Clustering cancer gene expression data: a comparative study MCP De Souto, IG Costa, DS De Araujo, TB Ludermir, A Schliep BMC bioinformatics 9, 1-14, 2008 | 534 | 2008 |
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas JA Müller, R Groß, C Conzelmann, J Krüger, U Merle, J Steinhart, T Weil, ... Nature metabolism 3 (2), 149-165, 2021 | 492 | 2021 |
Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis O Krenkel, T Puengel, O Govaere, AT Abdallah, JC Mossanen, ... Hepatology 67 (4), 1270-1283, 2018 | 479 | 2018 |
Identification of transcription factor binding sites using ATAC-seq Z Li, MH Schulz, T Look, M Begemann, M Zenke, IG Costa Genome biology 20, 1-21, 2019 | 406 | 2019 |
Spatial multi-omic map of human myocardial infarction C Kuppe, RO Ramirez Flores, Z Li, S Hayat, RT Levinson, X Liao, ... Nature 608 (7924), 766-777, 2022 | 258 | 2022 |
Deep learning-based clustering approaches for bioinformatics MR Karim, O Beyan, A Zappa, IG Costa, D Rebholz-Schuhmann, ... Briefings in bioinformatics 22 (1), 393-415, 2021 | 231 | 2021 |
A multiple kernel learning algorithm for drug-target interaction prediction ACA Nascimento, RBC Prudêncio, IG Costa BMC bioinformatics 17, 1-16, 2016 | 229 | 2016 |
Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data D Dimitrov, D Türei, M Garrido-Rodriguez, PL Burmedi, JS Nagai, C Boys, ... Nature communications 13 (1), 3224, 2022 | 226* | 2022 |
Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling M Hohwieler, A Illing, PC Hermann, T Mayer, M Stockmann, L Perkhofer, ... Gut 66 (3), 473-486, 2017 | 222 | 2017 |
On the selection of appropriate distances for gene expression data clustering PA Jaskowiak, RJGB Campello, IG Costa BMC bioinformatics 15, 1-17, 2014 | 206 | 2014 |
DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy Q Lin, CI Weidner, IG Costa, RE Marioni, MRP Ferreira, IJ Deary, ... Aging (Albany NY) 8 (2), 394, 2016 | 189 | 2016 |
HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types A Zirkel, M Nikolic, K Sofiadis, JP Mallm, CA Brackley, H Gothe, ... Molecular cell 70 (4), 730-744. e6, 2018 | 187 | 2018 |
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 183 | 2022 |
Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis O Krenkel, J Hundertmark, AT Abdallah, M Kohlhepp, T Puengel, T Roth, ... Gut 69 (3), 551-563, 2020 | 173 | 2020 |
Analysis of computational footprinting methods for DNase sequencing experiments EG Gusmao, M Allhoff, M Zenke, IG Costa Nature methods 13 (4), 303-309, 2016 | 166 | 2016 |
The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation M Kalwa, S Hänzelmann, S Otto, CC Kuo, J Franzen, S Joussen, ... Nucleic acids research 44 (22), 10631-10643, 2016 | 161 | 2016 |
Detection of RNA–DNA binding sites in long noncoding RNAs CC Kuo, S Hänzelmann, N Sentürk Cetin, S Frank, B Zajzon, JP Derks, ... Nucleic acids research 47 (6), e32-e32, 2019 | 150 | 2019 |
Surface topography guides morphology and spatial patterning of induced pluripotent stem cell colonies G Abagnale, A Sechi, M Steger, Q Zhou, CC Kuo, G Aydin, C Schalla, ... Stem cell reports 9 (2), 654-666, 2017 | 144 | 2017 |
Impact of missing data imputation methods on gene expression clustering and classification MCP De Souto, PA Jaskowiak, IG Costa BMC bioinformatics 16, 1-9, 2015 | 136 | 2015 |
Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures M Eipel, F Mayer, T Arent, MRP Ferreira, C Birkhofer, U Gerstenmaier, ... Aging (Albany NY) 8 (5), 1034, 2016 | 127 | 2016 |