Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways B Psaila, N Barkas, D Iskander, A Roy, S Anderson, N Ashley, VS Caputo, ... Genome biology 17, 1-19, 2016 | 165 | 2016 |
Single-cell analyses reveal megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets B Psaila, G Wang, A Rodriguez-Meira, R Li, EF Heuston, L Murphy, D Yee, ... Molecular cell 78 (3), 477-492. e8, 2020 | 133 | 2020 |
Target enrichment and high‐throughput sequencing of 80 ribosomal protein genes to identify mutations associated with Diamond‐Blackfan anaemia G Gerrard, M Valgañón, HE Foong, D Kasperaviciute, D Iskander, L Game, ... British journal of haematology 162 (4), 530-536, 2013 | 61 | 2013 |
Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development A Roy, G Wang, D Iskander, S O’Byrne, N Elliott, J O’Sullivan, G Buck, ... Cell Reports 36 (11), 2021 | 48 | 2021 |
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia D Iskander, G Wang, EF Heuston, C Christodoulidou, B Psaila, ... Science translational medicine 13 (610), eabf0113, 2021 | 46 | 2021 |
Elucidation of the EP defect in Diamond-Blackfan anemia by characterization and prospective isolation of human EPs D Iskander, B Psaila, G Gerrard, A Chaidos, H En Foong, Y Harrington, ... Blood, The Journal of the American Society of Hematology 125 (16), 2553-2557, 2015 | 43 | 2015 |
Transcriptional and epigenetic basis for restoration of G6PD enzymatic activity in human G6PD-deficient cells K Makarona, VS Caputo, JR Costa, B Liu, D O’Connor, D Iskander, ... Blood, The Journal of the American Society of Hematology 124 (1), 134-141, 2014 | 30 | 2014 |
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia E Louka, B Povinelli, A Rodriguez-Meira, G Buck, WX Wen, G Wang, ... Journal of Experimental Medicine 218 (2), 2021 | 28 | 2021 |
Impaired cellular and humoral immunity is a feature of Diamond‐Blackfan anaemia; experience of 107 unselected cases in the United Kingdom D Iskander, I Roberts, C Rees, R Szydlo, M Alikian, M Neale, Y Harrington, ... British Journal of Haematology 186 (2), 321-326, 2019 | 26 | 2019 |
The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma K Ponnusamy, MM Tzioni, M Begum, ME Robinson, VS Caputo, ... Haematologica 107 (3), 721, 2022 | 24 | 2022 |
Diamond-Blackfan anemia in adults: In pursuit of a common approach for a rare disease D Iskander, NBA Roy, E Payne, E Drasar, K Hennessy, Y Harrington, ... Blood reviews 61, 101097, 2023 | 7 | 2023 |
Diagnosis, treatment, and surveillance of Diamond-Blackfan anaemia syndrome: international consensus statement MW Wlodarski, A Vlachos, JE Farrar, LM Da Costa, A Kattamis, I Dianzani, ... The Lancet Haematology 11 (5), e368-e382, 2024 | 5 | 2024 |
Thrombotic microangiopathy complicating pegylated interferon treatment of hepatitis C infection D Iskander, M Wickremasinghe, BJ Bain American journal of hematology 86 (10), 859-859, 2011 | 4 | 2011 |
Two’s company but three’sa blast! D Iskander Blood, The Journal of the American Society of Hematology 140 (14), 1578-1580, 2022 | 3 | 2022 |
Patients with Diamond Blackfan anaemia have abnormalities of cellular and humoral immunity D Iskander, Y Harrington, I Roberts, A Karadimitris, J de la Fuente Blood 120 (21), 3484, 2012 | 3 | 2012 |
Harnessing Single-Cell Technologies in the Search for New Therapies for Diamond–Blackfan Anemia Syndrome D Iskander, A Karadimitris, I Roberts Experimental Hematology 135, 2024 | 1 | 2024 |
The molecular basis of bone marrow failure syndromes and red cell enzymopathies D Iskander, L Luzzatto, A Karadimitris Molecular Hematology, 145-168, 2024 | 1 | 2024 |
Single-Cell Transcriptional Landscapes of Human Bone Marrow Reveal Distinct Erythroid Phenotypes Underpinned By Genotype in Diamond-Blackfan Anemia D Iskander, G Wang, EF Heuston, C Christodoulidou, B Psaila, ... Blood 136, 1-2, 2020 | 1 | 2020 |
Clinical and genetic diversity in Diamond-Blackfan anaemia: an update from the United Kingdom D Iskander, C Miller, M Alikian, Y Harrington, Q Al-Oqaily, I Roberts, ... haematologica 102 (S2), 2017 | 1 | 2017 |
Developmental stage specific B-progenitor expansion in normal fetal bone marrow is absent in down syndrome: implications for infant ALL A Roy, G Bohn, K Goudevenou, G Cowan, N Bhatnagar, D O’Connor, ... Blood 124 (21), 4331, 2014 | 1 | 2014 |