Helicobacter exploits integrin for type IV secretion and kinase activation T Kwok, D Zabler, S Urman, M Rohde, R Hartig, S Wessler, R Misselwitz, ... Nature 449 (7164), 862-866, 2007 | 745 | 2007 |
A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and … M Lorenz, S Wessler, E Follmann, W Michaelis, T Düsterhöft, ... Journal of Biological Chemistry 279 (7), 6190-6195, 2004 | 442 | 2004 |
Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E‐cadherin to disrupt intercellular adhesion B Hoy, M Löwer, C Weydig, G Carra, N Tegtmeyer, T Geppert, P Schröder, ... EMBO reports 11 (10), 798-804, 2010 | 331 | 2010 |
Role of the cag‐pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis N Tegtmeyer, S Wessler, S Backert The FEBS journal 278 (8), 1190-1202, 2011 | 322 | 2011 |
Phosphorylation of Helicobacter pylori CagA by c-Abl leads to cell motility M Poppe, SM Feller, G Römer, S Wessler Oncogene 26 (24), 3462-3472, 2007 | 260 | 2007 |
c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains D Mueller, N Tegtmeyer, S Brandt, Y Yamaoka, E De Poire, D Sgouras, ... The Journal of clinical investigation 122 (4), 1553-1566, 2012 | 256 | 2012 |
Activation of activator protein 1 and stress response kinases in epithelial cells colonized by Helicobacter pylori encoding the cag pathogenicity island M Naumann, S Wessler, C Bartsch, B Wieland, A Covacci, R Haas, ... Journal of Biological Chemistry 274 (44), 31655-31662, 1999 | 237 | 1999 |
The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis G Posselt, S Backert, S Wessler Cell Communication and Signaling 11, 1-14, 2013 | 223 | 2013 |
Distinct roles of secreted HtrA proteases from gram-negative pathogens in cleaving the junctional protein and tumor suppressor E-cadherin B Hoy, T Geppert, M Boehm, F Reisen, P Plattner, G Gadermaier, ... Journal of Biological Chemistry 287 (13), 10115-10120, 2012 | 188 | 2012 |
Neisseria gonorrhoeae Epithelial Cell Interaction Leads to the Activation of the Transcription Factors Nuclear Factor κB and Activator Protein 1 and the Induction of … M Naumann, S Weßler, C Bartsch, B Wieland, TF Meyer The Journal of experimental medicine 186 (2), 247-258, 1997 | 175 | 1997 |
Helicobacter pylori employs a unique basolateral type IV secretion mechanism for CagA delivery N Tegtmeyer, S Wessler, V Necchi, M Rohde, A Harrer, TT Rau, CI Asche, ... Cell host & microbe 22 (4), 552-560. e5, 2017 | 160 | 2017 |
Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin … M Boehm, B Hoy, M Rohde, N Tegtmeyer, KT Bæk, OA Oyarzabal, ... Gut pathogens 4, 1-12, 2012 | 155 | 2012 |
Molecular mechanisms of epithelial-barrier disruption by Helicobacter pylori S Wessler, S Backert Trends in microbiology 16 (8), 397-405, 2008 | 150 | 2008 |
Transmigration route of Campylobacter jejuni across polarized intestinal epithelial cells: paracellular, transcellular or both? S Backert, M Boehm, S Wessler, N Tegtmeyer Cell Communication and Signaling 11, 1-15, 2013 | 141 | 2013 |
Extracellular HtrA serine proteases: an emerging new strategy in bacterial pathogenesis S Backert, S Bernegger, J Skórko‐Glonek, S Wessler Cellular Microbiology 20 (6), e12845, 2018 | 118 | 2018 |
Helicobacter pylori CagL dependent induction of gastrin expression via a novel αvβ5-integrin–integrin linked kinase signalling complex T Wiedemann, S Hofbaur, N Tegtmeyer, S Huber, N Sewald, S Wessler, ... Gut 61 (7), 986-996, 2012 | 117 | 2012 |
Helicobacter pylori stimulates host cyclooxygenase‐2 gene transcription: critical importance of MEK/ERK‐dependent activation of USF1/‐2 and CREB transcription … S Jüttner, T Cramer, S Wessler, A Walduck, F Gao, F Schmitz, C Wunder, ... Cellular microbiology 5 (11), 821-834, 2003 | 102 | 2003 |
Prediction of Extracellular Proteases of the Human Pathogen Helicobacter pylori Reveals Proteolytic Activity of the Hp1018/19 Protein HtrA M Löwer, C Weydig, D Metzler, A Reuter, A Starzinski-Powitz, S Wessler, ... PloS one 3 (10), e3510, 2008 | 99 | 2008 |
Emerging roles of Abl family tyrosine kinases in microbial pathogenesis S Backert, SM Feller, S Wessler Trends in biochemical sciences 33 (2), 80-90, 2008 | 95 | 2008 |
p120 and Kaiso Regulate Helicobacter pylori-induced Expression of Matrix Metalloproteinase-7 SR Ogden, LE Wroblewski, C Weydig, J Romero-Gallo, DP O'Brien, ... Molecular biology of the cell 19 (10), 4110-4121, 2008 | 93 | 2008 |