| Predictive compound accumulation rules yield a broad-spectrum antibiotic MF Richter, BS Drown, AP Riley, A Garcia, T Shirai, RL Svec, ... Nature 545 (7654), 299-304, 2017 | 809 | 2017 |
| How many human proteoforms are there? R Aebersold, JN Agar, IJ Amster, MS Baker, CR Bertozzi, ES Boja, ... Nature chemical biology 14 (3), 206-214, 2018 | 806 | 2018 |
| DNA as a target for anticancer compounds: methods to determine the mode of binding and the mechanism of action R Palchaudhuri, PJ Hergenrother Current opinion in biotechnology 18 (6), 497-503, 2007 | 806 | 2007 |
| Targeting RNA with small molecules JR Thomas, PJ Hergenrother Chemical reviews 108 (4), 1171-1224, 2008 | 674 | 2008 |
| Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays FG Kuruvilla, AF Shamji, SM Sternson, PJ Hergenrother, SL Schreiber Nature 416 (6881), 653-657, 2002 | 488 | 2002 |
| Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy KS Putt, GW Chen, JM Pearson, JS Sandhorst, MS Hoagland, JT Kwon, ... Nature chemical biology 2 (10), 543-550, 2006 | 418 | 2006 |
| Glucose conjugation for the specific targeting and treatment of cancer EC Calvaresi, PJ Hergenrother Chemical science 4 (6), 2319-2333, 2013 | 395 | 2013 |
| A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products RW Huigens III, KC Morrison, RW Hicklin, TA Flood Jr, MF Richter, ... Nature chemistry 5 (3), 195-202, 2013 | 335 | 2013 |
| Small-molecule microarrays: covalent attachment and screening of alcohol-containing small molecules on glass slides PJ Hergenrother, KM Depew, SL Schreiber Journal of the American Chemical Society 122 (32), 7849-7850, 2000 | 289 | 2000 |
| Chemical countermeasures for the control of bacterial biofilms: effective compounds and promising targets DJ Musk Jr, PJ Hergenrother Current medicinal chemistry 13 (18), 2163-2177, 2006 | 272 | 2006 |
| Iron salts perturb biofilm formation and disrupt existing biofilms of Pseudomonas aeruginosa DJ Musk, DA Banko, PJ Hergenrother Chemistry & biology 12 (7), 789-796, 2005 | 269 | 2005 |
| Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells C Granchi, S Roy, C Giacomelli, M Macchia, T Tuccinardi, A Martinelli, ... Journal of medicinal chemistry 54 (6), 1599-1612, 2011 | 261 | 2011 |
| Natural products as starting points for the synthesis of complex and diverse compounds KC Morrison, PJ Hergenrother Natural product reports 31 (1), 6-14, 2014 | 223 | 2014 |
| Size-specific ligands for RNA hairpin loops JR Thomas, X Liu, PJ Hergenrother Journal of the American Chemical Society 127 (36), 12434-12435, 2005 | 213 | 2005 |
| The challenge of converting Gram‐positive‐only compounds into broad‐spectrum antibiotics MF Richter, PJ Hergenrother Annals of the New York Academy of Sciences 1435 (1), 18-38, 2019 | 204 | 2019 |
| PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibition QP Peterson, DR Goode, DC West, KN Ramsey, JJY Lee, ... Journal of molecular biology 388 (1), 144-158, 2009 | 194 | 2009 |
| Poly (ADP-ribose) makes a date with death JT Heeres, PJ Hergenrother Current opinion in chemical biology 11 (6), 644-653, 2007 | 192 | 2007 |
| Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis E Llabani, RW Hicklin, HY Lee, SE Motika, LA Crawford, E Weerapana, ... Nature chemistry 11 (6), 521-532, 2019 | 191 | 2019 |
| Identification of the cellular targets of bioactive small organic molecules using affinity reagents BJ Leslie, PJ Hergenrother Chemical Society Reviews 37 (7), 1347-1360, 2008 | 188 | 2008 |
| Procaspase-3 activation as an anti-cancer strategy: Structure− activity relationship of procaspase-activating compound 1 (PAC-1) and Its cellular co-localization with caspase-3 QP Peterson, DC Hsu, DR Goode, CJ Novotny, RK Totten, ... Journal of medicinal chemistry 52 (18), 5721-5731, 2009 | 180 | 2009 |
