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Nirmalya Saha
Nirmalya Saha
Research Lab Specialist Senior at University of Michigan
在 med.umich.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3
A Gajan, VL Barnes, M Liu, N Saha, LA Pile
Epigenetics & chromatin 9, 1-23, 2016
442016
The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia
J Serio, J Ropa, W Chen, M Mysliwski, N Saha, L Chen, J Wang, H Miao, ...
Oncogene 37 (4), 450-460, 2018
432018
Integration of CRISPR/Cas9 with artificial intelligence for improved cancer therapeutics
AA Bhat, S Nisar, S Mukherjee, N Saha, N Yarravarapu, SN Lone, ...
Journal of translational medicine 20 (1), 534, 2022
362022
Genome-wide studies reveal novel and distinct biological pathways regulated by SIN3 isoforms
N Saha, M Liu, A Gajan, LA Pile
BMC genomics 17, 1-16, 2016
362016
Insight into the multi-faceted role of the SUV family of H3K9 methyltransferases in carcinogenesis and cancer progression
N Saha, AG Muntean
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1875 (1), 188498, 2021
332021
SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation
J Ropa, N Saha, H Hu, LF Peterson, M Talpaz, AG Muntean
Haematologica 105 (9), 2273, 2019
332019
PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia
J Ropa, N Saha, Z Chen, J Serio, W Chen, D Mellacheruvu, L Zhao, ...
Oncotarget 9 (31), 22123, 2018
332018
A complex interplay between SAM synthetase and the epigenetic regulator SIN3 controls metabolism and transcription
M Liu, N Saha, A Gajan, N Saadat, SV Gupta, LA Pile
Journal of Biological Chemistry 295 (2), 375-389, 2020
162020
The PAF1c subunit CDC73 is required for mouse hematopoietic stem cell maintenance but displays leukemia-specific gene regulation
N Saha, J Ropa, L Chen, H Hu, M Mysliwski, A Friedman, I Maillard, ...
Stem Cell Reports 12 (5), 1069-1083, 2019
162019
The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t (11; 19) Leukemia
H Hu, N Saha, Y Yang, E Ahmad, L Lachowski, U Shrestha, V Premkumar, ...
Leukemia 37 (1), 190-201, 2023
92023
The PAF1c Subunit Cdc73 Is Essential for Hematopoiesis and Displays Differential Gene Regulation in MLL-AF9 Driven Leukemia
S Nirmalya, J Ropa, L Chen, HY Hu, M Mysliwski, A Friedman, I Maillard, ...
Blood 132, 1280, 2018
12018
Investigating the Role of the SETDB1 Target TANGO6 (TMCO7) in Leukemia
J Pruitt, N Saha, L Lachowski, AG Muntean
Blood 142, 5695, 2023
2023
Understanding leukemia biology using genome editing techniques
S Jimenez-Morales, K Banerjee, N Saha, A Basu, KL McGraw
Frontiers in Oncology 13, 1323584, 2023
2023
The ENL YEATS domain links leukemic stem cell frequency and enhances YEATS inhibitor sensitivity in MLL-ENL leukemias
H Hu, N Saha, Y Yang, E Ahmad, L Lachowski, U Shrestha, V Premkumar, ...
Cancer Research 83 (7_Supplement), 3550-3550, 2023
2023
The epigenetic reader function of the YEATS domain in MLL-ENL fusion critically affects leukemic stem cell frequency in MLL-ENL leukemia
H Hu, N Saha, E Ahmad, Y Yang, L Chen, L Lachowski, B Teahan, ...
Cancer Research 82 (12_Supplement), 2966-2966, 2022
2022
Investigating the Roles of the Yeats Domain in MLL-ENL Mediated Leukemogenesis
H Hu, N Saha, Y Yang, SM Grigsby, R Marschalek, Z Nikolovska-Coleska, ...
Blood 136, 30-31, 2020
2020
SETDB1 Mediated H3K9 Methylation Suppresses MLL-Fusion Target Expression and Leukemic Transformation
AG Muntean, J Ropa, S Nirmalya, HY Hu, J Serio, L Zhao, V Basrur, ...
Blood 134, 110, 2019
2019
SETDB1 Represses Hox Gene Expression and Suppresses Acute Myeloid Leukemia
J Ropa, S Nirmalya, AG Muntean
Blood 132, 1320, 2018
2018
Functional anaysis of SIN3 isoforms in Drosophila
N Saha
Wayne State University, 2017
2017
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