Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling Y Wang, R Branicky, A Noë, S Hekimi Journal of Cell Biology 217 (6), 1915-1928, 2018 | 1538 | 2018 |
The genetics of caloric restriction in Caenorhabditis elegans B Lakowski, S Hekimi Proceedings of the National Academy of Sciences 95 (22), 13091-13096, 1998 | 1162 | 1998 |
Taking a “good” look at free radicals in the aging process S Hekimi, J Lapointe, Y Wen Trends in cell biology 21 (10), 569-576, 2011 | 760 | 2011 |
Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans J Feng, F Bussière, S Hekimi Developmental cell 1 (5), 633-644, 2001 | 727 | 2001 |
A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans W Yang, S Hekimi PLoS biology 8 (12), e1000556, 2010 | 699 | 2010 |
Determination of life-span in Caenorhabditis elegans by four clock genes B Lakowski, S Hekimi science 272 (5264), 1010-1013, 1996 | 689 | 1996 |
Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans JM Van Raamsdonk, S Hekimi PLoS genetics 5 (2), e1000361, 2009 | 630 | 2009 |
Genetics and the specificity of the aging process S Hekimi, L Guarente Science 299 (5611), 1351-1354, 2003 | 602 | 2003 |
Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing. A Wong, P Boutis, S Hekimi Genetics 139 (3), 1247-1259, 1995 | 511 | 1995 |
Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging A Ben‐Meir, E Burstein, A Borrego‐Alvarez, J Chong, E Wong, ... Aging cell 14 (5), 887-895, 2015 | 422 | 2015 |
The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. elegans C Yee, W Yang, S Hekimi Cell 157 (4), 897-909, 2014 | 404 | 2014 |
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1 JJ Ewbank, TM Barnes, B Lakowski, M Lussier, H Bussey, S Hekimi Science 275 (5302), 980-983, 1997 | 396 | 1997 |
Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice X Liu, N Jiang, B Hughes, E Bigras, E Shoubridge, S Hekimi Genes & development 19 (20), 2424-2434, 2005 | 390 | 2005 |
Superoxide dismutase is dispensable for normal animal lifespan JM Van Raamsdonk, S Hekimi Proceedings of the National Academy of Sciences 109 (15), 5785-5790, 2012 | 387 | 2012 |
CLK‐1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans S Felkai, JJ Ewbank, J Lemieux, JC Labbé, GG Brown, S Hekimi The EMBO journal, 1999 | 330 | 1999 |
When a theory of aging ages badly J Lapointe, S Hekimi Cellular and Molecular Life Sciences 67, 1-8, 2010 | 329 | 2010 |
Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans. TM Barnes, Y Kohara, A Coulson, S Hekimi Genetics 141 (1), 159-179, 1995 | 308 | 1995 |
Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans W Yang, S Hekimi Aging cell 9 (3), 433-447, 2010 | 275 | 2010 |
Understanding ubiquinone Y Wang, S Hekimi Trends in cell biology 26 (5), 367-378, 2016 | 259 | 2016 |
Mitochondrial dysfunction and longevity in animals: untangling the knot Y Wang, S Hekimi Science 350 (6265), 1204-1207, 2015 | 254 | 2015 |