S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy S Rizza, S Cardaci, C Montagna, G Di Giacomo, D De Zio, M Bordi, ... Proceedings of the National Academy of Sciences 115 (15), E3388-E3397, 2018 | 151 | 2018 |
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue M Rosina, V Ceci, R Turchi, C Li, N Borcherding, F Sciarretta, ... Cell metabolism 34 (4), 533-548. e12, 2022 | 114 | 2022 |
AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity E Maiani, G Milletti, F Nazio, SG Holdgaard, J Bartkova, S Rizza, ... Nature 592 (7856), 799-803, 2021 | 94 | 2021 |
S-nitrosylation of the mitochondrial chaperone TRAP1 sensitizes hepatocellular carcinoma cells to inhibitors of succinate dehydrogenase S Rizza, C Montagna, S Cardaci, E Maiani, G Di Giacomo, ... Cancer research 76 (14), 4170-4182, 2016 | 70 | 2016 |
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1 S Cardaci, S Rizza, G Filomeni, R Bernardini, F Bertocchi, M Mattei, ... Cancer research 72 (17), 4526-4536, 2012 | 55 | 2012 |
Chronicles of a reductase: Biochemistry, genetics and physio-pathological role of GSNOR S Rizza, G Filomeni Free Radical Biology and Medicine, 2017 | 51 | 2017 |
S-nitrosoglutathione reductase deficiency-induced S-nitrosylation results in neuromuscular dysfunction C Montagna, G Di Giacomo, S Rizza, S Cardaci, E Ferraro, P Grumati, ... Antioxidants & redox signaling 21 (4), 570-587, 2014 | 48 | 2014 |
Loss of Ambra1 promotes melanoma growth and invasion L Di Leo, V Bodemeyer, FM Bosisio, G Claps, M Carretta, S Rizza, ... Nature Communications 12 (1), 1-17, 2021 | 42 | 2021 |
To eat, or NOt to eat: S‐nitrosylation signaling in autophagy C Montagna, S Rizza, E Maiani, L Piredda, G Filomeni, F Cecconi The FEBS journal 283 (21), 3857-3869, 2016 | 39 | 2016 |
Established principles and emerging concepts on the interplay between mitochondrial physiology and S-(De) nitrosylation: implications in cancer and neurodegeneration G Di Giacomo, S Rizza, C Montagna, G Filomeni International journal of cell biology 2012, 2012 | 37 | 2012 |
Redox activation of ATM enhances GSNOR translation to sustain mitophagy and tolerance to oxidative stress C Cirotti, S Rizza, P Giglio, N Poerio, MF Allega, G Claps, C Pecorari, ... EMBO reports 22 (1), e50500, 2021 | 35 | 2021 |
Use of computational biochemistry for elucidating molecular mechanisms of nitric oxide synthase E Bignon, S Rizza, G Filomeni, E Papaleo Computational and structural biotechnology journal 17, 415-429, 2019 | 30 | 2019 |
Denitrosylate and live longer: how ADH5/GSNOR links mitophagy to aging S Rizza, G Filomeni Autophagy 14 (7), 1285-1287, 2018 | 25 | 2018 |
When S-Nitrosylation Gets to Mitochondria: From Signaling to Age-Related Diseases C Montagna, C Cirotti, S Rizza, G Filomeni Antioxidants & Redox Signaling 32 (12), 884-905, 2020 | 22 | 2020 |
Redox proteome analysis of auranofin exposed ovarian cancer cells (A2780) G Chiappetta, T Gamberi, F Faienza, X Limaj, S Rizza, L Messori, ... Redox Biology, 102294, 2022 | 21 | 2022 |
S-nitrosylation affects TRAP1 structure and ATPase activity and modulates cell response to apoptotic stimuli F Faienza, M Lambrughi, S Rizza, C Pecorari, P Giglio, JS Viloria, ... Biochemical pharmacology 176, 113869, 2020 | 20 | 2020 |
Role, targets and regulation of (de) nitrosylation in malignancy. S Rizza, G Filomeni Frontiers in Oncology 8, 334, 2018 | 19 | 2018 |
Exploiting S-nitrosylation for cancer therapy: facts and perspectives S Rizza, G Filomeni Biochemical Journal 477 (19), 3649-3672, 2020 | 17 | 2020 |
S-Nitrosoglutathione Reductase Plays Opposite Roles in SH-SY5Y Models of Parkinson’s Disease and Amyotrophic Lateral Sclerosis S Rizza, C Cirotti, C Montagna, S Cardaci, C Consales, M Cozzolino, ... Mediators of inflammation 2015, 2015 | 17 | 2015 |
Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma S Rizza, L Di Leo, S Mandatori, D De Zio, G Filomeni Biochemical pharmacology 176, 113885, 2020 | 16 | 2020 |