| A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62 A Lau, XJ Wang, F Zhao, NF Villeneuve, T Wu, T Jiang, Z Sun, E White, ... Molecular and cellular biology 30 (13), 3275-3285, 2010 | 885 | 2010 |
| Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism D Ren, NF Villeneuve, T Jiang, T Wu, A Lau, HA Toppin, DD Zhang Proceedings of the National Academy of Sciences 108 (4), 1433-1438, 2011 | 674 | 2011 |
| Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis T Wu, F Zhao, B Gao, C Tan, N Yagishita, T Nakajima, PK Wong, ... Genes & development 28 (7), 708-722, 2014 | 343 | 2014 |
| PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function J Ma, H Cai, T Wu, B Sobhian, Y Huo, A Alcivar, M Mehta, KL Cheung, ... Molecular and cellular biology 32 (8), 1506-1517, 2012 | 224 | 2012 |
| Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention DDZ Bryan Harder, Tao Jiang, Tongde Wu, Shasha Tao, Montserrat Rojo de la ... Biochemical Society Transactions 43 (4), 680-686, 2015 | 181 | 2015 |
| KPNA6 (Importin α7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response Z Sun, T Wu, F Zhao, A Lau, CM Birch, DD Zhang Molecular and cellular biology, 2011 | 135 | 2011 |
| Nrf2 promotes neuronal cell differentiation F Zhao, T Wu, A Lau, T Jiang, Z Huang, XJ Wang, W Chen, PK Wong, ... Free Radical Biology and Medicine 47 (6), 867-879, 2009 | 123 | 2009 |
| USP15 negatively regulates Nrf2 through deubiquitination of Keap1 NF Villeneuve, W Tian, T Wu, Z Sun, A Lau, E Chapman, D Fang, ... Molecular cell 51 (1), 68-79, 2013 | 120 | 2013 |
| Oxidative stress, mammospheres and Nrf2–new implication for breast cancer therapy? T Wu, BG Harder, PK Wong, JE Lang, DD Zhang Molecular carcinogenesis 54 (11), 1494-1502, 2015 | 112 | 2015 |
| p97 negatively regulates NRF2 by extracting ubiquitylated NRF2 from the KEAP1-CUL3 E3 complex S Tao, P Liu, G Luo, M Rojo de la Vega, H Chen, T Wu, J Tillotson, ... Molecular and cellular biology 37 (8), e00660-16, 2017 | 95 | 2017 |
| Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor T Wu, J Huang, PJ Moore, MS Little, WG Walton, RC Fellner, NE Alexis, ... Nature communications 8 (1), 14118, 2017 | 54 | 2017 |
| Poly (ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription T Wu, XJ Wang, W Tian, MC Jaramillo, A Lau, DD Zhang Free Radical Biology and Medicine 67, 69-80, 2014 | 54 | 2014 |
| Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA (III)]-induced malignant transformation of urothelial cells C Escudero-Lourdes, T Wu, JM Camarillo, AJ Gandolfi Toxicology and applied pharmacology, 2011 | 46 | 2011 |
| Withaferin A analogs that target the AAA+ chaperone p97 S Tao, J Tillotson, EMK Wijeratne, Y Xu, MJ Kang, T Wu, EC Lau, C Mesa, ... ACS chemical biology 10 (8), 1916-1924, 2015 | 44 | 2015 |
| SPLUNC1 is an allosteric modulator of the epithelial sodium channel CS Kim, S Ahmad, T Wu, WG Walton, MR Redinbo, R Tarran The FASEB Journal 32 (5), 2478, 2018 | 38 | 2018 |
| Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action MJ Kang, T Wu, EMK Wijeratne, EC Lau, DJ Mason, C Mesa, J Tillotson, ... ChemBioChem 15 (14), 2125-2131, 2014 | 30 | 2014 |
| Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene MJ Canet, MD Merrell, BG Harder, JM Maher, T Wu, AJ Lickteig, ... Drug Metabolism and Disposition 43 (1), 93-99, 2015 | 25 | 2015 |
| A SPLUNC1 peptidomimetic inhibits Orai1 and reduces inflammation in a murine allergic asthma model JA Wrennall, S Ahmad, EN Worthington, T Wu, AS Goriounova, ... American Journal of Respiratory Cell and Molecular Biology 66 (3), 271-282, 2022 | 21 | 2022 |
| JUUL e-liquid exposure elicits cytoplasmic Ca2+ responses and leads to cytotoxicity in cultured airway epithelial cells R Zhang, MM Jones, RE Dornsife, T Wu, V Sivaraman, R Tarran, ... Toxicology letters 337, 46-56, 2021 | 15 | 2021 |
| Involvement of PU. 1 in mouse adar-1 gene transcription induced by high-dose esiRNA T Wu, Y Zhao, Z Hao, H Zhao, W Wang International journal of biological macromolecules 45 (2), 157-162, 2009 | 7 | 2009 |
