| Guidelines for the use and interpretation of assays for monitoring autophagy K DJ Autophagy 12 (1), 1-222, 2016 | 13234* | 2016 |
| PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility X Wang, D Winter, G Ashrafi, J Schlehe, YL Wong, D Selkoe, S Rice, ... Cell 147 (4), 893-906, 2011 | 1242 | 2011 |
| γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2 WT Kimberly, MJ LaVoie, BL Ostaszewski, W Ye, MS Wolfe, DJ Selkoe Proceedings of the National Academy of Sciences 100 (11), 6382-6387, 2003 | 1096 | 2003 |
| Dopamine covalently modifies and functionally inactivates parkin MJ LaVoie, BL Ostaszewski, A Weihofen, MG Schlossmacher, DJ Selkoe Nature medicine 11 (11), 1214-1221, 2005 | 815 | 2005 |
| Dopamine quinone formation and protein modification associated with the striatal neurotoxicity of methamphetamine: evidence against a role for extracellular dopamine MJ LaVoie, TG Hastings Journal of Neuroscience 19 (4), 1484-1491, 1999 | 544 | 1999 |
| Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin G Ashrafi, JS Schlehe, MJ LaVoie, TL Schwarz Journal of Cell Biology 206 (5), 655-670, 2014 | 511 | 2014 |
| The Notch ligands, Jagged and Delta, are sequentially processed by α-secretase and presenilin/γ-secretase and release signaling fragments MJ LaVoie, DJ Selkoe Journal of Biological Chemistry 278 (36), 34427-34437, 2003 | 484 | 2003 |
| Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures M Hakimi, T Selvanantham, E Swinton, RF Padmore, Y Tong, G Kabbach, ... Journal of neural transmission 118, 795-808, 2011 | 311 | 2011 |
| Assembly of the γ-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin MJ LaVoie, PC Fraering, BL Ostaszewski, W Ye, WT Kimberly, MS Wolfe, ... Journal of Biological Chemistry 278 (39), 37213-37222, 2003 | 311 | 2003 |
| Purification and characterization of the human γ-secretase complex PC Fraering, W Ye, JM Strub, G Dolios, MJ LaVoie, BL Ostaszewski, ... Biochemistry 43 (30), 9774-9789, 2004 | 287 | 2004 |
| Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy J Schapansky, JD Nardozzi, F Felizia, MJ LaVoie Human molecular genetics 23 (16), 4201-4214, 2014 | 252 | 2014 |
| Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation Z Berger, KA Smith, MJ LaVoie Biochemistry 49 (26), 5511-5523, 2010 | 244 | 2010 |
| Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity MJ LaVoie, JP Card, TG Hastings Experimental neurology 187 (1), 47-57, 2004 | 235 | 2004 |
| Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease K Venderova, G Kabbach, E Abdel-Messih, Y Zhang, RJ Parks, Y Imai, ... Human molecular genetics 18 (22), 4390-4404, 2009 | 207 | 2009 |
| The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax BN Johnson, AK Berger, GP Cortese, MJ LaVoie Proceedings of the National Academy of Sciences 109 (16), 6283-6288, 2012 | 188 | 2012 |
| Peroxynitrite‐and nitrite‐induced oxidation of dopamine: implications for nitric oxide in dopaminergic cell loss MJ LaVoie, TG Hastings Journal of neurochemistry 73 (6), 2546-2554, 1999 | 185 | 1999 |
| Detergent-dependent dissociation of active γ-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex PC Fraering, MJ LaVoie, W Ye, BL Ostaszewski, WT Kimberly, DJ Selkoe, ... Biochemistry 43 (2), 323-333, 2004 | 175 | 2004 |
| Cell type-specific transcriptomics reveals that mutant huntingtin leads to mitochondrial RNA release and neuronal innate immune activation H Lee, RJ Fenster, SS Pineda, WS Gibbs, S Mohammadi, ... Neuron 107 (5), 891-908. e8, 2020 | 165 | 2020 |
| Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015. 1100356 DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Erratum to: Guidelines for the use and interpretation of assays for …, 2016 | 165 | 2016 |
| γ-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins DM Walsh, JV Fadeeva, MJ LaVoie, K Paliga, S Eggert, WT Kimberly, ... Biochemistry 42 (22), 6664-6673, 2003 | 153 | 2003 |
Dennis SelkoeCo-Director, Ann Romney Center for Neurologic Disases, Brigham and Women's Hospital在 bwh.harvard.edu 的电子邮件经过验证
