The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3 A Gajan, VL Barnes, M Liu, N Saha, LA Pile Epigenetics & chromatin 9, 1-23, 2016 | 44 | 2016 |
The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia J Serio, J Ropa, W Chen, M Mysliwski, N Saha, L Chen, J Wang, H Miao, ... Oncogene 37 (4), 450-460, 2018 | 43 | 2018 |
Integration of CRISPR/Cas9 with artificial intelligence for improved cancer therapeutics AA Bhat, S Nisar, S Mukherjee, N Saha, N Yarravarapu, SN Lone, ... Journal of translational medicine 20 (1), 534, 2022 | 36 | 2022 |
Genome-wide studies reveal novel and distinct biological pathways regulated by SIN3 isoforms N Saha, M Liu, A Gajan, LA Pile BMC genomics 17, 1-16, 2016 | 36 | 2016 |
Insight into the multi-faceted role of the SUV family of H3K9 methyltransferases in carcinogenesis and cancer progression N Saha, AG Muntean Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1875 (1), 188498, 2021 | 33 | 2021 |
SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation J Ropa, N Saha, H Hu, LF Peterson, M Talpaz, AG Muntean Haematologica 105 (9), 2273, 2019 | 33 | 2019 |
PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia J Ropa, N Saha, Z Chen, J Serio, W Chen, D Mellacheruvu, L Zhao, ... Oncotarget 9 (31), 22123, 2018 | 33 | 2018 |
A complex interplay between SAM synthetase and the epigenetic regulator SIN3 controls metabolism and transcription M Liu, N Saha, A Gajan, N Saadat, SV Gupta, LA Pile Journal of Biological Chemistry 295 (2), 375-389, 2020 | 16 | 2020 |
The PAF1c subunit CDC73 is required for mouse hematopoietic stem cell maintenance but displays leukemia-specific gene regulation N Saha, J Ropa, L Chen, H Hu, M Mysliwski, A Friedman, I Maillard, ... Stem Cell Reports 12 (5), 1069-1083, 2019 | 16 | 2019 |
The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t (11; 19) Leukemia H Hu, N Saha, Y Yang, E Ahmad, L Lachowski, U Shrestha, V Premkumar, ... Leukemia 37 (1), 190-201, 2023 | 9 | 2023 |
The PAF1c Subunit Cdc73 Is Essential for Hematopoiesis and Displays Differential Gene Regulation in MLL-AF9 Driven Leukemia S Nirmalya, J Ropa, L Chen, HY Hu, M Mysliwski, A Friedman, I Maillard, ... Blood 132, 1280, 2018 | 1 | 2018 |
Investigating the Role of the SETDB1 Target TANGO6 (TMCO7) in Leukemia J Pruitt, N Saha, L Lachowski, AG Muntean Blood 142, 5695, 2023 | | 2023 |
Understanding leukemia biology using genome editing techniques S Jimenez-Morales, K Banerjee, N Saha, A Basu, KL McGraw Frontiers in Oncology 13, 1323584, 2023 | | 2023 |
The ENL YEATS domain links leukemic stem cell frequency and enhances YEATS inhibitor sensitivity in MLL-ENL leukemias H Hu, N Saha, Y Yang, E Ahmad, L Lachowski, U Shrestha, V Premkumar, ... Cancer Research 83 (7_Supplement), 3550-3550, 2023 | | 2023 |
The epigenetic reader function of the YEATS domain in MLL-ENL fusion critically affects leukemic stem cell frequency in MLL-ENL leukemia H Hu, N Saha, E Ahmad, Y Yang, L Chen, L Lachowski, B Teahan, ... Cancer Research 82 (12_Supplement), 2966-2966, 2022 | | 2022 |
Investigating the Roles of the Yeats Domain in MLL-ENL Mediated Leukemogenesis H Hu, N Saha, Y Yang, SM Grigsby, R Marschalek, Z Nikolovska-Coleska, ... Blood 136, 30-31, 2020 | | 2020 |
SETDB1 Mediated H3K9 Methylation Suppresses MLL-Fusion Target Expression and Leukemic Transformation AG Muntean, J Ropa, S Nirmalya, HY Hu, J Serio, L Zhao, V Basrur, ... Blood 134, 110, 2019 | | 2019 |
SETDB1 Represses Hox Gene Expression and Suppresses Acute Myeloid Leukemia J Ropa, S Nirmalya, AG Muntean Blood 132, 1320, 2018 | | 2018 |
Functional anaysis of SIN3 isoforms in Drosophila N Saha Wayne State University, 2017 | | 2017 |