Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity O El-Kabbani, V Carbone, C Darmanin, M Oka, A Mitschler, A Podjarny, ... Journal of medicinal chemistry 48 (17), 5536-5542, 2005 | 84 | 2005 |
Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling M Stefek, V Snirc, PO Djoubissie, M Majekova, V Demopoulos, L Rackova, ... Bioorganic & medicinal chemistry 16 (9), 4908-4920, 2008 | 77 | 2008 |
Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease G Evin, RA Sharples, A Weidemann, FBM Reinhard, V Carbone, ... Biochemistry 40 (28), 8359-8368, 2001 | 52 | 2001 |
A1Ao-ATP synthase of Methanobrevibacter ruminantium couples sodium ions for ATP synthesis under physiological conditions DGG McMillan, SA Ferguson, D Dey, K Schröder, HL Aung, V Carbone, ... Journal of Biological Chemistry 286 (46), 39882-39892, 2011 | 47 | 2011 |
Drug–drug plasma protein binding interactions of ivacaftor EK Schneider, JX Huang, V Carbone, M Baker, MAK Azad, MA Cooper, ... Journal of Molecular Recognition 28 (6), 339-348, 2015 | 46 | 2015 |
Structure of aldehyde reductase in ternary complex with a 5-arylidene-2, 4-thiazolidinedione aldose reductase inhibitor V Carbone, M Giglio, R Chung, T Huyton, J Adams, R Maccari, R Ottana, ... European journal of medicinal chemistry 45 (3), 1140-1145, 2010 | 41 | 2010 |
A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20α-hydroxysteroid dehydrogenase U Dhagat, V Carbone, RPT Chung, T Matsunaga, S Endo, A Hara, ... Medicinal Chemistry 3 (6), 546-550, 2007 | 35 | 2007 |
The potentially beneficial central nervous system activity profile of ivacaftor and its metabolites EK Schneider, RM McQuade, VC Carbone, F Reyes-Ortega, JW Wilson, ... ERJ open research 4 (1), 2018 | 31 | 2018 |
Characterization of two isoforms of mouse 3 (17) α-hydroxysteroid dehydrogenases of the aldo-keto reductase family S Ishikura, N Usami, S Nakajima, A Kameyama, H Shiraishi, V Carbone, ... Biological and Pharmaceutical Bulletin 27 (12), 1939-1945, 2004 | 31 | 2004 |
Structural and functional features of dimeric dihydrodiol dehydrogenase V Carbone, A Hara, O El-Kabbani Cellular and Molecular Life Sciences 65, 1464-1474, 2008 | 30 | 2008 |
Crystal structure of human L‐xylulose reductase holoenzyme: Probing the role of Asn107 with site‐directed mutagenesis O El‐Kabbani, S Ishikura, C Darmanin, V Carbone, RPT Chung, N Usami, ... Proteins: Structure, Function, and Bioinformatics 55 (3), 724-732, 2004 | 30 | 2004 |
Structure and evolution of the archaeal lipid synthesis enzyme sn-glycerol-1-phosphate dehydrogenase V Carbone, LR Schofield, Y Zhang, C Sang, D Dey, IM Hannus, WF Martin, ... Journal of Biological Chemistry 290 (35), 21690-21704, 2015 | 29 | 2015 |
Interaction of phthalates and phenoxy acid herbicide environmental pollutants with intestinal intracellular lipid binding proteins V Carbone, T Velkov Chemical Research in Toxicology 26 (8), 1240-1250, 2013 | 29 | 2013 |
Plasma Protein Binding Structure–Activity Relationships Related to the N-Terminus of Daptomycin TV Elena K. Schneider, Johnny X. Huang, Vincenzo Carbone, Meiling Han, Yan ... Infectious Diseases 3 (3), 249-258, 2017 | 28* | 2017 |
Development of Multiwell-Plate Methods Using Pure Cultures of Methanogens To Identify New Inhibitors for Suppressing Ruminant Methane Emissions. CGM Weimar MR, Cheung J, Dey D, McSweeney C, Morrison M, Kobayashi Y ... Applied and Environmental Microbiology 83 (15), 1-17, 2017 | 26* | 2017 |
Correlation of binding constants and molecular modelling of inhibitors in the active sites of aldose reductase and aldehyde reductase V Carbone, HT Zhao, R Chung, S Endo, A Hara, O El-Kabbani Bioorganic & medicinal chemistry 17 (3), 1244-1250, 2009 | 25 | 2009 |
Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking V Carbone, S Ishikura, A Hara, O El-Kabbani Bioorganic & medicinal chemistry 13 (2), 301-312, 2005 | 25 | 2005 |
Structure of the tetrameric form of human L‐Xylulose reductase: Probing the inhibitor‐binding site with molecular modeling and site‐directed mutagenesis O El‐Kabbani, V Carbone, C Darmanin, S Ishikura, A Hara Proteins: Structure, Function, and Bioinformatics 60 (3), 424-432, 2005 | 24 | 2005 |
Enzymatic characteristics of an aldo–keto reductase family protein (AKR1C15) and its localization in rat tissues S Endo, T Matsunaga, K Horie, K Tajima, Y Bunai, V Carbone, ... Archives of biochemistry and biophysics 465 (1), 136-147, 2007 | 22 | 2007 |
The RNA-dependent-RNA polymerase, an emerging antiviral drug target for the Hendra virus T Velkov, V Carbone, J Akter, S Sivanesan, J Li, T Beddoe, G A Marsh Current drug targets 15 (1), 103-113, 2014 | 18 | 2014 |