Mice devoid of PrP are resistant to scrapie H Büeler, A Aguzzi, A Sailer, RA Greiner, P Autenried, M Aguet, ... Cell 73 (7), 1339-1347, 1993 | 2667 | 1993 |
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud F Bladt, D Riethmacher, S Isenmann, A Aguzzi, C Birchmeier Nature 376 (6543), 768-771, 1995 | 1618 | 1995 |
An analytical solution to the kinetics of breakable filament assembly TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ... Science 326 (5959), 1533-1537, 2009 | 1207 | 2009 |
Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. TJ Cole, JA Blendy, AP Monaghan, K Krieglstein, W Schmid, A Aguzzi, ... Genes & development 9 (13), 1608-1621, 1995 | 1116 | 1995 |
Prion protein (PrP) with amino‐proximal deletions restoring susceptibility of PrP knockout mice to scrapie. M Fischer, T Rülicke, A Raeber, A Sailer, M Moser, B Oesch, S Brandner, ... The EMBO journal 15 (6), 1255-1264, 1996 | 1080 | 1996 |
Microglia: scapegoat, saboteur, or something else? A Aguzzi, BA Barres, ML Bennett Science 339 (6116), 156-161, 2013 | 1008 | 2013 |
Normal host prion protein necessary for scrapie-induced neurotoxicity S Brandner, A Raeber, M Fischer, A Sailer, Y Kobayashi, ... Nature 379, 25, 1996 | 991 | 1996 |
Experimental autoimmune encephalomyelitis repressed by microglial paralysis FL Heppner, M Greter, D Marino, J Falsig, G Raivich, N Hövelmeyer, ... Nature medicine 11 (2), 146-152, 2005 | 910 | 2005 |
Protein aggregation diseases: pathogenicity and therapeutic perspectives A Aguzzi, T O'connor Nature reviews Drug discovery 9 (3), 237-248, 2010 | 893 | 2010 |
Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase. YL Yang, LF Reis, J Pavlovic, A Aguzzi, R Schäfer, A Kumar, BR Williams, ... The EMBO journal 14 (24), 6095-6106, 1995 | 818 | 1995 |
The adaptor ASC has extracellular and'prionoid'activities that propagate inflammation BS Franklin, L Bossaller, D De Nardo, JM Ratter, A Stutz, G Engels, ... Nature immunology 15 (8), 727-737, 2014 | 812 | 2014 |
Mammalian prion biology: one century of evolving concepts A Aguzzi, M Polymenidou Cell 116 (2), 313-327, 2004 | 760 | 2004 |
p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases K Zatloukal, C Stumptner, A Fuchsbichler, H Heid, M Schnoelzer, ... The American journal of pathology 160 (1), 255-263, 2002 | 717 | 2002 |
The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice S Calogero, F Grassi, A Aguzzi, T Voigtländer, P Ferrier, S Ferrari, ... Nature genetics 22 (3), 276-280, 1999 | 667 | 1999 |
Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. B Adams, P Dörfler, A Aguzzi, Z Kozmik, P Urbanek, I Maurer-Fogy, ... Genes & development 6 (9), 1589-1607, 1992 | 664 | 1992 |
Prions: protein aggregation and infectious diseases A Aguzzi, AM Calella Physiological reviews 89 (4), 1105-1152, 2009 | 655 | 2009 |
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members S Heber, J Herms, V Gajic, J Hainfellner, A Aguzzi, T Rülicke, ... Journal of Neuroscience 20 (21), 7951-7963, 2000 | 649 | 2000 |
A crucial role for B cells in neuroinvasive scrapie MA Klein, R Frigg, E Flechsig, AJ Raeber, U Kalinke, H Bluethmann, ... Nature 390 (6661), 687-690, 1997 | 647 | 1997 |
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions D Shmerling, I Hegyi, M Fischer, T Blättler, S Brandner, J Götz, T Rülicke, ... Cell 93 (2), 203-214, 1998 | 642 | 1998 |
Microglia states and nomenclature: A field at its crossroads RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ... Neuron 110 (21), 3458-3483, 2022 | 629 | 2022 |