Signal-dependent dynamics of transcription factor translocation controls gene expression N Hao, EK O'shea Nature structural & molecular biology 19 (1), 31-39, 2012 | 324 | 2012 |
Regulation of cell signaling dynamics by the protein kinase-scaffold Ste5 N Hao, S Nayak, M Behar, RH Shanks, MJ Nagiec, B Errede, J Hasty, ... Molecular cell 30 (5), 649-656, 2008 | 168 | 2008 |
Tunable signal processing through modular control of transcription factor translocation N Hao, BA Budnik, J Gunawardena, EK O'Shea Science 339 (6118), 460-464, 2013 | 158 | 2013 |
Mathematical and computational analysis of adaptation via feedback inhibition in signal transduction pathways M Behar, N Hao, HG Dohlman, TC Elston Biophysical journal 93 (3), 806-821, 2007 | 140 | 2007 |
A systems-biology analysis of feedback inhibition in the Sho1 osmotic-stress-response pathway N Hao, M Behar, SC Parnell, MP Torres, CH Borchers, TC Elston, ... Current Biology 17 (8), 659-667, 2007 | 128 | 2007 |
Regulators of G protein signaling and transient activation of signaling: experimental and computational analysis reveals negative and positive feedback controls on G protein … N Hao, N Yildirim, Y Wang, TC Elston, HG Dohlman Journal of Biological Chemistry 278 (47), 46506-46515, 2003 | 108 | 2003 |
Bistability, stochasticity, and oscillations in the mitogen-activated protein kinase cascade X Wang, N Hao, HG Dohlman, TC Elston Biophysical journal 90 (6), 1961-1978, 2006 | 106 | 2006 |
High-throughput microfluidics to control and measure signaling dynamics in single yeast cells AS Hansen, N Hao, EK O'shea Nature protocols 10 (8), 1181-1197, 2015 | 104 | 2015 |
A programmable fate decision landscape underlies single-cell aging in yeast Y Li, Y Jiang, J Paxman, R O’Laughlin, S Klepin, Y Zhu, L Pillus, ... Science 369 (6501), 325-329, 2020 | 96 | 2020 |
A complex systems approach to aging biology AA Cohen, L Ferrucci, T Fülöp, D Gravel, N Hao, A Kriete, ME Levine, ... Nature Aging 2 (7), 580-591, 2022 | 91 | 2022 |
Multigenerational silencing dynamics control cell aging Y Li, M Jin, R O’Laughlin, P Bittihn, LS Tsimring, L Pillus, J Hasty, N Hao Proceedings of the National Academy of Sciences 114 (42), 11253-11258, 2017 | 86 | 2017 |
Control of MAPK specificity by feedback phosphorylation of shared adaptor protein Ste50 N Hao, Y Zeng, TC Elston, HG Dohlman Journal of Biological Chemistry 283 (49), 33798-33802, 2008 | 86 | 2008 |
Genome-Scale Analysis Reveals Sst2 as the Principal Regulator of Mating Pheromone Signaling in the Yeast Saccharomyces cerevisiae SA Chasse, P Flanary, SC Parnell, N Hao, JY Cha, DP Siderovski, ... Eukaryotic cell 5 (2), 330-346, 2006 | 83 | 2006 |
Dose-to-duration encoding and signaling beyond saturation in intracellular signaling networks M Behar, N Hao, HG Dohlman, TC Elston PLoS computational biology 4 (10), e1000197, 2008 | 70 | 2008 |
Divergent aging of isogenic yeast cells revealed through single-cell phenotypic dynamics M Jin, Y Li, R O’Laughlin, P Bittihn, L Pillus, LS Tsimring, J Hasty, N Hao Cell systems 8 (3), 242-253. e3, 2019 | 45 | 2019 |
Dynamic control of gene regulatory logic by seemingly redundant transcription factors Z AkhavanAghdam, J Sinha, OP Tabbaa, N Hao Elife 5, e18458, 2016 | 43 | 2016 |
Systems biology analysis of G protein and MAP kinase signaling in yeast N Hao, M Behar, TC Elston, HG Dohlman Oncogene 26 (22), 3254-3266, 2007 | 40 | 2007 |
Engineering longevity—design of a synthetic gene oscillator to slow cellular aging Z Zhou, Y Liu, Y Feng, S Klepin, LS Tsimring, L Pillus, J Hasty, N Hao Science 380 (6643), 376-381, 2023 | 25 | 2023 |
Mitogen-activated protein kinase (MAPK) dynamics determine cell fate in the yeast mating response Y Li, J Roberts, Z AkhavanAghdam, N Hao Journal of Biological Chemistry 292 (50), 20354-20361, 2017 | 24 | 2017 |
Combined computational and experimental analysis reveals mitogen-activated protein kinase–mediated feedback phosphorylation as a mechanism for signaling specificity N Hao, N Yildirim, MJ Nagiec, SC Parnell, B Errede, HG Dohlman, ... Molecular biology of the cell 23 (19), 3899-3910, 2012 | 24* | 2012 |