Novel 5-(2-hydroxyphenyl)-3-substituted-2, 3-dihydro-1, 3, 4-oxadiazole-2-thione derivatives: Promising anticancer agents AS Aboraia, HM Abdel-Rahman, NM Mahfouz, MA El-Gendy Bioorganic & medicinal chemistry 14 (4), 1236-1246, 2006 | 314 | 2006 |
Synthesis, theoretical investigations, biocidal screening, DNA binding, in vitro cytotoxicity and molecular docking of novel Cu (II), Pd (II) and Ag (I) complexes of … LH Abdel‐Rahman, MSS Adam, AM Abu‐Dief, H Moustafa, MT Basha, ... Applied Organometallic Chemistry 32 (12), e4527, 2018 | 161 | 2018 |
Design, synthesis, docking studies and biological evaluation of novel chalcone derivatives as potential histone deacetylase inhibitors MFA Mohamed, MSA Shaykoon, MH Abdelrahman, BEM Elsadek, ... Bioorganic chemistry 72, 32-41, 2017 | 64 | 2017 |
Design, synthesis, and antibacterial evaluation of new quinoline-1, 3, 4-oxadiazole and quinoline-1, 2, 4-triazole hybrids as potential inhibitors of DNA gyrase and … HA Hofny, MFA Mohamed, HAM Gomaa, SA Abdel-Aziz, BGM Youssif, ... Bioorganic Chemistry 112, 104920, 2021 | 45 | 2021 |
Utilization of tetrahydrobenzo [4, 5] thieno [2, 3-d] pyrimidinone as a cap moiety in design of novel histone deacetylase inhibitors MFA Mohamed, BGM Youssif, MSA Shaykoon, MH Abdelrahman, ... Bioorganic chemistry 91, 103127, 2019 | 44 | 2019 |
Design, synthesis and pharmacophoric model building of new 3‐alkoxymethyl/3‐phenyl indole‐2‐carboxamides with potential antiproliferative activity MH Abdelrahman, AS Aboraia, BGM Youssif, BEM Elsadek Chemical biology & drug design 90 (1), 64-82, 2017 | 40 | 2017 |
Synthesis and CYP24A1 inhibitory activity of (E)-2-(2-substituted benzylidene)-and 2-(2-substituted benzyl)-6-methoxy-tetralones AS Aboraia, B Makowski, A Bahja, D Prosser, A Brancale, G Jones, ... European journal of medicinal chemistry 45 (10), 4427-4434, 2010 | 40 | 2010 |
Rahman-abdel. M hamdy, Mahouz M. nadia,“Novel 5-(2 hydroxyphenyl)-3-substituted-2, 3-dihydro-1, 3, 4-oxadiazole-2-thione derivatives: Promising anticancer agents.” AS Ahmed Bioorganic & Medicinal Chemistry 14, 1236-1246, 2006 | 38 | 2006 |
Annonaceous Acetogenins as a new anticancer agent WS Qayed, AS Aboraia, HM Abdel-Rahman, AF Youssef | 35 | 2015 |
Small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26): synthesis and biological evaluation of imidazole methyl 3-(4-(aryl-2-ylamino) phenyl) propanoates MS Gomaa, CE Bridgens, AS Aboraia, GJ Veal, CPF Redfern, A Brancale, ... Journal of medicinal chemistry 54 (8), 2778-2791, 2011 | 32 | 2011 |
Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2-phenylethyl) arylamides AS Aboraia, SW Yee, MS Gomaa, N Shah, AC Robotham, B Makowski, ... Bioorganic & medicinal chemistry 18 (14), 4939-4946, 2010 | 24 | 2010 |
Small-molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): synthesis and biological evaluation S Ferla, AS Aboraia, A Brancale, CJ Pepper, J Zhu, JT Ochalek, ... Journal of Medicinal Chemistry 57 (18), 7702-7715, 2014 | 20 | 2014 |
Bioactive fluorenes. Part III: 2,7-dichloro-9H-fluorene-based thiazolidinone and azetidinone analogues as anticancer and antimicrobial against multidrug resistant … EM Hussein, RI Alsantali, M Morad, RJ Obaid, HM Altass, A Sayqal, ... BMC chemistry 14, 1-24, 2020 | 16 | 2020 |
Design, synthesis and evaluation against Mycobacterium tuberculosis of azole piperazine derivatives as dicyclotyrosine (cYY) mimics HAA Abd El-wahab, M Accietto, LB Marino, KJ McLean, CW Levy, ... Bioorganic & Medicinal Chemistry 26 (1), 161-176, 2018 | 14 | 2018 |
Lipases-catalyzed enantioselective kinetic resolution of alcohols WS Qayed, AS Aboraia, HM Abdel-Rahman, AF Youssef Journal of Chemical and Pharmaceutical Research 7 (5), 311-322, 2015 | 13 | 2015 |
Synthesis, computational study and biological evaluation of 9-acridinyl and 1-coumarinyl-1, 2, 3-triazole-4-yl derivatives as topoisomerase II inhibitors GA Abdel-Hafez, AMI Mohamed, AF Youssef, C Simons, AS Aboraia Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 502-513, 2022 | 10 | 2022 |
Salting‐out thin‐layer chromatography and computational analysis of some oral hypoglycemic drugs AMI Mohamed, FAF Mohamed, SAR Ahmed, AS Aboraia, YAS Mohamed Biomedical Chromatography 28 (8), 1156-1162, 2014 | 10 | 2014 |
In depth investigation of the retention behavior of structurally related β-blockers on RP-HPLC column: Quality by design and quantitative structure-property relationship … AFA Hakiem, AK Hamdy, HRH Ali, M Gomaa, AS Aboraia Journal of Chromatography B 1166, 122549, 2021 | 9 | 2021 |
Design and synthesis of substituted imidazole and triazole N-phenylbenzo[d]oxazolamine inhibitors of retinoic acid metabolizing enzyme CYP26 S Pautus, AS Aboraia, CE Bassett, A Brancale, MP Coogan, C Simons Journal of Enzyme Inhibition and Medicinal Chemistry 24 (2), 487-498, 2009 | 9 | 2009 |
N4-substituted piperazinyl norfloxacin derivatives with broad-spectrum activity and multiple mechanisms on gyrase, topoisomerase IV, and bacterial cell wall synthesis AM Kamal El-sagheir, I Abdelmesseh Nekhala, MK Abd El-Gaber, ... ACS bio & med chem Au 3 (6), 494-506, 2023 | 4 | 2023 |