| Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity DW Lamming, L Ye, P Katajisto, MD Goncalves, M Saitoh, DM Stevens, ... science 335 (6076), 1638-1643, 2012 | 1340 | 2012 |
| Suppression of insulin feedback enhances the efficacy of PI3K inhibitors BD Hopkins, C Pauli, X Du, DG Wang, X Li, D Wu, SC Amadiume, ... Nature 560 (7719), 499-503, 2018 | 590 | 2018 |
| Obesity and cancer mechanisms: cancer metabolism BD Hopkins, MD Goncalves, LC Cantley Journal of clinical oncology 34 (35), 4277-4283, 2016 | 345 | 2016 |
| High-fructose corn syrup enhances intestinal tumor growth in mice MD Goncalves, C Lu, J Tutnauer, TE Hartman, SK Hwang, CJ Murphy, ... Science 363 (6433), 1345-1349, 2019 | 314 | 2019 |
| Phosphatidylinositol 3-kinase, growth disorders, and cancer MD Goncalves, BD Hopkins, LC Cantley New England Journal of Medicine 379 (21), 2052-2062, 2018 | 282 | 2018 |
| An atlas of substrate specificities for the human serine/threonine kinome JL Johnson, TM Yaron, EM Huntsman, A Kerelsky, J Song, A Regev, ... Nature 613 (7945), 759-766, 2023 | 263 | 2023 |
| Insulin–PI3K signalling: an evolutionarily insulated metabolic driver of cancer BD Hopkins, MD Goncalves, LC Cantley Nature Reviews Endocrinology 16 (5), 276-283, 2020 | 234 | 2020 |
| The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity I Akpan, MD Goncalves, R Dhir, X Yin, EE Pistilli, S Bogdanovich, ... International journal of obesity 33 (11), 1265-1273, 2009 | 214 | 2009 |
| Dietary fructose improves intestinal cell survival and nutrient absorption SR Taylor, S Ramsamooj, RJ Liang, A Katti, R Pozovskiy, N Vasan, ... Nature 597 (7875), 263-267, 2021 | 185 | 2021 |
| Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy EE Pistilli, S Bogdanovich, MD Goncalves, RS Ahima, J Lachey, J Seehra, ... The American journal of pathology 178 (3), 1287-1297, 2011 | 120 | 2011 |
| Fenofibrate prevents skeletal muscle loss in mice with lung cancer MD Goncalves, SK Hwang, C Pauli, CJ Murphy, Z Cheng, BD Hopkins, ... Proceedings of the National Academy of Sciences 115 (4), E743-E752, 2018 | 113 | 2018 |
| Developing dietary interventions as therapy for cancer SR Taylor, JN Falcone, LC Cantley, MD Goncalves Nature Reviews Cancer 22 (8), 452-466, 2022 | 85 | 2022 |
| Phosphatidylinositol-5-phosphate 4-kinases regulate cellular lipid metabolism by facilitating autophagy MR Lundquist, MD Goncalves, RM Loughran, E Possik, T Vijayaraghavan, ... Molecular cell 70 (3), 531-544. e9, 2018 | 84 | 2018 |
| Oscillatory phosphorylation of yeast Fus3 MAP kinase controls periodic gene expression and morphogenesis Z Hilioti, W Sabbagh, S Paliwal, A Bergmann, MD Goncalves, L Bardwell, ... Current biology 18 (21), 1700-1706, 2008 | 77 | 2008 |
| Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition MD Goncalves, EE Pistilli, A Balduzzi, MJ Birnbaum, J Lachey, ... PloS one 5 (9), e12707, 2010 | 67 | 2010 |
| Rac-mediated macropinocytosis of extracellular protein promotes glucose independence in non-small cell lung cancer C Hodakoski, BD Hopkins, G Zhang, T Su, Z Cheng, R Morris, KY Rhee, ... Cancers 11 (1), 37, 2019 | 55 | 2019 |
| Cachexia: A systemic consequence of progressive, unresolved disease M Ferrer, TG Anthony, JS Ayres, G Biffi, JC Brown, BJ Caan, ... Cell 186 (9), 1824-1845, 2023 | 51 | 2023 |
| Optimal management of adverse events from copanlisib in the treatment of patients with non-Hodgkin lymphomas BD Cheson, S O’Brien, MS Ewer, MD Goncalves, A Farooki, G Lenz, A Yu, ... Clinical Lymphoma Myeloma and Leukemia 19 (3), 135-141, 2019 | 50 | 2019 |
| Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer AL Queiroz, E Dantas, S Ramsamooj, A Murthy, M Ahmed, ERM Zunica, ... Nature Communications 13 (1), 4633, 2022 | 43 | 2022 |
| Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia M Ferrer, N Mourikis, EE Davidson, SO Kleeman, M Zaccaria, J Habel, ... Cell metabolism 35 (7), 1147-1162. e7, 2023 | 40 | 2023 |
Lewis CantleyDana Farber Cancer Center and Harvard Medical School在 med.cornell.edu 的电子邮件经过验证
