Metabolic gatekeeper function of B-lymphoid transcription factors LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ... Nature 542 (7642), 479-483, 2017 | 220 | 2017 |
Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile K Cramer-Morales, M Nieborowska-Skorska, K Scheibner, M Padget, ... Blood, The Journal of the American Society of Hematology 122 (7), 1293-1304, 2013 | 172 | 2013 |
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia Z Chen, S Shojaee, M Buchner, H Geng, JW Lee, L Klemm, B Titz, ... Nature 521 (7552), 357-361, 2015 | 156 | 2015 |
Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia H Geng, C Hurtz, KB Lenz, Z Chen, D Baumjohann, S Thompson, ... Cancer cell 27 (3), 409-425, 2015 | 131 | 2015 |
B-cell-specific diversion of glucose carbon utilization reveals a unique vulnerability in B cell malignancies G Xiao, LN Chan, L Klemm, D Braas, Z Chen, H Geng, QC Zhang, ... Cell 173 (2), 470-484. e18, 2018 | 112 | 2018 |
Simultaneous targeting of PARP1 and RAD52 triggers dual synthetic lethality in BRCA-deficient tumor cells K Sullivan-Reed, E Bolton-Gillespie, Y Dasgupta, S Langer, M Siciliano, ... Cell reports 23 (11), 3127-3136, 2018 | 87 | 2018 |
IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells J Lee, ME Robinson, N Ma, D Artadji, MA Ahmed, G Xiao, T Sadras, ... Nature 588 (7838), 491-497, 2020 | 76 | 2020 |
Signalling input from divergent pathways subverts B cell transformation LN Chan, MA Murakami, ME Robinson, R Caeser, T Sadras, J Lee, ... Nature 583 (7818), 845-851, 2020 | 50 | 2020 |
DACH1 regulates cell cycle progression of myeloid cells through the control of cyclin D, Cdk 4/6 and p21Cip1 JW Lee, HS Kim, S Kim, J Hwang, YH Kim, GY Lim, WJ Sohn, SR Yoon, ... Biochemical and Biophysical Research Communications 420 (1), 91-95, 2012 | 32 | 2012 |
Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses H Contreras-Trujillo, J Eerdeng, S Akre, D Jiang, J Contreras, B Gala, ... Nature communications 12 (1), 6522, 2021 | 29 | 2021 |
Identification of novel retromer complexes in the mouse testis E Kim, JW Lee, DC Baek, SR Lee, MS Kim, SH Kim, K Imakawa, ... Biochemical and biophysical research communications 375 (1), 16-21, 2008 | 26 | 2008 |
Regulation of HOXA9 activity by predominant expression of DACH1 against C/EBPα and GATA-1 in myeloid leukemia with MLL-AF9 JW Lee, HS Kim, J Hwang, YH Kim, GY Lim, WJ Sohn, SR Yoon, JY Kim, ... Biochemical and Biophysical Research Communications 426 (3), 299-305, 2012 | 24 | 2012 |
Processing and subcellular localization of ADAM2 in the Macaca fascicularis testis and sperm E Kim, JW Lee, DC Baek, SR Lee, MS Kim, SH Kim, CS Kim, ZY Ryoo, ... Animal reproduction science 117 (1-2), 155-159, 2010 | 20 | 2010 |
Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1‐EEF1A1 Axis M Li, L Yang, AKN Chan, SP Pokharel, Q Liu, N Mattson, X Xu, WH Chang, ... Advanced Science 10 (17), 2206584, 2023 | 15 | 2023 |
PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis L Pan, C Hong, LN Chan, G Xiao, P Malvi, ME Robinson, H Geng, ... Proceedings of the National Academy of Sciences 118 (7), e2016553118, 2021 | 13 | 2021 |
CD25 (IL2RA) orchestrates negative feedback control and stabilizes oncogenic signaling strength in acute lymphoblastic leukemia JW Lee, Z Chen, H Geng, G Xiao, P Eugene, S Parekh, SM Kornblau, ... Blood 126 (23), 1434, 2015 | 10 | 2015 |
Importance of the porcine ADAM3 disintegrin domain in sperm-egg interaction E Kim, KE Park, JS Kim, DC Baek, JW Lee, SR Lee, MS Kim, SH Kim, ... Journal of Reproduction and Development 55 (2), 156-162, 2009 | 9 | 2009 |
Does IFITM3 link inflammation to tumorigenesis? J Lee BMB reports 55 (12), 602, 2022 | 6 | 2022 |
Ifitm3 (CD225) mediates CD19-dependent survival and proliferation during normal B cell development and in Ph+ ALL J Lee, H Geng, Z Chen, E Park, L Klemm, CC Bailey, M Muschen Blood 122 (21), 2505, 2013 | 5 | 2013 |
IFITM3 (CD225) links the B cell antigen CD19 to PI3K-AKT signaling in human ALL cells JW Lee, H Geng, Z Chen, P Eugene, L Klemm, CC Bailey, M Muschen Blood 126 (23), 1325, 2015 | 4 | 2015 |