| Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation CL Lin, YT Wang, WZ Yang, YY Hsiao, HS Yuan Nucleic acids research 40 (9), 4146-4157, 2012 | 72 | 2012 |
| APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling TC Liu, CT Lin, KC Chang, KW Guo, S Wang, JW Chu, YY Hsiao Nature communications 12 (1), 601, 2021 | 49 | 2021 |
| Structure and function of TatD exonuclease in DNA repair YC Chen, CL Li, YY Hsiao, Y Duh, HS Yuan Nucleic acids research 42 (16), 10776-10785, 2014 | 45 | 2014 |
| How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T–product complexes YY Hsiao, Y Duh, YP Chen, YT Wang, HS Yuan Nucleic acids research 40 (16), 8144-8154, 2012 | 42 | 2012 |
| Structural basis for RNA trimming by RNase T in stable RNA 3′-end maturation YY Hsiao, CC Yang, CL Lin, JLJ Lin, Y Duh, HS Yuan Nature chemical biology 7 (4), 236-243, 2011 | 42 | 2011 |
| Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1 KW Huang, TC Liu, RY Liang, LY Chu, HL Cheng, JW Chu, YY Hsiao PLoS biology 16 (5), e2005653, 2018 | 39 | 2018 |
| Identification of inhibitors for the DEDDh family of exonucleases and a unique inhibition mechanism by Crystal structure analysis of CRN-4 bound with 2-Morpholin-4 … KW Huang, KC Hsu, LY Chu, JM Yang, HS Yuan, YY Hsiao Journal of medicinal chemistry 59 (17), 8019-8029, 2016 | 34 | 2016 |
| Structural insights into DNA repair by RNase T—an exonuclease processing 3′ end of structured DNA in repair pathways YY Hsiao, WH Fang, CC Lee, YP Chen, HS Yuan PLoS biology 12 (3), e1001803, 2014 | 31 | 2014 |
| Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation YY Hsiao, A Nakagawa, Z Shi, S Mitani, D Xue, HS Yuan Molecular and cellular biology 29 (2), 448-457, 2009 | 31 | 2009 |
| The 1.5 Å structure of endo-1, 3-β-glucanase from Streptomyces sioyaensis: evolution of the active-site structure for 1, 3-β-glucan-binding specificity and hydrolysis TY Hong, YY Hsiao, M Meng, THT Li Acta Crystallographica Section D: Biological Crystallography 64 (9), 964-970, 2008 | 28 | 2008 |
| Polarity alteration of a calcium site induces a hydrophobic interaction network and enhances Cel9A endoglucanase thermostability HJ Wang, YY Hsiao, YP Chen, TY Ma, CP Tseng Applied and environmental microbiology 82 (6), 1662-1674, 2016 | 26 | 2016 |
| Structural insights into the duplex DNA processing of TREX2 HL Cheng, CT Lin, KW Huang, S Wang, YT Lin, SI Toh, YY Hsiao Nucleic acids research 46 (22), 12166-12176, 2018 | 21 | 2018 |
| Structural insights into apoptotic DNA degradation by CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans JLJ Lin, A Nakagawa, CL Lin, YY Hsiao, WZ Yang, YT Wang, ... Journal of Biological Chemistry 287 (10), 7110-7120, 2012 | 17 | 2012 |
| Understanding APE1 cellular functions by the structural preference of exonuclease activities TC Liu, KW Guo, JW Chu, YY Hsiao Computational and Structural Biotechnology Journal 19, 3682-3691, 2021 | 15 | 2021 |
| Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation CC Yang, YT Wang, YY Hsiao, LG Doudeva, PH Kuo, SY Chow, HS Yuan RNA 16 (9), 1748-1759, 2010 | 14 | 2010 |
| Functional analysis of Clostridium difficile sortase B reveals key residues for catalytic activity and substrate specificity CY Kang, IH Huang, CC Chou, TY Wu, JC Chang, YY Hsiao, CH Cheng, ... Journal of Biological Chemistry 295 (11), 3734-3745, 2020 | 12 | 2020 |
| Structural insights into substrate recognition by Clostridium difficile sortase JC Yin, CH Fei, YC Lo, YY Hsiao, JC Chang, JC Nix, YY Chang, LW Yang, ... Frontiers in cellular and infection microbiology 6, 160, 2016 | 11 | 2016 |
| Aromatic residues in RN ase T stack with nucleobases to guide the sequence‐specific recognition and cleavage of nucleic acids Y Duh, YY Hsiao, CL Li, JC Huang, HS Yuan Protein Science 24 (12), 1934-1941, 2015 | 11 | 2015 |
| Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids KW Huang, CY Wu, SI Toh, TC Liu, CI Tu, YH Lin, AJ Cheng, YT Kao, ... Nucleic Acids Research 51 (21), 11927-11940, 2023 | 5 | 2023 |
| Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites KW Huang, JW Chen, TY Hua, YY Chu, TY Chiu, JY Liu, CI Tu, KC Hsu, ... JACS Au 1 (12), 2315-2327, 2021 | 5 | 2021 |
Hanna S. YuanAcademia Sinica在 sinica.edu.tw 的电子邮件经过验证
