Biosynthesis, purification, and substrate specificity of severe acute respiratory syndrome coronavirus 3C-like proteinase K Fan, P Wei, Q Feng, S Chen, C Huang, L Ma, B Lai, J Pei, Y Liu, J Chen, ... Journal of Biological Chemistry 279 (3), 1637-1642, 2004 | 375 | 2004 |
3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism C Huang, P Wei, K Fan, Y Liu, L Lai Biochemistry 43 (15), 4568-4574, 2004 | 223 | 2004 |
Rapid diversification of cell signaling phenotypes by modular domain recombination SG Peisajovich, JE Garbarino, P Wei, WA Lim Science 328 (5976), 368-372, 2010 | 188 | 2010 |
Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors L Zhou, Y Liu, W Zhang, P Wei, C Huang, J Pei, Y Yuan, L Lai Journal of Medicinal Chemistry 49 (12), 3440-3443, 2006 | 168 | 2006 |
Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells P Wei, WW Wong, JS Park, EE Corcoran, SG Peisajovich, JJ Onuffer, ... Nature 488 (7411), 384, 2012 | 149 | 2012 |
Only one protomer is active in the dimer of SARS 3C-like proteinase H Chen, P Wei, C Huang, L Tan, Y Liu, L Lai Journal of Biological Chemistry 281 (20), 13894-13898, 2006 | 119 | 2006 |
Oscillatory stress stimulation uncovers an Achilles’ heel of the yeast MAPK signaling network A Mitchell, P Wei, WA Lim Science 350 (6266), 1379-1383, 2015 | 114 | 2015 |
Chimeric antigen receptor designed to prevent ubiquitination and downregulation showed durable antitumor efficacy W Li, S Qiu, J Chen, S Jiang, W Chen, J Jiang, F Wang, W Si, Y Shu, ... Immunity 53 (2), 456-470. e6, 2020 | 110 | 2020 |
The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase P Wei, K Fan, H Chen, L Ma, C Huang, L Tan, D Xi, C Li, Y Liu, A Cao, ... Biochemical and biophysical research communications 339 (3), 865-872, 2006 | 104 | 2006 |
Virtual screening of novel noncovalent inhibitors for SARS-CoV 3C-like proteinase Z Liu, C Huang, K Fan, P Wei, H Chen, S Liu, J Pei, L Shi, B Li, K Yang, ... Journal of chemical information and modeling 45 (1), 10-17, 2005 | 92 | 2005 |
The substrate specificity of SARS coronavirus 3C-like proteinase K Fan, L Ma, X Han, H Liang, P Wei, Y Liu, L Lai Biochemical and biophysical research communications 329 (3), 934-940, 2005 | 88 | 2005 |
Differential genetic interactions of yeast stress response MAPK pathways H Martin, M Shales, P Fernandez‐Piñar, P Wei, M Molina, D Fiedler, ... Molecular systems biology 11 (4), 800, 2015 | 62 | 2015 |
Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase C Li, Y Qi, X Teng, Z Yang, P Wei, C Zhang, L Tan, L Zhou, Y Liu, L Lai Journal of biological chemistry 285 (36), 28134-28140, 2010 | 61 | 2010 |
De novo design of a βαβ motif H Liang, H Chen, K Fan, P Wei, X Guo, C Jin, C Zeng, C Tang, L Lai Angewandte Chemie International Edition 48 (18), 3301-3303, 2009 | 61 | 2009 |
Cas9 exo-endonuclease eliminates chromosomal translocations during genome editing J Yin, R Lu, C Xin, Y Wang, X Ling, D Li, W Zhang, M Liu, W Xie, L Kong, ... Nature communications 13 (1), 1204, 2022 | 59 | 2022 |
Design of tunable oscillatory dynamics in a synthetic NF-κB signaling circuit ZB Zhang, QY Wang, YX Ke, SY Liu, JQ Ju, WA Lim, C Tang, P Wei Cell systems 5 (5), 460-470. e5, 2017 | 45 | 2017 |
Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase L Lai, X Han, H Chen, P Wei, C Huang, S Liu, K Fan, L Zhou, Z Liu, J Pei, ... Current pharmaceutical design 12 (35), 4555-4564, 2006 | 44 | 2006 |
The interaction between severe acute respiratory syndrome coronavirus 3C-like proteinase and a dimeric inhibitor by capillary electrophoresis L Ding, XX Zhang, P Wei, K Fan, L Lai Analytical biochemistry 343 (1), 159-165, 2005 | 41 | 2005 |
Synthetic immunology: T-cell engineering and adoptive immunotherapy W Si, C Li, P Wei Synthetic and systems biotechnology 3 (3), 179-185, 2018 | 37 | 2018 |
Cell cycle inhibitor Whi5 records environmental information to coordinate growth and division in yeast Y Qu, J Jiang, X Liu, P Wei, X Yang, C Tang Cell reports 29 (4), 987-994. e5, 2019 | 36 | 2019 |