Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR M Haeussler, K Schönig, H Eckert, A Eschstruth, J Mianné, JB Renaud, ... Genome biology 17, 1-12, 2016 | 1654 | 2016 |
The potential for β-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse … MM Mocanu, A Nissen, K Eckermann, I Khlistunova, J Biernat, D Drexler, ... Journal of Neuroscience 28 (3), 737-748, 2008 | 347 | 2008 |
An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice M Traykova-Brauch, K Schönig, O Greiner, T Miloud, A Jauch, M Bode, ... Nature medicine 14 (9), 979-984, 2008 | 297 | 2008 |
Stringent doxycycline dependent control of CRE recombinase in vivo K Schönig, F Schwenk, K Rajewsky, H Bujard Nucleic acids research 30 (23), e134-e134, 2002 | 266 | 2002 |
Conditional tetracycline-regulated expression of TGF-β1 in liver of transgenic mice leads to reversible intermediary fibrosis E Ueberham, R Löw, U Ueberham, K Schönig, H Bujard, R Gebhardt Hepatology 37 (5), 1067-1078, 2003 | 220 | 2003 |
The β-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy K Eckermann, MM Mocanu, I Khlistunova, J Biernat, A Nissen, A Hofmann, ... Journal of Biological Chemistry 282 (43), 31755-31765, 2007 | 206 | 2007 |
Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III J Björkqvist, S de Maat, U Lewandrowski, A Di Gennaro, C Oschatz, ... The Journal of clinical investigation 125 (8), 3132-3146, 2015 | 187 | 2015 |
A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats S Nuber, F Harmuth, Z Kohl, A Adame, M Trejo, K Schönig, ... Brain 136 (2), 412-432, 2013 | 161 | 2013 |
Losing control: excessive alcohol seeking after selective inactivation of cue-responsive neurons in the infralimbic cortex S Pfarr, MW Meinhardt, ML Klee, AC Hansson, V Vengeliene, K Schönig, ... Journal of Neuroscience 35 (30), 10750-10761, 2015 | 144 | 2015 |
Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice L Viatte, G Nicolas, DQ Lou, M Bennoun, JC Lesbordes-Brion, ... Blood 107 (7), 2952-2958, 2006 | 116 | 2006 |
Long‐term, noninvasive imaging of regulated gene expression in living mice MT Hasan, K Schönig, S Berger, W Graewe, H Bujard Genesis 29 (3), 116-122, 2001 | 106 | 2001 |
A genetic switch for epilepsy in adult mice HE Krestel, DR Shimshek, V Jensen, T Nevian, J Kim, Y Geng, T Bast, ... Journal of Neuroscience 24 (46), 10568-10578, 2004 | 92 | 2004 |
Inducible expression of coding and inhibitory RNAs from retargetable genomic loci I Weidenfeld, M Gossen, R Löw, D Kentner, S Berger, D Görlich, ... Nucleic acids research 37 (7), e50-e50, 2009 | 90 | 2009 |
Generating conditional mouse mutants via tetracycline-controlled gene expression K Schönig, H Bujard Transgenic Mouse: Methods and Protocols, 69-104, 2002 | 81 | 2002 |
Synthetic microRNA-mediated downregulation of Nogo-A in transgenic rats reveals its role as regulator of synaptic plasticity and cognitive function B Tews, K Schönig, ME Arzt, S Clementi, MS Rioult-Pedotti, A Zemmar, ... Proceedings of the National Academy of Sciences 110 (16), 6583-6588, 2013 | 78 | 2013 |
Liver-specific expression of interferon γ following adenoviral gene transfer controls hepatitis B virus replication in mice J Dumortier, K Schönig, H Oberwinkler, R Löw, T Giese, H Bujard, ... Gene therapy 12 (8), 668-677, 2005 | 62 | 2005 |
Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism MW Meinhardt, S Pfarr, G Fouquet, C Rohleder, ML Meinhardt, ... Science Advances 7 (47), eabh2399, 2021 | 60 | 2021 |
Retrocochlear function of the peripheral deafness gene Cacna1d SV Satheesh, K Kunert, L Rüttiger, A Zuccotti, K Schönig, E Friauf, ... Human molecular genetics 21 (17), 3896-3909, 2012 | 55 | 2012 |
Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo J Wilkinson IV, X Di, K Schönig, JL Buss, ND Kock, JM Cline, TL Saunders, ... Biochemical Journal 395 (3), 501-507, 2006 | 55 | 2006 |
Srgap3–/– mice present a neurodevelopmental disorder with schizophrenia‐related intermediate phenotypes R Waltereit, U Leimer, OBU Halbach, J Panke, SM Hölter, L Garrett, ... The FASEB Journal 26 (11), 4418-4428, 2012 | 54 | 2012 |