S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate E Jo, MG Sanna, PJ Gonzalez-Cabrera, S Thangada, G Tigyi, ... Chemistry & biology 12 (6), 703-715, 2005 | 292 | 2005 |
Molecular mechanisms of lysophosphatidic acid action G Tigyi, AL Parrill Progress in lipid research 42 (6), 498-526, 2003 | 249 | 2003 |
Reviews in Computational Chemistry 6 KB Lipkowitz, DB Boyd VCH, 1995 | 232 | 1995 |
Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo H Zhang, X Xu, J Gajewiak, R Tsukahara, Y Fujiwara, J Liu, JI Fells, ... Cancer research 69 (13), 5441-5449, 2009 | 218 | 2009 |
GPRC6A mediates the non-genomic effects of steroids M Pi, AL Parrill, LD Quarles Journal of Biological Chemistry 285 (51), 39953-39964, 2010 | 198 | 2010 |
Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate AL Parrill, D Wang, DL Bautista, JR Van Brocklyn, Z Lorincz, DJ Fischer, ... Journal of Biological Chemistry 275 (50), 39379-39384, 2000 | 193 | 2000 |
Short-chain phosphatidates are subtype-selective antagonists of lysophosphatidic acid receptors DJ Fischer, N Nusser, T Virag, K Yokoyama, D Wang, DL Baker, ... Molecular Pharmacology 60 (4), 776-784, 2001 | 188 | 2001 |
Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation JR Williams, AL Khandoga, P Goyal, JI Fells, DH Perygin, W Siess, ... Journal of Biological Chemistry 284 (25), 17304-17319, 2009 | 176 | 2009 |
Solid Phase Synthesis and Secondary Structural Studies of (1→ 5) Amide-Linked Sialooligomers1 L Szabo, BL Smith, KD McReynolds, AL Parrill, ER Morris, J Gervay The Journal of Organic Chemistry 63 (4), 1074-1078, 1998 | 157 | 1998 |
A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors D Wang, Z Lorincz, DL Bautista, K Liliom, G Tigyi, AL Parrill Journal of Biological Chemistry 276 (52), 49213-49220, 2001 | 151 | 2001 |
The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury W Deng, E Shuyu, R Tsukahara, WJ Valentine, G Durgam, V Gududuru, ... Gastroenterology 132 (5), 1834-1851, 2007 | 142 | 2007 |
Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARγ by cyclic phosphatidic acid T Tsukahara, R Tsukahara, Y Fujiwara, J Yue, Y Cheng, H Guo, A Bolen, ... Molecular cell 39 (3), 421-432, 2010 | 139 | 2010 |
Introduction to evolutionary algorithms F Streichert paper to be presented Apr 4, 2002 | 139 | 2002 |
Gold nanorods carrying paclitaxel for photothermal-chemotherapy of cancer F Ren, S Bhana, DD Norman, J Johnson, L Xu, DL Baker, AL Parrill, ... Bioconjugate chemistry 24 (3), 376-386, 2013 | 135 | 2013 |
Molecular basis for lysophosphatidic acid receptor antagonist selectivity VM Sardar, DL Bautista, DJ Fischer, K Yokoyama, N Nusser, T Virag, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2002 | 110 | 2002 |
Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca2+-and voltage-gated … AK Singh, J McMillan, AN Bukiya, B Burton, AL Parrill, AM Dopico Journal of Biological Chemistry 287 (24), 20509-20521, 2012 | 109 | 2012 |
Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells Y Fujiwara, V Sardar, A Tokumura, D Baker, K Murakami-Murofushi, ... Journal of Biological Chemistry 280 (41), 35038-35050, 2005 | 107 | 2005 |
Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor γ T Tsukahara, R Tsukahara, S Yasuda, N Makarova, WJ Valentine, ... Journal of Biological Chemistry 281 (6), 3398-3407, 2006 | 103 | 2006 |
Fatty alcohol phosphates are subtype-selective agonists and antagonists of lysophosphatidic acid receptors T Virag, DB Elrod, K Liliom, VM Sardar, AL Parrill, K Yokoyama, ... Molecular pharmacology 63 (5), 1032-1042, 2003 | 92 | 2003 |
Three-Dimensional Quantitative Structure-Activity Relationship and Comparative Molecular Field Analysis of Dipeptide Hydroxamic Acid Helicobacter pylori Urease … H Mishra, AL Parrill, JS Williamson Antimicrobial agents and chemotherapy 46 (8), 2613-2618, 2002 | 89 | 2002 |