driven gene-expression changes highlight genes with important functions for kidney disease YA Ko, H Yi, C Qiu, S Huang, J Park, N Ledo, A Köttgen, H Li, DJ Rader, ... The American Journal of Human Genetics 100 (6), 940-953, 2017 | 87 | 2017 |
Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection NJ Steers, Y Li, Z Drace, JA D’Addario, C Fischman, L Liu, K Xu, YJ Na, ... New England Journal of Medicine 380 (20), 1918-1928, 2019 | 83 | 2019 |
Kidney cancer is characterized by aberrant methylation of tissue-specific enhancers that are prognostic for overall survival CY Hu, D Mohtat, Y Yu, YA Ko, N Shenoy, S Bhattacharya, MC Izquierdo, ... Clinical Cancer Research 20 (16), 4349-4360, 2014 | 75 | 2014 |
Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease C Gluck, C Qiu, SY Han, M Palmer, J Park, YA Ko, Y Guan, X Sheng, ... Nature communications 10 (1), 2461, 2019 | 69 | 2019 |
Human kidney tubule-specific gene expression based dissection of chronic kidney disease traits P Beckerman, C Qiu, J Park, N Ledo, YA Ko, ASD Park, SY Han, P Choi, ... EBioMedicine 24, 267-276, 2017 | 68 | 2017 |
Epigenetics: a new way to look at kidney diseases P Beckerman, YA Ko, K Susztak Nephrology Dialysis Transplantation 29 (10), 1821-1827, 2014 | 66 | 2014 |
Notch pathway is activated via genetic and epigenetic alterations and is a therapeutic target in clear cell renal cancer TD Bhagat, Y Zou, S Huang, J Park, MB Palmer, C Hu, W Li, N Shenoy, ... Journal of Biological Chemistry 292 (3), 837-846, 2017 | 57 | 2017 |
SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes M Germain, MG Pezzolesi, N Sandholm, AJ McKnight, K Susztak, M Lajer, ... Diabetologia 58, 543-548, 2015 | 56 | 2015 |
Functional genomic annotation of genetic risk loci highlights inflammation and epithelial biology networks in CKD N Ledo, YA Ko, ASD Park, HM Kang, SY Han, P Choi, K Susztak Journal of the American Society of Nephrology 26 (3), 692-714, 2015 | 54 | 2015 |
In Utero Exposure to a High-Fat Diet Programs Hepatic Hypermethylation and Gene Dysregulation and Development of Metabolic Syndrome in Male Mice Y Seki, M Suzuki, X Guo, AS Glenn, PM Vuguin, A Fiallo, Q Du, YA Ko, ... Endocrinology 158 (9), 2860-2872, 2017 | 51 | 2017 |
Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases ST Nurnberg, MA Guerraty, RC Wirka, HS Rao, M Pjanic, S Norton, ... PLoS Genetics 16 (1), e1008538, 2020 | 45 | 2020 |
Kidney disease genetic risk variants alter lysosomal beta-mannosidase (MANBA) expression and disease severity X Gu, H Yang, X Sheng, YA Ko, C Qiu, J Park, S Huang, R Kember, ... Science translational medicine 13 (576), eaaz1458, 2021 | 35 | 2021 |