Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis Nature 476 (7359), 214-219, 2011 | 2996 | 2011 |
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis International IBD Genetics Consortium (IIBDGC), C Agliardi, L Alfredsson, ... Nature genetics 45 (11), 1353-1360, 2013 | 1346 | 2013 |
Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity R Roxburgh, SR Seaman, T Masterman, AE Hensiek, SJ Sawcer, ... Neurology 64 (7), 1144-1151, 2005 | 1071 | 2005 |
ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis X Montalban, R Gold, AJ Thompson, S Otero-Romero, MP Amato, ... Multiple Sclerosis Journal 24 (2), 96-120, 2018 | 929 | 2018 |
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019 | 922 | 2019 |
Genetic cell ablation reveals clusters of local self-renewing microglia in the mammalian central nervous system J Bruttger, K Karram, S Wörtge, T Regen, F Marini, N Hoppmann, M Klein, ... Immunity 43 (1), 92-106, 2015 | 661 | 2015 |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database CM Lill, JT Roehr, MB McQueen, FK Kavvoura, S Bagade, BMM Schjeide, ... PLoS genetics 8 (3), e1002548, 2012 | 613 | 2012 |
Sirt1 contributes critically to the redox-dependent fate of neural progenitors T Prozorovski, U Schulze-Topphoff, R Glumm, J Baumgart, F Schröter, ... Nature cell biology 10 (4), 385-394, 2008 | 529 | 2008 |
The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases F Zipp, O Aktas Trends in neurosciences 29 (9), 518-527, 2006 | 447 | 2006 |
Green tea epigallocatechin-3-gallate mediates T cellular NF-κB inhibition and exerts neuroprotection in autoimmune encephalomyelitis O Aktas, T Prozorovski, A Smorodchenko, NE Savaskan, R Lauster, ... The Journal of Immunology 173 (9), 5794-5800, 2004 | 408 | 2004 |
Class II HLA interactions modulate genetic risk for multiple sclerosis Nature genetics 47 (10), 1107-1113, 2015 | 401 | 2015 |
Mechanisms of disease: aquaporin-4 antibodies in neuromyelitis optica S Jarius, F Paul, D Franciotta, P Waters, F Zipp, R Hohlfeld, A Vincent, ... Nature clinical practice Neurology 4 (4), 202-214, 2008 | 401 | 2008 |
Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL) R Nitsch, I Bechmann, RA Deisz, D Haas, TN Lehmann, U Wendling, ... The Lancet 356 (9232), 827-828, 2000 | 385 | 2000 |
Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin O Aktas, S Waiczies, A Smorodchenko, J Dörr, B Seeger, T Prozorovski, ... The Journal of experimental medicine 197 (6), 725-733, 2003 | 372 | 2003 |
Immunoneuropsychiatry—novel perspectives on brain disorders K Pape, R Tamouza, M Leboyer, F Zipp Nature Reviews Neurology 15 (6), 317-328, 2019 | 363 | 2019 |
MR-elastography reveals degradation of tissue integrity in multiple sclerosis J Wuerfel, F Paul, B Beierbach, U Hamhaber, D Klatt, S Papazoglou, ... Neuroimage 49 (3), 2520-2525, 2010 | 363 | 2010 |
In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis V Siffrin, H Radbruch, R Glumm, R Niesner, M Paterka, J Herz, ... Immunity 33 (3), 424-436, 2010 | 351 | 2010 |
Indolamine 2, 3‐dioxygenase is expressed in the CNS and down‐regulates autoimmune inflammation E Kwidzinski, J Bunse, O Aktas, D Richter, L Mutlu, F Zipp, R Nitsch, ... The FASEB Journal 19 (10), 1347-1349, 2005 | 340 | 2005 |
Neuronal damage in brain inflammation O Aktas, O Ullrich, C Infante-Duarte, R Nitsch, F Zipp Archives of neurology 64 (2), 185-189, 2007 | 295 | 2007 |
Microglia–blood vessel interactions: a double-edged sword in brain pathologies N Dudvarski Stankovic, M Teodorczyk, R Ploen, F Zipp, MHH Schmidt Acta neuropathologica 131 (3), 347-363, 2016 | 285 | 2016 |