| IFI16 is an innate immune sensor for intracellular DNA L Unterholzner, SE Keating, M Baran, KA Horan, SB Jensen, S Sharma, ... Nature immunology 11 (11), 997-1004, 2010 | 1859 | 2010 |
| Viral evasion and subversion of pattern-recognition receptor signalling AG Bowie, L Unterholzner Nature Reviews Immunology 8 (12), 911-922, 2008 | 901 | 2008 |
| Structures of the HIN domain: DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor T Jin, A Perry, J Jiang, P Smith, JA Curry, L Unterholzner, Z Jiang, ... Immunity 36 (4), 561-571, 2012 | 601 | 2012 |
| Non-canonical activation of the DNA sensing adaptor STING by ATM and IFI16 mediates NF-κB signaling after nuclear DNA damage G Dunphy, SM Flannery, JF Almine, DJ Connolly, C Paulus, KL Jønsson, ... Molecular cell 71 (5), 745-760. e5, 2018 | 539 | 2018 |
| Nonsense‐mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways D Gatfield, L Unterholzner, FD Ciccarelli, P Bork, E Izaurralde The EMBO journal, 2003 | 377 | 2003 |
| SMG7 acts as a molecular link between mRNA surveillance and mRNA decay L Unterholzner, E Izaurralde Molecular cell 16 (4), 587-596, 2004 | 371 | 2004 |
| IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes JF Almine, CAJ O’Hare, G Dunphy, IR Haga, RJ Naik, A Atrih, ... Nature communications 8 (1), 14392, 2017 | 330 | 2017 |
| The interferon response to intracellular DNA: why so many receptors? L Unterholzner Immunobiology 218 (11), 1312-1321, 2013 | 305 | 2013 |
| SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway N Fukuhara, J Ebert, L Unterholzner, D Lindner, E Izaurralde, E Conti Molecular cell 17 (4), 537-547, 2005 | 276 | 2005 |
| Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors KA Horan, K Hansen, MR Jakobsen, CK Holm, S Søby, L Unterholzner, ... The Journal of Immunology 190 (5), 2311-2319, 2013 | 230 | 2013 |
| Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7 L Unterholzner, RP Sumner, M Baran, H Ren, DS Mansur, NM Bourke, ... PLoS pathogens 7 (9), e1002247, 2011 | 192 | 2011 |
| The interplay between viruses and innate immune signaling: recent insights and therapeutic opportunities L Unterholzner, AG Bowie Biochemical pharmacology 75 (3), 589-602, 2008 | 166 | 2008 |
| Molecular insights into the interaction of PYM with the Mago–Y14 core of the exon junction complex F Bono, J Ebert, L Unterholzner, T Güttler, E Izaurralde, E Conti EMBO reports 5 (3), 304-310, 2004 | 135 | 2004 |
| Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence DS Mansur, C Maluquer de Motes, L Unterholzner, RP Sumner, ... PLoS pathogens 9 (2), e1003183, 2013 | 110 | 2013 |
| cGAS-independent STING activation in response to DNA damage L Unterholzner, G Dunphy Molecular & Cellular Oncology 6 (4), 1558682, 2019 | 40 | 2019 |
| Innate DNA sensing moves to the nucleus L Unterholzner, AG Bowie Cell host & microbe 9 (5), 351-353, 2011 | 28 | 2011 |
| Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7 L Gu, D Casserly, G Brady, S Carpenter, AP Bracken, KA Fitzgerald, ... Nature Communications 13 (1), 14, 2022 | 26 | 2022 |
| Camouflage and interception: how pathogens evade detection by intracellular nucleic acid sensors L Unterholzner, JF Almine Immunology 156 (3), 217-227, 2019 | 25 | 2019 |
| Structural mechanism of DNA recognition by the p204 HIN domain X Fan, J Jiang, D Zhao, F Chen, H Ma, P Smith, L Unterholzner, TS Xiao, ... Nucleic Acids Research 49 (5), 2959-2972, 2021 | 15 | 2021 |
| DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling OPG Wheeler, L Unterholzner Essays in Biochemistry 67 (6), 905-918, 2023 | 12 | 2023 |
