Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages Y Zhang, N Chirmule, G Gao, R Qian, M Croyle, B Joshi, J Tazelaar, ... Molecular Therapy 3 (5), 697-707, 2001 | 479 | 2001 |
Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells J Zhu, R Garrett, Y Jung, Y Zhang, N Kim, J Wang, GJ Joe, E Hexner, ... Blood 109 (9), 3706-3712, 2007 | 457 | 2007 |
Host-reactive CD8+ memory stem cells in graft-versus-host disease Y Zhang, G Joe, E Hexner, J Zhu, SG Emerson Nature medicine 11 (12), 1299-1305, 2005 | 457 | 2005 |
Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors MA Schnell, Y Zhang, J Tazelaar, G Gao, QC Yu, R Qian, SJ Chen, ... Molecular Therapy 3 (5), 708-722, 2001 | 445 | 2001 |
Active participation of CCR5+CD8+ T lymphocytes in the pathogenesis of liver injury in graft-versus-host disease M Murai, H Yoneyama, A Harada, Z Yi, C Vestergaard, B Guo, K Suzuki, ... The Journal of clinical investigation 104 (1), 49-57, 1999 | 370 | 1999 |
Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction E Zhao, T Maj, I Kryczek, W Li, K Wu, L Zhao, S Wei, J Crespo, S Wan, ... Nature immunology 17 (1), 95-103, 2016 | 363 | 2016 |
“Stealth” adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung MA Croyle, N Chirmule, Y Zhang, JM Wilson Journal of virology 75 (10), 4792-4801, 2001 | 301 | 2001 |
Preterminal host dendritic cells in irradiated mice prime CD8+ T cell–mediated acute graft-versus-host disease Y Zhang, JP Louboutin, J Zhu, AJ Rivera, SG Emerson The Journal of clinical investigation 109 (10), 1335-1344, 2002 | 276 | 2002 |
Nasal delivery of an adenovirus-based vaccine bypasses pre-existing immunity to the vaccine carrier and improves the immune response in mice MA Croyle, A Patel, KN Tran, M Gray, Y Zhang, JE Strong, H Feldmann, ... PloS one 3 (10), e3548, 2008 | 210 | 2008 |
Targeting CDK9 reactivates epigenetically silenced genes in cancer H Zhang, S Pandey, M Travers, H Sun, G Morton, J Madzo, W Chung, ... Cell 175 (5), 1244-1258. e26, 2018 | 207 | 2018 |
Erythropoietin gene therapy leads to autoimmune anemia in macaques G Gao, C Lebherz, DJ Weiner, R Grant, R Calcedo, B McCullough, ... Blood 103 (9), 3300-3302, 2004 | 202 | 2004 |
PEGylation of E1-deleted adenovirus vectors allows significant gene expression on readministration to liver MA Croyle, N Chirmule, Y Zhang, JM Wilson Human gene therapy 13 (15), 1887-1900, 2002 | 202 | 2002 |
Tumor necrosis factor (TNF) is a physiologic regulator of hematopoietic progenitor cells: increase of early hematopoietic progenitor cells in TNF receptor p55-deficient mice in … Y Zhang, A Harada, H Bluethmann, JB Wang, S Nakao, N Mukaida, ... | 197 | 1995 |
Pivotal role of TARC, a CC chemokine, in bacteria-induced fulminant hepatic failure in mice. H Yoneyama, A Harada, T Imai, M Baba, O Yoshie, Y Zhang, H Higashi, ... The Journal of clinical investigation 102 (11), 1933-1941, 1998 | 189 | 1998 |
Immune parameters correlate with protection against ebola virus infection in rodents and nonhuman primates G Wong, JS Richardson, S Pillet, A Patel, X Qiu, J Alimonti, J Hogan, ... Science translational medicine 4 (158), 158ra146-158ra146, 2012 | 182 | 2012 |
APCs in the liver and spleen recruit activated allogeneic CD8+ T cells to elicit hepatic graft-versus-host disease Y Zhang, WD Shlomchik, G Joe, JP Louboutin, J Zhu, A Rivera, ... The Journal of Immunology 169 (12), 7111-7118, 2002 | 177 | 2002 |
Pivotal role for glycogen synthase kinase–3 in hematopoietic stem cell homeostasis in mice J Huang, Y Zhang, A Bersenev, WT O’Brien, W Tong, SG Emerson, ... The Journal of clinical investigation 119 (12), 3519-3529, 2009 | 170 | 2009 |
Alloreactive memory T cells are responsible for the persistence of graft-versus-host disease Y Zhang, G Joe, E Hexner, J Zhu, SG Emerson The Journal of Immunology 174 (5), 3051-3058, 2005 | 164 | 2005 |
Mesenchymal stem cells alleviate bacteria‐induced liver injury in mice by inducing regulatory dendritic cells Y Zhang, W Cai, Q Huang, Y Gu, Y Shi, J Huang, F Zhao, Q Liu, X Wei, ... Hepatology 59 (2), 671-682, 2014 | 160 | 2014 |
CD40 ligand-dependent activation of cytotoxic T lymphocytes by adeno-associated virus vectors in vivo: role of immature dendritic cells YI Zhang, N Chirmule, G Gao, J Wilson Journal of virology 74 (17), 8003-8010, 2000 | 147 | 2000 |