Cyclodextrins in the treatment of a mouse model of Niemann-Pick C disease F Camargo, RP Erickson, WS Garver, GS Hossain, PN Carbone, ... Life sciences 70 (2), 131-142, 2001 | 252 | 2001 |
Altered cholesterol metabolism in Niemann-Pick type C1 mouse brains affects mitochondrial function W Yu, JS Gong, M Ko, WS Garver, K Yanagisawa, M Michikawa Journal of biological chemistry 280 (12), 11731-11739, 2005 | 238 | 2005 |
Impaired ABCA1-dependent lipid efflux and hypoalphalipoproteinemia in human Niemann-Pick type C disease HY Choi, B Karten, T Chan, JE Vance, WL Greer, RA Heidenreich, ... Journal of Biological Chemistry 278 (35), 32569-32577, 2003 | 202 | 2003 |
The National Niemann–Pick C1 disease database: report of clinical features and health problems WS Garver, GA Francis, D Jelinek, G Shepherd, J Flynn, G Castro, ... American journal of medical genetics Part A 143 (11), 1204-1211, 2007 | 200 | 2007 |
Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice N Sawamura, JS Gong, WS Garver, RA Heidenreich, H Ninomiya, K Ohno, ... Journal of Biological Chemistry 276 (13), 10314-10319, 2001 | 136 | 2001 |
Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments WS Garver, RA Heidenreich, RP Erickson, MA Thomas, JM Wilson Journal of Lipid Research 41 (5), 673-687, 2000 | 133 | 2000 |
The genetics of childhood obesity and interaction with dietary macronutrients WS Garver, SB Newman, DM Gonzales-Pacheco, JJ Castillo, D Jelinek, ... Genes & nutrition 8, 271-287, 2013 | 119 | 2013 |
The National Niemann-Pick Type C1 Disease Database: correlation of lipid profiles, mutations, and biochemical phenotypes WS Garver, D Jelinek, FJ Meaney, J Flynn, KM Pettit, G Shepherd, ... Journal of lipid research 51 (2), 406-415, 2010 | 115 | 2010 |
Pharmacological and genetic modifications of somatic cholesterol do not substantially alter the course of CNS disease in Niemann–Pick C mice RP Erickson, WS Garver, F Camargo, GS Hossian, RA Heidenreich Journal of inherited metabolic disease 23 (1), 54-62, 2000 | 102 | 2000 |
Niemann-Pick C1 protein regulates cholesterol transport to the trans-Golgi network and plasma membrane caveolae WS Garver, K Krishnan, JR Gallagos, M Michikawa, GA Francis, ... Journal of lipid research 43 (4), 579-589, 2002 | 93 | 2002 |
The Niemann-Pick C proteins and trafficking of cholesterol through the late endosomal/lysosomal system WS Garver, RA Heidenreich Current molecular medicine 2 (5), 485-505, 2002 | 92 | 2002 |
Characterization of liver disease and lipid metabolism in the Niemann‐Pick C1 mouse WS Garver, D Jelinek, JN Oyarzo, J Flynn, M Zuckerman, K Krishnan, ... Journal of cellular biochemistry 101 (2), 498-516, 2007 | 70 | 2007 |
Altered expression of caveolin-1 and increased cholesterol in detergent insoluble membrane fractions from liver in mice with Niemann–Pick disease type C WS Garver, RP Erickson, JM Wilson, TL Colton, GS Hossain, MA Kozloski, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1361 (3), 272-280, 1997 | 70 | 1997 |
Npc1 haploinsufficiency promotes weight gain and metabolic features associated with insulin resistance D Jelinek, V Millward, A Birdi, TP Trouard, RA Heidenreich, WS Garver Human molecular genetics 20 (2), 312-321, 2011 | 59 | 2011 |
Gene-nutrient interactions and susceptibility to human obesity JJ Castillo, RA Orlando, WS Garver Genes & nutrition 12, 1-9, 2017 | 55 | 2017 |
1,8-cineole: An underappreciated anti-inflammatory therapeutic SK Brown, WS Garver, RA Orlando Journal of Biochemical Research Therapeutics 6 (1), 2017 | 52 | 2017 |
The Npc1 mutation causes an altered expression of caveolin-1, annexin II and protein kinases and phosphorylation of caveolin-1 and annexin II in murine livers WS Garver, GS Hossain, MM Winscott, RA Heidenreich Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1453 (2), 193-206, 1999 | 52 | 1999 |
Long‐term survival outcomes of patients with Niemann‐Pick disease type C receiving miglustat treatment: a large retrospective observational study MC Patterson, WS Garver, R Giugliani, J Imrie, H Jahnova, FJ Meaney, ... Journal of Inherited Metabolic Disease 43 (5), 1060-1069, 2020 | 51 | 2020 |
Decreased Npc1 gene dosage in mice is associated with weight gain D Jelinek, RA Heidenreich, RP Erickson, WS Garver Obesity 18 (7), 1457-1459, 2010 | 48 | 2010 |
The extending spectrum of NPC1-related human disorders: From Niemann–Pick C1 disease to obesity A Lamri, M Pigeyre, WS Garver, D Meyre Endocrine Reviews 39 (2), 192-220, 2018 | 45 | 2018 |