The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain WM Babinchak, R Haider, BK Dumm, P Sarkar, K Surewicz, JK Choi, ... Journal of Biological Chemistry 294 (16), 6306-6317, 2019 | 292 | 2019 |
Mammalian prions generated from bacterially expressed prion protein in the absence of any mammalian cofactors JI Kim, I Cali, K Surewicz, Q Kong, GJ Raymond, R Atarashi, B Race, ... Journal of Biological Chemistry 285 (19), 14083-14087, 2010 | 269 | 2010 |
Molecular conformation and dynamics of the Y145Stop variant of human prion protein in amyloid fibrils JJ Helmus, K Surewicz, PS Nadaud, WK Surewicz, CP Jaroniec Proceedings of the National Academy of Sciences 105 (17), 6284-6289, 2008 | 210 | 2008 |
Liquid–liquid phase separation of tau protein: the crucial role of electrostatic interactions S Boyko, XU Qi, TH Chen, K Surewicz, WK Surewicz Journal of Biological Chemistry 294 (29), 11054-11059, 2019 | 204 | 2019 |
Rapidly progressive Alzheimer’s disease features distinct structures of amyloid-β ML Cohen, C Kim, T Haldiman, M ElHag, P Mehndiratta, T Pichet, ... Brain 138 (4), 1009-1022, 2015 | 201 | 2015 |
The effect of disease-associated mutations on the folding pathway of human prion protein AC Apetri, K Surewicz, WK Surewicz Journal of Biological Chemistry 279 (17), 18008-18014, 2004 | 186 | 2004 |
Molecular basis of barriers for interspecies transmissibility of mammalian prions DL Vanik, KA Surewicz, WK Surewicz Molecular cell 14 (1), 139-145, 2004 | 178 | 2004 |
Conformational flexibility of Y145Stop human prion protein amyloid fibrils probed by solid-state nuclear magnetic resonance spectroscopy JJ Helmus, K Surewicz, WK Surewicz, CP Jaroniec Journal of the American Chemical Society 132 (7), 2393-2403, 2010 | 150 | 2010 |
Conformational diversity in prion protein variants influences intermolecular β‐sheet formation S Lee, L Antony, R Hartmann, KJ Knaus, K Surewicz, WK Surewicz, ... The EMBO journal 29 (1), 251-262, 2010 | 150 | 2010 |
Nucleation-dependent conformational conversion of the Y145Stop variant of human prion protein: structural clues for prion propagation B Kundu, NR Maiti, EM Jones, KA Surewicz, DL Vanik, WK Surewicz Proceedings of the National Academy of Sciences 100 (21), 12069-12074, 2003 | 130 | 2003 |
Soluble prion protein inhibits amyloid-β (Aβ) fibrillization and toxicity K Nieznanski, JK Choi, S Chen, K Surewicz, WK Surewicz Journal of Biological Chemistry 287 (40), 33104-33108, 2012 | 103 | 2012 |
Mechanisms of I Ks suppression in LQT1 mutants L Bianchi, SG Priori, C Napolitano, KA Surewicz, AT Dennis, M Memmi, ... American Journal of Physiology-Heart and Circulatory Physiology 279 (6 …, 2000 | 100 | 2000 |
Antimicrobial activity of human prion protein is mediated by its N-terminal region M Pasupuleti, M Roupe, V Rydengård, K Surewicz, WK Surewicz, ... PLoS One 4 (10), e7358, 2009 | 98 | 2009 |
Regulatory mechanisms of tau protein fibrillation under the conditions of liquid–liquid phase separation S Boyko, K Surewicz, WK Surewicz Proceedings of the National Academy of Sciences 117 (50), 31882-31890, 2020 | 96 | 2020 |
Amyloid fibrils from the N-terminal prion protein fragment are infectious JK Choi, I Cali, K Surewicz, Q Kong, P Gambetti, WK Surewicz Proceedings of the National Academy of Sciences 113 (48), 13851-13856, 2016 | 91 | 2016 |
Zinc promotes liquid–liquid phase separation of tau protein V Singh, L Xu, S Boyko, K Surewicz, WK Surewicz Journal of Biological Chemistry 295 (18), 5850-5856, 2020 | 90 | 2020 |
Small Protease Sensitive Oligomers of PrPSc in Distinct Human Prions Determine Conversion Rate of PrPC C Kim, T Haldiman, K Surewicz, Y Cohen, W Chen, J Blevins, MS Sy, ... Public Library of Science 8 (8), e1002835, 2012 | 88 | 2012 |
Endometriotic lesions synthesize and secrete a haptoglobin-like protein KL Sharpe-Timms, M Piva, EA Ricke, K Surewicz, YL Zhang, RL Zimmer Biology of reproduction 58 (4), 988-994, 1998 | 83 | 1998 |
Intermolecular alignment in Y145Stop human prion protein amyloid fibrils probed by solid-state NMR spectroscopy JJ Helmus, K Surewicz, MI Apostol, WK Surewicz, CP Jaroniec Journal of the American Chemical Society 133 (35), 13934-13937, 2011 | 75 | 2011 |
Partial purification and amino acid sequence analysis of endometriosis protein-II (ENDO-II) reveals homology with tissue inhibitor of metalloproteinases-1 (TIMP-1) KL Sharpe-Timms, LL Penney, RL Zimmer, JA Wright, Y Zhang, ... The Journal of Clinical Endocrinology & Metabolism 80 (12), 3784-3787, 1995 | 75 | 1995 |