| Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression M Otsuka, Q Jing, P Georgel, L New, J Chen, J Mols, YJ Kang, Z Jiang, ... Immunity 27 (1), 123-134, 2007 | 445 | 2007 |
| Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma V Kumar, N Kato, Y Urabe, A Takahashi, R Muroyama, N Hosono, ... Nature genetics 43 (5), 455-458, 2011 | 438 | 2011 |
| Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice M Otsuka, M Zheng, M Hayashi, JD Lee, O Yoshino, S Lin, J Han The Journal of clinical investigation 118 (5), 1944-1954, 2008 | 408 | 2008 |
| Activation of intracellular signaling by hepatitis B and C viruses: C-viral core is the most potent signal inducer N Kato, H Yoshida, SK Ono-Nita, J Kato, T Goto, M Otsuka, K Lan, ... Hepatology 32 (2), 405-412, 2000 | 349 | 2000 |
| Full-length cDNA T Isogai, T Sugiyama, T Otsuki, A Wakamatsu, H Sato, S Ishii, ... US Patent 6,943,241, 2005 | 325 | 2005 |
| Serum metabolomics reveals γ-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease T Soga, M Sugimoto, M Honma, M Mori, K Igarashi, K Kashikura, S Ikeda, ... Journal of hepatology 55 (4), 896-905, 2011 | 258 | 2011 |
| Interleukin-1β gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection Y Wang, N Kato, Y Hoshida, H Yoshida, H Taniguchi, T Goto, M Moriyama, ... Hepatology 37 (1), 65-71, 2003 | 216 | 2003 |
| Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability M Otsuka, N Kato, KH Lan, H Yoshida, J Kato, T Goto, Y Shiratori, ... Journal of Biological Chemistry 275 (44), 34122-34130, 2000 | 215 | 2000 |
| Macrophage deletion of p38α partially impairs lipopolysaccharide-induced cellular activation YJ Kang, J Chen, M Otsuka, J Mols, S Ren, Y Wang, J Han The Journal of Immunology 180 (7), 5075-5082, 2008 | 188 | 2008 |
| Hepatitis C virus core protein upregulates transforming growth factor‐β1 transcription H Taniguchi, N Kato, M Otsuka, T Goto, H Yoshida, Y Shiratori, M Omata Journal of medical virology 72 (1), 52-59, 2004 | 178 | 2004 |
| Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses M Otsuka, N Kato, M Moriyama, H Taniguchi, Y Wang, N Dharel, ... Hepatology 41 (5), 1004-1012, 2005 | 173 | 2005 |
| Vitamin K2 inhibits the growth and invasiveness of hepatocellular carcinoma cells via protein kinase A activation M Otsuka, N Kato, RX Shao, Y Hoshida, H Ijichi, Y Koike, H Taniguchi, ... Hepatology 40 (1), 243-251, 2004 | 172 | 2004 |
| Hepatitis C virus core protein is a potent inhibitor of RNA silencing-based antiviral response Y Wang, N Kato, A Jazag, N Dharel, M Otsuka, H Taniguchi, T Kawabe, ... Gastroenterology 130 (3), 883-892, 2006 | 143 | 2006 |
| MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma K Kojima, A Takata, C Vadnais, M Otsuka, T Yoshikawa, M Akanuma, ... Nature communications 2 (1), 338, 2011 | 140 | 2011 |
| MicroRNA‐140 acts as a liver tumor suppressor by controlling NF‐κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression A Takata, M Otsuka, T Yoshikawa, T Kishikawa, Y Hikiba, S Obi, T Goto, ... Hepatology 57 (1), 162-170, 2013 | 133 | 2013 |
| Cell surface 4-1BBL mediates sequential signaling pathways' downstream'of TLR and is required for sustained TNF production in macrophages YJ Kang, SO Kim, S Shimada, M Otsuka, A Seit-Nebi, BS Kwon, TH Watts, ... Nature immunology 8 (6), 601-609, 2007 | 133 | 2007 |
| Hepatitis C virus core protein activates nuclear factor κB-dependent signaling through tumor necrosis factor receptor-associated factor H Yoshida, N Kato, Y Shiratori, M Otsuka, S Maeda, J Kato, M Omata Journal of Biological Chemistry 276 (19), 16399-16405, 2001 | 130 | 2001 |
| Calcineurin negatively regulates TLR-mediated activation pathways YJ Kang, B Kusler, M Otsuka, M Hughes, N Suzuki, S Suzuki, WC Yeh, ... The Journal of Immunology 179 (7), 4598-4607, 2007 | 129 | 2007 |
| Differential expression of the L-plastin gene in human colorectal cancer progression and metastasis M Otsuka, M Kato, T Yoshikawa, H Chen, EJ Brown, Y Masuho, M Omata, ... Biochemical and Biophysical Research Communications 289 (4), 876-881, 2001 | 127 | 2001 |
| Smad4-independent regulation of p21/WAF1 by transforming growth factor-β H Ijichi, M Otsuka, K Tateishi, T Ikenoue, T Kawakami, F Kanai, Y Arakawa, ... Oncogene 23 (5), 1043-1051, 2004 | 118 | 2004 |
