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Kevin Rychel
Kevin Rychel
在 eng.ucsd.edu 的电子邮件经过验证 - 首页
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iModulonDB: a knowledgebase of microbial transcriptional regulation derived from machine learning
K Rychel, K Decker, AV Sastry, PV Phaneuf, S Poudel, BO Palsson
Nucleic acids research 49 (D1), D112-D120, 2021
852021
Machine learning uncovers independently regulated modules in the Bacillus subtilis transcriptome
K Rychel, AV Sastry, BO Palsson
Nature communications 11 (1), 6338, 2020
622020
A multi-scale expression and regulation knowledge base for Escherichia coli
CR Lamoureux, KT Decker, AV Sastry, K Rychel, Y Gao, JL McConn, ...
Nucleic Acids Research 51 (19), 10176-10193, 2023
352023
Mining all publicly available expression data to compute dynamic microbial transcriptional regulatory networks
AV Sastry, S Poudel, K Rychel, R Yoo, CR Lamoureux, S Chauhan, ...
BioRxiv, 2021.07. 01.450581, 2021
342021
Machine-learning from Pseudomonas putida KT2440 transcriptomes reveals its transcriptional regulatory network
HG Lim, K Rychel, AV Sastry, GJ Bentley, J Mueller, HS Schindel, ...
Metabolic Engineering 72, 297-310, 2022
332022
Microporous polymer scaffolds for the transplantation of embryonic stem cell derived pancreatic progenitors to a clinically translatable site for the treatment of type I diabetes
T Kasputis, D Clough, F Noto, K Rychel, B Dye, LD Shea
ACS biomaterials science & engineering 4 (5), 1770-1778, 2018
332018
Machine learning of all Mycobacterium tuberculosis H37Rv RNA-seq data reveals a structured interplay between metabolism, stress response, and infection
R Yoo, K Rychel, S Poudel, T Al-Bulushi, Y Yuan, S Chauhan, ...
MSphere 7 (2), e00033-22, 2022
302022
Machine learning from Pseudomonas aeruginosa transcriptomes identifies independently modulated sets of genes associated with known transcriptional regulators
A Rajput, H Tsunemoto, AV Sastry, R Szubin, K Rychel, J Sugie, ...
Nucleic acids research 50 (7), 3658-3672, 2022
302022
Emerging themes and unifying concepts underlying cell behavior regulation by the pericellular space
KE Scott, K Rychel, S Ranamukhaarachchi, P Rangamani, SI Fraley
Acta biomaterialia 96, 81-98, 2019
242019
Machine Learning Uncovers a Data-Driven Transcriptional Regulatory Network for the Crenarchaeal Thermoacidophile Sulfolobus acidocaldarius
SM Chauhan, S Poudel, K Rychel, C Lamoureux, R Yoo, T Al Bulushi, ...
Frontiers in Microbiology 12, 753521, 2021
232021
Advanced transcriptomic analysis reveals the role of efflux pumps and media composition in antibiotic responses of Pseudomonas aeruginosa
A Rajput, H Tsunemoto, AV Sastry, R Szubin, K Rychel, SM Chauhan, ...
Nucleic acids research 50 (17), 9675-9688, 2022
192022
Laboratory evolution, transcriptomics, and modeling reveal mechanisms of paraquat tolerance
K Rychel, J Tan, A Patel, C Lamoureux, Y Hefner, R Szubin, J Johnsen, ...
Cell reports 42 (9), 2023
16*2023
Pan-genome analysis of transcriptional regulation in six Salmonella enterica serovar typhimurium strains reveals their different regulatory structures
Y Yuan, Y Seif, K Rychel, R Yoo, S Chauhan, S Poudel, T Al-Bulushi, ...
Msystems 7 (6), e00467-22, 2022
14*2022
Systems biology of competency in Vibrio natriegens is revealed by applying novel data analytics to the transcriptome
J Shin, K Rychel, BO Palsson
Cell Reports 42 (6), 2023
122023
Elucidation of independently modulated genes in Streptococcus pyogenes reveals carbon sources that control its expression of hemolytic toxins
Y Hirose, S Poudel, AV Sastry, K Rychel, CR Lamoureux, R Szubin, ...
Msystems 8 (3), e00247-23, 2023
82023
proChIPdb: a chromatin immunoprecipitation database for prokaryotic organisms
KT Decker, Y Gao, K Rychel, T Al Bulushi, SM Chauhan, D Kim, BK Cho, ...
Nucleic acids research 50 (D1), D1077-D1084, 2022
82022
Predicting stress response and improved protein overproduction in Bacillus subtilis
JD Tibocha-Bonilla, C Zuñiga, A Lekbua, C Lloyd, K Rychel, K Short, ...
NPJ Systems Biology and Applications 8 (1), 50, 2022
72022
Machine learning of all Mycobacterium tuberculosis H37Rv RNA-seq data reveals a structured interplay between metabolism, stress response, and infection. MSphere. 2022; 7 (2 …
R Yoo, K Rychel, S Poudel, T Al-Bulushi, Y Yuan, S Chauhan
DOI 10, 00033-22, 0
7
The hallmarks of a tradeoff in transcriptomes that balances stress and growth functions
C Dalldorf, K Rychel, R Szubin, Y Hefner, A Patel, DC Zielinski, ...
Msystems, e00305-24, 2024
62024
Proteome allocation is linked to transcriptional regulation through a modularized transcriptome
A Patel, D McGrosso, Y Hefner, A Campeau, AV Sastry, S Maurya, ...
Nature Communications 15 (1), 5234, 2024
52024
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