Premature aging in mice deficient in DNA repair and transcription J De Boer, JO Andressoo, J de Wit, J Huijmans, RB Beems, H van Steeg, ... Science 296 (5571), 1276-1279, 2002 | 627 | 2002 |
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo P Lindholm, MH Voutilainen, J Laurén, J Peränen, VM Leppänen, ... Nature 448 (7149), 73-77, 2007 | 541 | 2007 |
Biology of GDNF and its receptors—relevance for disorders of the central nervous system CF Ibáñez, JO Andressoo Neurobiology of disease 97, 80-89, 2017 | 238 | 2017 |
MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain P Lindholm, J Peränen, JO Andressoo, N Kalkkinen, Z Kokaia, O Lindvall, ... Molecular and Cellular Neuroscience 39 (3), 356-371, 2008 | 213 | 2008 |
MANF is indispensable for the proliferation and survival of pancreatic β cells M Lindahl, T Danilova, E Palm, P Lindholm, V Voikar, E Hakonen, ... Cell reports 7 (2), 366-375, 2014 | 212 | 2014 |
miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF K Varendi, A Kumar, MA Härma, JO Andressoo Cellular and molecular life sciences 71, 4443-4456, 2014 | 173 | 2014 |
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice H de Waard, J de Wit, TGMF Gorgels, G van den Aardweg, JO Andressoo, ... DNA repair 2 (1), 13-25, 2003 | 150 | 2003 |
GDNF overexpression from the native locus reveals its role in the nigrostriatal dopaminergic system function A Kumar, J Kopra, K Varendi, LL Porokuokka, A Panhelainen, S Kuure, ... PLoS genetics 11 (12), e1005710, 2015 | 125 | 2015 |
Different Effects of CSA and CSB Deficiency on Sensitivity to Oxidative DNA Damage H de Waard, J de Wit, JO Andressoo, CTM van Oostrom, B Riis, ... Molecular and Cellular Biology 24 (18), 7941-7948, 2004 | 119 | 2004 |
Nucleotide excision repair disorders and the balance between cancer and aging JO Andressoo, JHJ Hoeijmakers, JR Mitchell Cell cycle 5 (24), 2886-2888, 2006 | 106 | 2006 |
An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria JO Andressoo, JR Mitchell, J de Wit, D Hoogstraten, M Volker, ... Cancer cell 10 (2), 121-132, 2006 | 92 | 2006 |
Transcription-coupled repair and premature ageing JO Andressoo, JHJ Hoeijmakers Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 577 (1 …, 2005 | 92 | 2005 |
GDNF is not required for catecholaminergic neuron survival in vivo J Kopra, C Vilenius, S Grealish, MA Härma, K Varendi, J Lindholm, ... Nature neuroscience 18 (3), 319-322, 2015 | 73 | 2015 |
Signalling mechanisms underlying development and maintenance of dopamine neurons JO Andressoo, M Saarma Current opinion in neurobiology 18 (3), 297-306, 2008 | 73 | 2008 |
An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair JO Andressoo, G Weeda, J de Wit, JR Mitchell, RB Beems, H van Steeg, ... Molecular and cellular biology 29 (5), 1276-1290, 2009 | 67 | 2009 |
Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice M Van de Ven, JO Andressoo, VB Holcomb, M Von Lindern, WMC Jong, ... PLoS Genetics 2 (12), e192, 2006 | 67 | 2006 |
Implementation of deep neural networks to count dopamine neurons in substantia nigra AM Penttinen, I Parkkinen, S Blom, J Kopra, JO Andressoo, K Pitkänen, ... European Journal of Neuroscience 48 (6), 2354-2361, 2018 | 55 | 2018 |
Transcription-associated breaks in xeroderma pigmentosum group D cells from patients with combined features of xeroderma pigmentosum and Cockayne syndrome T Theron, MI Fousteri, M Volker, LW Harries, E Botta, M Stefanini, ... Molecular and cellular biology, 2005 | 54 | 2005 |
Dampened amphetamine-stimulated behavior and altered dopamine transporter function in the absence of brain GDNF JJ Kopra, A Panhelainen, S af Bjerkén, LL Porokuokka, K Varendi, S Olfat, ... Journal of Neuroscience 37 (6), 1581-1590, 2017 | 46 | 2017 |
Vascular endothelial growth factor C acts as a neurotrophic factor for dopamine neurons in vitro and in vivo M Piltonen, A Planken, O Leskelä, TT Myöhänen, AL Hänninen, ... Neuroscience 192, 550-563, 2011 | 45 | 2011 |