Patient-specific induced pluripotent stem-cell models for long-QT syndrome A Moretti, M Bellin, A Welling, CB Jung, JT Lam, L Bott-Flügel, T Dorn, ... New England Journal of Medicine 363 (15), 1397-1409, 2010 | 1447 | 2010 |
Dantrolene rescues arrhythmogenic RYR2 defect in a patient‐specific stem cell model of catecholaminergic polymorphic ventricular tachycardia CB Jung, A Moretti, M Mederos y Schnitzler, L Iop, U Storch, M Bellin, ... EMBO molecular medicine 4 (3), 180-191, 2012 | 372 | 2012 |
Reversible photobleaching of enhanced green fluorescent proteins D Sinnecker, P Voigt, N Hellwig, M Schaefer Biochemistry 44 (18), 7085-7094, 2005 | 253 | 2005 |
Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy A Moretti, L Fonteyne, F Giesert, P Hoppmann, AB Meier, T Bozoglu, ... Nature medicine 26 (2), 207-214, 2020 | 214 | 2020 |
Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes M Rocchetti, L Sala, L Dreizehnter, L Crotti, D Sinnecker, M Mura, ... Cardiovascular research 113 (5), 531-541, 2017 | 127 | 2017 |
Antisense‐mediated exon skipping: a therapeutic strategy for titin‐based dilated cardiomyopathy M Gramlich, LS Pane, Q Zhou, Z Chen, M Murgia, S Schötterl, A Goedel, ... EMBO molecular medicine 7 (5), 562-576, 2015 | 125 | 2015 |
Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity T Dorn, A Goedel, JT Lam, J Haas, Q Tian, F Herrmann, K Bundschu, ... Stem cells 33 (4), 1113-1129, 2015 | 117 | 2015 |
Pluripotent stem cell models of human heart disease A Moretti, KL Laugwitz, T Dorn, D Sinnecker, C Mummery Cold Spring Harbor Perspectives in Medicine 3 (11), a014027, 2013 | 111 | 2013 |
Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes Z Chen, W Xian, M Bellin, T Dorn, Q Tian, A Goedel, L Dreizehnter, ... European Heart Journal 38 (4), 292-301, 2017 | 101 | 2017 |
Induced pluripotent stem cell-derived cardiomyocytes for drug development and toxicity testing D Sinnecker, KL Laugwitz, A Moretti Pharmacology & therapeutics 143 (2), 246-252, 2014 | 101 | 2014 |
Change in left ventricular ejection fraction following first myocardial infarction and outcome DS Chew, H Heikki, G Schmidt, KM Kavanagh, M Dommasch, ... JACC: Clinical Electrophysiology 4 (5), 672-682, 2018 | 88 | 2018 |
Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates cardiomyocyte identity T Dorn, J Kornherr, EI Parrotta, D Zawada, H Ayetey, G Santamaria, L Iop, ... The EMBO journal 37 (12), e98133, 2018 | 79 | 2018 |
Induced pluripotent stem cell-derived cardiomyocytes: a versatile tool for arrhythmia research D Sinnecker, A Goedel, KL Laugwitz, A Moretti Circulation Research 112 (6), 961-968, 2013 | 56 | 2013 |
Effects of smoking status, history and intensity on heart rate variability in the general population: The CHRIS study F Murgia, R Melotti, L Foco, M Gögele, V Meraviglia, B Motta, A Steger, ... PloS one 14 (4), e0215053, 2019 | 51 | 2019 |
Sequential defects in cardiac lineage commitment and maturation cause hypoplastic left heart syndrome M Krane, M Dreßen, G Santamaria, I My, CM Schneider, T Dorn, S Laue, ... Circulation 144 (17), 1409-1428, 2021 | 40 | 2021 |
In-silico assessment of the dynamic effects of amiodarone and dronedarone on human atrial patho-electrophysiology A Loewe, Y Lutz, M Wilhelms, D Sinnecker, P Barthel, EP Scholz, ... Europace 16 (suppl_4), iv30-iv38, 2014 | 35 | 2014 |
Genetically encoded voltage indicators in circulation research L Kaestner, Q Tian, E Kaiser, W Xian, A Müller, M Oberhofer, ... International Journal of Molecular Sciences 16 (9), 21626-21642, 2015 | 33 | 2015 |
Modeling long-QT syndromes with iPS cells D Sinnecker, A Goedel, T Dorn, RJ Dirschinger, A Moretti, KL Laugwitz Journal of cardiovascular translational research 6, 31-36, 2013 | 32 | 2013 |
Expiration-triggered sinus arrhythmia predicts outcome in survivors of acute myocardial infarction D Sinnecker, M Dommasch, A Steger, A Berkefeld, P Hoppmann, A Müller, ... Journal of the American College of Cardiology 67 (19), 2213-2220, 2016 | 30 | 2016 |
Impact of sympathetic renal denervation: a randomized study in patients after renal transplantation (ISAR-denerve) S Schneider, D Promny, D Sinnecker, RA Byrne, A Müller, M Dommasch, ... Nephrology Dialysis Transplantation 30 (11), 1928-1936, 2015 | 30 | 2015 |