| SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T … JM Chemnitz, RV Parry, KE Nichols, CH June, JL Riley The Journal of Immunology 173 (2), 945-954, 2004 | 1555 | 2004 |
| Germline mutations in predisposition genes in pediatric cancer J Zhang, MF Walsh, G Wu, MN Edmonson, TA Gruber, J Easton, ... New England Journal of Medicine 373 (24), 2336-2346, 2015 | 1248 | 2015 |
| Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing AL Jackson, J Burchard, D Leake, A Reynolds, J Schelter, J Guo, ... Rna 12 (7), 1197-1205, 2006 | 1062 | 2006 |
| 2016 classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American College of … A Ravelli, F Minoia, S Davì, AC Horne, F Bovis, A Pistorio, M Aricò, ... Arthritis & rheumatology 68 (3), 566-576, 2016 | 878 | 2016 |
| Recommendations for the management of hemophagocytic lymphohistiocytosis in adults P La Rosée, AC Horne, M Hines, T von Bahr Greenwood, R Machowicz, ... Blood, The Journal of the American Society of Hematology 133 (23), 2465-2477, 2019 | 823 | 2019 |
| Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy DT Teachey, SR Rheingold, SL Maude, G Zugmaier, DM Barrett, AE Seif, ... Blood, The Journal of the American Society of Hematology 121 (26), 5154-5157, 2013 | 673 | 2013 |
| The immunology of macrophage activation syndrome CB Crayne, S Albeituni, KE Nichols, RQ Cron Frontiers in immunology 10, 119, 2019 | 631 | 2019 |
| Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1 KE Nichols, JD Crispino, M Poncz, JG White, SH Orkin, JM Maris, ... Nature genetics 24 (3), 266-270, 2000 | 618 | 2000 |
| Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome KE Nichols, DP Harkin, S Levitz, M Krainer, KA Kolquist, C Genovese, ... Proceedings of the National Academy of Sciences 95 (23), 13765-13770, 1998 | 577 | 1998 |
| Regulation of NKT cell development by SAP, the protein defective in XLP KE Nichols, J Hom, SY Gong, A Ganguly, CS Ma, JL Cannons, ... Nature medicine 11 (3), 340-345, 2005 | 463 | 2005 |
| Germ-line p53 Mutations Predispose to a Wide Spectrum of Early-onset Cancers KE Nichols, D Malkin, JE Garber, JF Fraumeni Jr, FP Li Cancer Epidemiology Biomarkers & Prevention 10 (2), 83-87, 2001 | 431 | 2001 |
| Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D B Chaigne-Delalande, FY Li, GM O’Connor, MJ Lukacs, P Jiang, L Zheng, ... Science 341 (6142), 186-191, 2013 | 370 | 2013 |
| X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease C Booth, KC Gilmour, P Veys, AR Gennery, MA Slatter, H Chapel, ... Blood, The Journal of the American Society of Hematology 117 (1), 53-62, 2011 | 352 | 2011 |
| Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules CS Ma, KE Nichols, SG Tangye Annu. Rev. Immunol. 25 (1), 337-379, 2007 | 325 | 2007 |
| Challenges in the diagnosis of hemophagocytic lymphohistiocytosis: recommendations from the North American Consortium for Histiocytosis (NACHO) MB Jordan, CE Allen, J Greenberg, M Henry, ML Hermiston, A Kumar, ... Pediatric blood & cancer 66 (11), e27929, 2019 | 319 | 2019 |
| Cutting edge: functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome SG Tangye, JH Phillips, LL Lanier, KE Nichols The Journal of Immunology 165 (6), 2932-2936, 2000 | 302 | 2000 |
| SAP regulates TH2 differentiation and PKC-θ-mediated activation of NF-κB1 JL Cannons, JY Li, B Hill, LA Mijares, D Dombroski, KE Nichols, ... Immunity 21 (5), 693-706, 2004 | 299 | 2004 |
| The genetic basis and cell of origin of mixed phenotype acute leukaemia TB Alexander, Z Gu, I Iacobucci, K Dickerson, JK Choi, B Xu, ... Nature 562 (7727), 373-379, 2018 | 295 | 2018 |
| CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A LM Shlapatska, SV Mikhalap, AG Berdova, OM Zelensky, TJ Yun, ... The Journal of Immunology 166 (9), 5480-5487, 2001 | 289 | 2001 |
| Treatment of E pstein B arr virus‐induced haemophagocytic lymphohistiocytosis with rituximab‐containing chemo‐immunotherapeutic regimens DB Chellapandian, R Das, K Zelley, SJ Wiener, H Zhao, DT Teachey, ... British journal of haematology 162 (3), 376-382, 2013 | 275 | 2013 |
