Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite. LD Buttery, DR Springall, AH Chester, TJ Evans, EN Standfield, ... Laboratory investigation; a journal of technical methods and pathology 75 (1 …, 1996 | 543 | 1996 |
Vascular smooth muscle cell calcification is mediated by regulated exosome secretion AN Kapustin, MLL Chatrou, I Drozdov, Y Zheng, SM Davidson, D Soong, ... Circulation research 116 (8), 1312-1323, 2015 | 510 | 2015 |
Mitral valve disease—morphology and mechanisms RA Levine, AA Hagége, DP Judge, M Padala, JP Dal-Bianco, E Aikawa, ... Nature reviews cardiology 12 (12), 689-710, 2015 | 397 | 2015 |
Nano-analytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification S Bertazzo, E Gentleman, KL Cloyd, AH Chester, MH Yacoub, ... Nature materials 12 (6), 576-583, 2013 | 313 | 2013 |
Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries AH Chester, GS O'neil, S Tadjkarimi, MH Yacoub, S Moncada The Lancet 336 (8720), 897-900, 1990 | 302 | 1990 |
Role of human valve interstitial cells in valve calcification and their response to atorvastatin L Osman, MH Yacoub, N Latif, M Amrani, AH Chester Circulation 114 (1_supplement), I-547-I-552, 2006 | 290 | 2006 |
Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch CH Ku, PH Johnson, P Batten, P Sarathchandra, RC Chambers, ... Cardiovascular research 71 (3), 548-556, 2006 | 263 | 2006 |
Differential distribution of angiotensin AT2receptors in the normal and failing human heart J Wharton, K Morgan, RAD Rutherford, JD Catravas, A Chester, ... Journal of Pharmacology and Experimental Therapeutics 284 (1), 323-336, 1998 | 216 | 1998 |
Mutations in DCHS1 cause mitral valve prolapse R Durst, K Sauls, DS Peal, A Devlaming, K Toomer, M Leyne, M Salani, ... Nature 525 (7567), 109-113, 2015 | 205 | 2015 |
The role of endothelin-1 in pulmonary arterial hypertension AH Chester, MH Yacoub Global Cardiology Science and Practice 2014 (2), 29, 2014 | 192 | 2014 |
Side-specific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling J Richards, I El-Hamamsy, S Chen, Z Sarang, P Sarathchandra, ... The American journal of pathology 182 (5), 1922-1931, 2013 | 190 | 2013 |
Molecular and functional characteristics of heart-valve interstitial cells AH Chester, PM Taylor Philosophical Transactions of the Royal Society B: Biological Sciences 362 …, 2007 | 184 | 2007 |
Endothelium-dependent regulation of the mechanical properties of aortic valve cusps I El-Hamamsy, K Balachandran, MH Yacoub, LM Stevens, ... Journal of the American College of Cardiology 53 (16), 1448-1455, 2009 | 181 | 2009 |
Oestrogen relaxes human epicardial coronary arteries through non-endothelium-dependent mechanisms AH Chester, C Jiang, JA Borland, MH Yacoub, P Collins Coronary artery disease 6 (5), 417-422, 1995 | 170 | 1995 |
Functional crosstalk between cardiac fibroblasts and adult cardiomyocytes by soluble mediators JE Cartledge, C Kane, P Dias, M Tesfom, L Clarke, B Mckee, S Al Ayoubi, ... Cardiovascular research 105 (3), 260-270, 2015 | 157 | 2015 |
Role of potassium concentration in cardioplegic solutions in mediating endothelial damage PS Mankad, AH Chester, MH Yacoub The Annals of thoracic surgery 51 (1), 89-93, 1991 | 143 | 1991 |
Clinical and haemodynamic effects of sildenafil in pulmonary hypertension: acute and mid-term effects GW Mikhail, SK Prasad, W Li, P Rogers, AH Chester, S Bayne, ... European Heart Journal 25 (5), 431-436, 2004 | 142 | 2004 |
5-Hydroxytryptamine receptor profile in healthy and diseased human epicardial coronary arteries AH Chester, GR Martin, M Bodelsson, B Arneklo-Nobin, S Tadjkarimi, ... Cardiovascular research 24 (11), 932-937, 1990 | 137 | 1990 |
Extracellular matrix production by adipose-derived stem cells: implications for heart valve tissue engineering F Colazzo, P Sarathchandra, RT Smolenski, AH Chester, YT Tseng, ... Biomaterials 32 (1), 119-127, 2011 | 134 | 2011 |
Atrioventricular valve development: new perspectives on an old theme A de Vlaming, K Sauls, Z Hajdu, RP Visconti, AN Mehesz, RA Levine, ... Differentiation 84 (1), 103-116, 2012 | 132 | 2012 |