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Yongxu Lu
Yongxu Lu
Department of Pathology, Unviersity of Cambridge
在 cam.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease
Y Peng, SL Felce, D Dong, F Penkava, AJ Mentzer, X Yao, G Liu, Z Yin, ...
Nature immunology 23 (1), 50-61, 2022
1502022
How does vaccinia virus interfere with interferon?
GL Smith, C Talbot-Cooper, Y Lu
Advances in virus research 100, 355-378, 2018
702018
Vaccinia virus protein C6 inhibits type I IFN signalling in the nucleus and binds to the transactivation domain of STAT2
JH Stuart, RP Sumner, Y Lu, JS Snowden, GL Smith
PLoS pathogens 12 (12), e1005955, 2016
692016
Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6
Y Lu, JH Stuart, C Talbot-Cooper, S Agrawal-Singh, B Huntly, AI Smid, ...
Proceedings of the National Academy of Sciences 116 (24), 11997-12006, 2019
682019
Quantitative temporal proteomic analysis of vaccinia virus infection reveals regulation of histone deacetylases by an interferon antagonist
L Soday, Y Lu, JD Albarnaz, CTR Davies, R Antrobus, GL Smith, ...
Cell reports 27 (6), 1920-1933. e7, 2019
642019
The replication defect of ICP0-null mutant herpes simplex virus 1 can be largely complemented by the combined activities of human cytomegalovirus proteins IE1 and pp71
RD Everett, AJ Bell, Y Lu, A Orr
Journal of virology 87 (2), 978-990, 2013
362013
TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6
Y Zhao, Y Lu, S Richardson, M Sreekumar, JD Albarnaz, GL Smith
Nature 620 (7975), 873-880, 2023
202023
An overview of current knowledge of deadly CoVs and their interface with innate immunity
Y Zhang, S Gargan, Y Lu, NJ Stevenson
Viruses 13 (4), 560, 2021
202021
Stimulation of the replication of ICP0-null mutant herpes simplex virus 1 and pp71-deficient human cytomegalovirus by epstein-barr virus tegument protein BNRF1
Y Lu, A Orr, RD Everett
Journal of Virology 90 (21), 9664-9673, 2016
142016
Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins
Y Lu, HA Michel, PH Wang, GL Smith
Frontiers in Microbiology 13, 1027015, 2022
132022
DDX50 is a viral restriction factor that enhances IRF3 activation
MA Pallett, Y Lu, GL Smith
Viruses 14 (2), 316, 2022
132022
Analysis of the functional interchange between the IE1 and pp71 proteins of human cytomegalovirus and ICP0 of herpes simplex virus 1
Y Lu, RD Everett
Journal of Virology 89 (6), 3062-3075, 2015
122015
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
H Stewart, Y Lu, S O’Keefe, A Valpadashi, LD Cruz-Zaragoza, HA Michel, ...
Iscience 26 (11), 2023
102023
Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination
Z Yin, JL Chen, Y Lu, B Wang, L Godfrey, AJ Mentzer, X Yao, G Liu, ...
Cell Reports 42 (5), 2023
32023
HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus
Y Lu, Y Zhao, C Gao, S Suresh, J Men, A Sawyers, GL Smith
Cell Reports 43 (3), 2024
12024
The nuclear localization signal of monkeypox virus protein P2 orthologue is critical for inhibition of IRF3-mediated innate immunity
P Jiao, J Ma, Y Zhao, X Jia, H Zhang, W Fan, X Jia, X Bai, Y Zhao, Y Lu, ...
Emerging Microbes & Infections 13 (1), 2372344, 2024
2024
Filamin B restricts vaccinia virus spread and is targeted by vaccinia virus protein C4
I Georgana, SR Scutts, C Gao, Y Lu, AA Torres, H Ren, E Emmott, J Men, ...
Journal of Virology 98 (3), e01485-23, 2024
2024
DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation. Viruses 2022, 14, 316
MA Pallett, Y Lu, GL Smith
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2022
2022
An Overview of Current Knowledge of Deadly CoVs and Their Interface with Innate Immunity. Viruses 2021, 13, 560
Y Zhang, S Gargan, Y Lu, NJ Stevenson
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
2021
Inhibition of IFN-gamma signalling by vaccinia virus protein C6: a multi-functional interferon antagonist
C Talbot-Cooper, Y Lu, J Stewart, G Smith
Access Microbiology 1 (1A), 795, 2019
2019
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