Mitochondrial DNA–deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers E Bua, J Johnson, A Herbst, B Delong, D McKenzie, S Salamat, JM Aiken The American Journal of Human Genetics 79 (3), 469-480, 2006 | 498 | 2006 |
Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia J Wanagat, Z Cao, P Pathare, JM Aiken The FASEB Journal 15 (2), 322-332, 2001 | 456 | 2001 |
Prions adhere to soil minerals and remain infectious CJ Johnson, KE Phillips, PT Schramm, D McKenzie, JM Aiken, ... PLoS pathogens 2 (4), e32, 2006 | 371 | 2006 |
Oral transmissibility of prion disease is enhanced by binding to soil particles CJ Johnson, JA Pedersen, RJ Chappell, D McKenzie, JM Aiken PLoS Pathogens 3 (7), e93, 2007 | 287 | 2007 |
Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia EA Bua, SH McKiernan, J Wanagat, D McKenzie, JM Aiken Journal of applied physiology 92 (6), 2617-2624, 2002 | 275 | 2002 |
Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber loss A Herbst, JW Pak, D McKenzie, E Bua, M Bassiouni, JM Aiken The Journals of Gerontology Series A: Biological Sciences and Medical …, 2007 | 220 | 2007 |
Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection Z Cao, J Wanagat, SH McKiernan, JM Aiken Nucleic acids research 29 (21), 4502-4508, 2001 | 216 | 2001 |
Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle LE Aspnes, CM Lee, R Weindruch, SS Chung, EB Roecker, JM Aiken The FASEB Journal 11 (7), 573-581, 1997 | 199 | 1997 |
Prion protein polymorphisms in white-tailed deer influence susceptibility to chronic wasting disease C Johnson, J Johnson, JP Vanderloo, D Keane, JM Aiken, D McKenzie Journal of General Virology 87 (7), 2109-2114, 2006 | 191 | 2006 |
Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy JC Bartz, RA Bessen, D McKenzie, RF Marsh, JM Aiken Journal of virology 74 (12), 5542-5547, 2000 | 186 | 2000 |
The host range of chronic wasting disease is altered on passage in ferrets JC Bartz, RF Marsh, DI McKenzie, JM Aiken Virology 251 (2), 297-301, 1998 | 178 | 1998 |
Reversibility of scrapie inactivation is enhanced by copper D McKenzie, J Bartz, J Mirwald, D Olander, R Marsh, J Aiken Journal of Biological Chemistry 273 (40), 25545-25547, 1998 | 164 | 1998 |
Age-associated alterations of the mitochondrial genome CM Lee, R Weindruch, JM Aiken Free Radical biology and medicine 22 (7), 1259-1269, 1997 | 162 | 1997 |
Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy CM Lee, ME Lopez, R Weindruch, JM Aiken Free Radical Biology and Medicine 25 (8), 964-972, 1998 | 152 | 1998 |
High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys SR Schwarze, CM Lee, SS Chung, EB Roecker, R Weindruch, JM Aiken Mechanisms of ageing and development 83 (2), 91-101, 1995 | 146 | 1995 |
Persistence and expression of Microplitis demolitor polydnavirus in Pseudoplusia includens MR Strand, DI McKenzie, V Grassl, BA Dover, JM Aiken Journal of General Virology 73 (7), 1627-1635, 1992 | 146 | 1992 |
Multiple mitochondrial DNA deletions associated with age in skeletal muscle of rhesus monkeys CM Lee, SS Chung, JM Kaczkowski, R Weindruch, JM Aiken Journal of Gerontology 48 (6), B201-B205, 1993 | 137 | 1993 |
Mitochondrial DNA deletion mutations: a causal role in sarcopenia D McKenzie, E Bua, S McKiernan, Z Cao, Jonathan Wanagat, JM Aiken European Journal of Biochemistry 269 (8), 2010-2015, 2002 | 129 | 2002 |
Oxidative stress and aging reduce COX I RNA and cytochrome oxidase activity in Drosophila SR Schwarze, R Weindruch, JM Aiken Free Radical Biology and Medicine 25 (6), 740-747, 1998 | 122 | 1998 |
Age-related changes in cardiac structure and function in Fischer 344× Brown Norway hybrid rats TA Hacker, SH McKiernan, PS Douglas, J Wanagat, JM Aiken American Journal of Physiology-Heart and Circulatory Physiology 290 (1 …, 2006 | 121 | 2006 |