The synaptic vesicle release machinery J Rizo, J Xu Annual review of biophysics 44 (1), 339-367, 2015 | 369 | 2015 |
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth L Wang, J Chang, D Varghese, M Dellinger, S Kumar, AM Best, J Ruiz, ... Nature communications 4 (1), 2035, 2013 | 320 | 2013 |
Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution KD Brewer, T Bacaj, A Cavalli, C Camilloni, JD Swarbrick, J Liu, A Zhou, ... Nature structural & molecular biology 22 (7), 555-564, 2015 | 153 | 2015 |
Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity M Xue, TK Craig, J Xu, HT Chao, J Rizo, C Rosenmund Nature structural & molecular biology 17 (5), 568-575, 2010 | 148 | 2010 |
Functional synergy between the Munc13 C-terminal C1 and C2 domains X Liu, AB Seven, M Camacho, V Esser, J Xu, T Trimbuch, B Quade, L Su, ... elife 5, e13696, 2016 | 117 | 2016 |
Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN J Xu, M Camacho, Y Xu, V Esser, X Liu, T Trimbuch, YZ Pan, C Ma, ... Elife 6, e22567, 2017 | 116 | 2017 |
Membrane bridging by Munc13-1 is crucial for neurotransmitter release B Quade, M Camacho, X Zhao, M Orlando, T Trimbuch, J Xu, W Li, ... Elife 8, e42806, 2019 | 96 | 2019 |
Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion E Sitarska, J Xu, S Park, X Liu, B Quade, K Stepien, K Sugita, ... Elife 6, e24278, 2017 | 83 | 2017 |
Re-examining how complexin inhibits neurotransmitter release T Trimbuch, J Xu, D Flaherty, DR Tomchick, J Rizo, C Rosenmund Elife 3, e02391, 2014 | 82 | 2014 |
Solution structure of Urm1 and its implications for the origin of protein modifiers J Xu, J Zhang, L Wang, J Zhou, H Huang, J Wu, Y Zhong, Y Shi Proceedings of the National Academy of Sciences 103 (31), 11625-11630, 2006 | 82 | 2006 |
Multiple factors maintain assembled trans-SNARE complexes in the presence of NSF and αSNAP EA Prinslow, KP Stepien, YZ Pan, J Xu, J Rizo Elife 8, e38880, 2019 | 67 | 2019 |
Subtle interplay between synaptotagmin and complexin binding to the SNARE complex J Xu, KD Brewer, R Perez-Castillejos, J Rizo Journal of molecular biology 425 (18), 3461-3475, 2013 | 60 | 2013 |
Structure and Ca2+-binding properties of the tandem C2 domains of E-Syt2 J Xu, T Bacaj, A Zhou, DR Tomchick, TC Südhof, J Rizo Structure 22 (2), 269-280, 2014 | 50 | 2014 |
SNARE assembly enlightened by cryo-EM structures of a synaptobrevin–Munc18-1–syntaxin-1 complex KP Stepien, J Xu, X Zhang, XC Bai, J Rizo Science advances 8 (25), eabo5272, 2022 | 47 | 2022 |
UNC-18 and tomosyn antagonistically control synaptic vesicle priming downstream of UNC-13 in Caenorhabditis elegans S Park, NR Bin, B Yu, R Wong, E Sitarska, K Sugita, K Ma, J Xu, CW Tien, ... Journal of Neuroscience 37 (36), 8797-8815, 2017 | 42 | 2017 |
Control of neurotransmitter release by two distinct membrane-binding faces of the Munc13-1 C1C2B region M Camacho, B Quade, T Trimbuch, J Xu, L Sari, J Rizo, C Rosenmund Elife 10, e72030, 2021 | 31 | 2021 |
Simultaneous lipid and content mixing assays for in vitro reconstitution studies of synaptic vesicle fusion X Liu, AB Seven, J Xu, V Esser, L Su, C Ma, J Rizo Nature protocols 12 (9), 2014-2028, 2017 | 29 | 2017 |
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat Commun. 2013; 4: 2035 L Wang, J Chang, D Varghese, M Dellinger, S Kumar, AM Best, J Ruiz, ... Epub 2013/06/26. doi: 10.1038/ncomms3035. PubMed PMID: 23792809, 0 | 8 | |
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat Commun 4: 2035 L Wang, J Chang, D Varghese, M Dellinger, S Kumar, AM Best, J Ruiz, ... | 7 | 2013 |
Synaptic vesicle fusion without SNARE transmembrane regions J Rizo, J Xu Developmental cell 27 (2), 124-126, 2013 | 6 | 2013 |