Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery KM Wasan, DR Brocks, SD Lee, K Sachs-Barrable, SJ Thornton Nature reviews Drug discovery 7 (1), 84-99, 2008 | 336 | 2008 |
Highly effective oral amphotericin B formulation against murine visceral leishmaniasis KM Wasan, EK Wasan, P Gershkovich, X Zhu, RR Tidwell, KA Werbovetz, ... Journal of Infectious Diseases 200 (3), 357-360, 2009 | 109 | 2009 |
Enhancing drug absorption using lipids: a case study presenting the development and pharmacological evaluation of a novel lipid-based oral amphotericin B formulation for the … K Sachs-Barrable, SD Lee, EK Wasan, SJ Thornton, KM Wasan Advanced drug delivery reviews 60 (6), 692-701, 2008 | 97 | 2008 |
Effects of forced diving on the spleen and hepatic sinus in northern elephant seal pups SJ Thornton, DM Spielman, NJ Pelc, WF Block, DE Crocker, DP Costa, ... Proceedings of the National Academy of Sciences 98 (16), 9413-9418, 2001 | 88 | 2001 |
A novel tropically stable oral amphotericin B formulation (iCo-010) exhibits efficacy against visceral Leishmaniasis in a murine model EK Wasan, P Gershkovich, J Zhao, X Zhu, K Werbovetz, RR Tidwell, ... PLoS neglected tropical diseases 4 (12), e913, 2010 | 65 | 2010 |
The Diving Response Mechanism and its Surprising Evolutionary Path in PD Mottishaw, SJ Thornton, PW Hochachka | 58* | 1999 |
The reformulation of amphotericin B for oral administration to treat systemic fungal infections and visceral leishmaniasis SJ Thornton, KM Wasan Expert opinion on drug delivery 6 (3), 271-284, 2009 | 54 | 2009 |
Barriers to treatment for visceral leishmaniasis in hyperendemic areas: India, Bangladesh, Nepal, Brazil and Sudan SJ Thornton, KM Wasan, A Piecuch, LLD Lynd, EK Wasan Drug development and industrial pharmacy 36 (11), 1312-1319, 2010 | 36 | 2010 |
Visceral leishmaniasis affects liver and spleen concentrations of amphotericin B following administration to mice P Gershkovich, EK Wasan, O Sivak, R Li, X Zhu, KA Werbovetz, ... Journal of antimicrobial chemotherapy 65 (3), 535-537, 2010 | 33 | 2010 |
Oxygen and the diving seal SJ Thornton, PW Hochachka Undersea Hyperb Med 31 (1), 81-95, 2004 | 32 | 2004 |
Proposed metrics for the management of underwater noise for southern resident killer whales K Heise, L Barrett-Lennard, R Chapman, T Dakin, C Erbe, DE Hannay, ... Coastal Ocean Report Series 2017, 2, 2017 | 27 | 2017 |
SYSTEMATIC SOURCE LEVEL MEASUREMENTS OF WHALE WATCHING VESSELS AND OTHER SMALL BOATS. JL Wladichuk, DE Hannay, AO MacGillivray, Z Li, SJ Thornton Journal of Ocean Technology 14 (3), 2019 | 25 | 2019 |
Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism SJ Thornton, E Wong, SD Lee, KM Wasan Lipids in Health and Disease 7, 1-7, 2008 | 24 | 2008 |
The global access initiative at the University of British Columbia (UBC): Availability of UBC discoveries and technologies to the developing world KM Wasan, SJ Thornton, I Bell, RE Goulding, M Gretes, AP Gray, ... Journal of pharmaceutical sciences 98 (3), 791-794, 2009 | 23 | 2009 |
Stroke volume and cardiac output in juvenile elephant seals during forced dives SJ Thornton, PW Hochachka, DE Crocker, DP Costa, BJ LeBoeuf, ... Journal of Experimental Biology 208 (19), 3637-3643, 2005 | 23 | 2005 |
The effects of experimentally induced hyperthyroidism on the diving physiology of harbor seals (Phoca vitulina) SJT GM Weingartner, RD Andrews, MR Enstipp, AD Barts, ... The physiological consequences of breath-hold diving in marine mammals; the …, 2012 | 17 | 2012 |
Treatment with a cholesterol absorption inhibitor (FM-VP4) reduces body mass and adipose accumulation in developing and pre-obese mice SJ Thornton, C Warburton, KM Wasan, P Kozlowski Drug development and industrial pharmacy 33 (10), 1058-1069, 2007 | 16 | 2007 |
Estimating animal utilization distributions from multiple data types: a joint spatiotemporal point process framework J Watson, R Joy, D Tollit, SJ Thornton, M Auger-Méthé The Annals of Applied Statistics 15 (4), 1872-1896, 2021 | 15 | 2021 |
Dietary supplementation with phytosterol and ascorbic acid reduces body mass accumulation and alters food transit time in a diet-induced obesity mouse model SJ Thornton, ITY Wong, R Neumann, P Kozlowski, KM Wasan Lipids in Health and Disease 10, 1-14, 2011 | 12 | 2011 |
Evaluation of the Contribution of the ATP Binding Cassette Transporter, P-glycoprotein, to in Vivo Cholesterol Homeostasis SD Lee, SJ Thornton, K Sachs-Barrable, JH Kim, KM Wasan Molecular pharmaceutics 10 (8), 3203-3212, 2013 | 10 | 2013 |