SPATA2 links CYLD to LUBAC, activates CYLD, and controls LUBAC signaling PR Elliott, D Leske, M Hrdinka, K Bagola, BK Fiil, SH McLaughlin, ... Molecular cell 63 (6), 990-1005, 2016 | 161 | 2016 |
CYLD limits Lys63-and Met1-linked ubiquitin at receptor complexes to regulate innate immune signaling M Hrdinka, BK Fiil, M Zucca, D Leske, K Bagola, M Yabal, PR Elliott, ... Cell reports 14 (12), 2846-2858, 2016 | 160 | 2016 |
The Met1-linked ubiquitin machinery: emerging themes of (De) regulation M Hrdinka, M Gyrd-Hansen Molecular cell 68 (2), 265-280, 2017 | 133 | 2017 |
Inflammatory signaling by NOD-RIPK2 is inhibited by clinically relevant type II kinase inhibitors P Canning, Q Ruan, T Schwerd, M Hrdinka, JL Maki, D Saleh, ... Chemistry & biology 22 (9), 1174-1184, 2015 | 114 | 2015 |
Venetoclax: A new wave in hematooncology J Mihalyova, T Jelinek, K Growkova, M Hrdinka, M Simicek, R Hajek Experimental hematology 61, 10-25, 2018 | 95 | 2018 |
SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling P Draber, I Vonkova, O Stepanek, M Hrdinka, M Kucova, T Skopcova, ... Molecular and cellular biology, 2011 | 68 | 2011 |
Inhibitor of apoptosis proteins in human health and disease M Hrdinka, M Yabal Genes & Immunity 20 (8), 641-650, 2019 | 66 | 2019 |
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK 2 in NOD 2 signaling M Hrdinka, L Schlicher, B Dai, DM Pinkas, JC Bufton, S Picaud, JA Ward, ... The EMBO Journal 37 (17), e99372, 2018 | 66 | 2018 |
Membrane microdomains in immunoreceptor signaling V Horejsi, M Hrdinka FEBS letters 588 (15), 2392-2397, 2014 | 65 | 2014 |
PAG-a multipurpose transmembrane adaptor protein M Hrdinka, V Horejsi Oncogene 33 (41), 4881-4892, 2014 | 60 | 2014 |
May 2006 update in porphobilinogen deaminase gene polymorphisms and mutations causing acute intermittent porphyria. Comparison with the situation in Slavic population M Hrdinka, H Puy, P Martasek Physiological research 55, S119, 2006 | 58 | 2006 |
A new type of membrane raft-like microdomains and their possible involvement in TCR signaling P Otáhal, P Angelisová, M Hrdinka, T Brdička, P Novák, K Drbal, V Hořejší The Journal of Immunology 184 (7), 3689-3696, 2010 | 50 | 2010 |
Intercellular mitochondrial transfer in the tumor microenvironment H Sahinbegovic, T Jelinek, M Hrdinka, JR Bago, M Turi, T Sevcikova, ... Cancers 12 (7), 1787, 2020 | 39 | 2020 |
Synaptonuclear messenger PRR 7 inhibits c‐Jun ubiquitination and regulates NMDA‐mediated excitotoxicity DO Kravchick, A Karpova, M Hrdinka, J Lopez‐Rojas, S Iacobas, ... The EMBO journal 35 (17), 1923-1934, 2016 | 38 | 2016 |
More than 2% of circulating tumor plasma cells defines plasma cell leukemia–like multiple myeloma T Jelinek, R Bezdekova, D Zihala, T Sevcikova, A Anilkumar Sithara, ... Journal of clinical oncology 41 (7), 1383-1392, 2023 | 34 | 2023 |
LST1/A is a myeloid leukocyte-specific transmembrane adaptor protein recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to the plasma membrane P Draber, O Stepanek, M Hrdinka, A Drobek, L Chmatal, L Mala, ... Journal of Biological Chemistry 287 (27), 22812-22821, 2012 | 27 | 2012 |
Acute intermittent porphyria–impact of mutations found in the hydroxymethylbilane synthase gene on biochemical and enzymatic protein properties D Ulbrichova, M Hrdinka, V Saudek, P Martasek The FEBS journal 276 (7), 2106-2115, 2009 | 27 | 2009 |
Systematic analysis of the IL‐17 receptor signalosome reveals a robust regulatory feedback loop H Draberova, S Janusova, D Knizkova, T Semberova, M Pribikova, ... The EMBO journal 39 (17), e104202, 2020 | 19 | 2020 |
PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis M Hrdinka, P Dráber, O Štěpánek, T Ormsby, P Otáhal, P Angelisová, ... Journal of Biological Chemistry 286 (22), 19617-19629, 2011 | 18 | 2011 |
Tuning CARs: recent advances in modulating chimeric antigen receptor (CAR) T cell activity for improved safety, efficacy, and flexibility P Celichowski, M Turi, S Charvátová, D Radhakrishnan, N Feizi, Z Chyra, ... Journal of Translational Medicine 21 (1), 197, 2023 | 16 | 2023 |