Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5 B Wu, A Peisley, C Richards, H Yao, X Zeng, C Lin, F Chu, T Walz, S Hur Cell 152 (1), 276-289, 2013 | 597 | 2013 |
Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I A Peisley, B Wu, H Xu, ZJ Chen, S Hur Nature 509 (7498), 110-114, 2014 | 342 | 2014 |
Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition A Peisley, C Lin, B Wu, MG Orme-Johnson, M Liu, T Walz, S Hur Proceedings of the National Academy of Sciences 108 (52), 21010-21015, 2011 | 322 | 2011 |
RIG-I forms signaling-competent filaments in an ATP-dependent, ubiquitin-independent manner A Peisley, B Wu, H Yao, T Walz, S Hur Molecular cell 51 (5), 573-583, 2013 | 245 | 2013 |
Molecular imprinting as a signal-activation mechanism of the viral RNA sensor RIG-I B Wu, A Peisley, D Tetrault, Z Li, EH Egelman, KE Magor, T Walz, ... Molecular cell 55 (4), 511-523, 2014 | 242 | 2014 |
How RIG-I like receptors activate MAVS B Wu, S Hur Current opinion in virology 12, 91-98, 2015 | 224 | 2015 |
The mechanics behind DNA sequence-dependent properties of the nucleosome EYD Chua, D Vasudevan, GE Davey, B Wu, CA Davey Nucleic acids research 40 (13), 6338-6352, 2012 | 198 | 2012 |
Engineering a catalytically efficient recombinant protein ligase R Yang, YH Wong, GKT Nguyen, JP Tam, J Lescar, B Wu Journal of the American Chemical Society 139 (15), 5351-5358, 2017 | 195 | 2017 |
A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core B Wu, MS Ong, M Groessl, Z Adhireksan, CG Hartinger, PJ Dyson, ... Chemistry–A European Journal 13 (17), 3562-3566, 2011 | 192 | 2011 |
Kinetic mechanism for viral dsRNA length discrimination by MDA5 filaments A Peisley, MH Jo, C Lin, B Wu, MG Orme-Johnson, T Walz, S Hohng, ... Proceedings of the National Academy of Sciences 109 (49), E3340-E3349, 2012 | 164 | 2012 |
TIR domains of plant immune receptors are 2′, 3′-cAMP/cGMP synthetases mediating cell death D Yu, W Song, EYJ Tan, L Liu, Y Cao, J Jirschitzka, E Li, E Logemann, ... Cell 185 (13), 2370-2386. e18, 2022 | 124 | 2022 |
Structural and biochemical mechanisms of NLRP1 inhibition by DPP9 M Huang, X Zhang, GA Toh, Q Gong, J Wang, Z Han, B Wu, F Zhong, ... Nature 592 (7856), 773-777, 2021 | 114 | 2021 |
Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa J Fong, C Zhang, R Yang, ZZ Boo, SK Tan, TE Nielsen, M Givskov, ... Scientific reports 8 (1), 1155, 2018 | 98 | 2018 |
Enzymatic biosynthesis and immobilization of polyprotein verified at the single-molecule level Y Deng, T Wu, M Wang, S Shi, G Yuan, X Li, H Chong, B Wu, P Zheng Nature communications 10 (1), 2775, 2019 | 92 | 2019 |
Site selectivity of platinum anticancer therapeutics B Wu, P Dröge, CA Davey Nature chemical biology 4 (2), 110-112, 2008 | 92 | 2008 |
MDA5—filament, dynamics and disease Y del Toro Duany, B Wu, S Hur Current opinion in virology 12, 20-25, 2015 | 75 | 2015 |
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome KS Robinson, GA Toh, P Rozario, R Chua, S Bauernfried, Z Sun, ... Science 377 (6603), 328-335, 2022 | 73 | 2022 |
Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8 Q Gong, K Robinson, C Xu, PT Huynh, KHC Chong, EYJ Tan, J Zhang, ... Nature communications 12 (1), 188, 2021 | 68 | 2021 |
Structural basis of RIP2 activation and signaling Q Gong, Z Long, FL Zhong, DET Teo, Y Jin, Z Yin, ZZ Boo, Y Zhang, ... Nature communications 9 (1), 4993, 2018 | 67 | 2018 |
Structural insight into the sequence dependence of nucleosome positioning B Wu, K Mohideen, D Vasudevan, CA Davey Structure 18 (4), 528-536, 2010 | 47 | 2010 |