Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells P Roelandt, KA Pauwelyn, P Sancho-Bru, K Subramanian, B Bose, ... PloS one 5 (8), e12101, 2010 | 109 | 2010 |
Spheroid culture for enhanced differentiation of human embryonic stem cells to hepatocyte-like cells K Subramanian, DJ Owens, R Raju, M Firpo, TD O'Brien, CM Verfaillie, ... Stem cells and development 23 (2), 124-131, 2014 | 93 | 2014 |
Methods to modulate lysine variant distribution K Subramanian, M Perez, X Zeng, CF Wong, C Chumsae US Patent 9,181,572, 2015 | 58 | 2015 |
Cell culture methods to reduce acidic species K Subramanian, X Zeng, DD Dong, WC Lim, KA Gifford, C Chumsae US Patent 9,150,645, 2015 | 55 | 2015 |
Isolation procedure and characterization of multipotent adult progenitor cells from rat bone marrow K Subramanian, M Geraerts, KA Pauwelyn, Y Park, DJ Owens, ... Cellular Programming and Reprogramming: Methods and Protocols, 55-78, 2010 | 50 | 2010 |
Expansion and hepatic differentiation of rat multipotent adult progenitor cells in microcarrier suspension culture Y Park, K Subramanian, CM Verfaillie, WS Hu Journal of biotechnology 150 (1), 131-139, 2010 | 42 | 2010 |
Low acidic species compositions and methods for producing and using the same N Ramasubramanyan, L Yang, MO Herigstad, H Yang, K Subramanian, ... US Patent 9,085,618, 2015 | 39 | 2015 |
Effect of cysteine on methionine production by a regulatory mutant of Corynebacterium lilium D Kumar, K Subramanian, VS Bisaria, TR Sreekrishnan, J Gomes Bioresource technology 96 (3), 287-294, 2005 | 35 | 2005 |
MAPC culture conditions support the derivation of cells with nascent hypoblast features from bone marrow and blastocysts A Lo Nigro, M Geraerts, T Notelaers, VD Roobrouck, M Muijtjens, ... Journal of molecular cell biology 4 (6), 423-426, 2012 | 34 | 2012 |
Modulated lysine variant species compositions and methods for producing and using the same K Subramanian, MP Thiele, X Zeng, CF Wong, Z Kaymakcalan, Y Jing, ... US Patent 9,181,337, 2015 | 33 | 2015 |
Low acidic species compositions and methods for producing and using the same N Ramasubramanyan, L Yang, MO Herigstad, H Yang, K Subramanian, ... US Patent 9,266,949, 2016 | 29 | 2016 |
Cell culture methods to reduce acidic species K Subramanian, X Zeng, DD Dong, WC Lim, KA Gifford, C Chumsae US Patent 9,359,434, 2016 | 27 | 2016 |
Low acidic species compositions and methods for producing and using the same N Ramasubramanyan, L Yang, MO Herigstad, H Yang, K Subramanian, ... US Patent 9,315,574, 2016 | 26 | 2016 |
Scalable expansion of multipotent adult progenitor cells as three‐dimensional cell aggregates K Subramanian, Y Park, CM Verfaillie, WS Hu Biotechnology and bioengineering 108 (2), 364-375, 2011 | 25 | 2011 |
Low acidic species compositions and methods for producing and using the same N Ramasubramanyan, L Yang, MO Herigstad, H Yang, K Subramanian, ... US Patent 9,200,069, 2015 | 24 | 2015 |
Non-static suspension culture of cell aggregates K Subramanian, WS Hu, CM Verfaillie, Y Park US Patent 8,609,406, 2013 | 23 | 2013 |
Enhanced differentiation of adult bone marrow-derived stem cells to liver lineage in aggregate culture K Subramanian, DJ Owens, TD O'Brien, CM Verfaillie, WS Hu Tissue Engineering Part A 17 (17-18), 2331-2341, 2011 | 20 | 2011 |
Low acidic species compositions and methods for producing and using the same N Ramasubramanyan, L Yang, MO Herigstad, H Yang, K Subramanian, ... US Patent 9,200,070, 2015 | 19 | 2015 |
Cell culture methods to reduce acidic species K Subramanian, X Zeng, DD Dong, WC Lim, KA Gifford, C Chumsae US Patent 9,683,033, 2017 | 18 | 2017 |
Low acidic species compositions and methods for producing and using the same N Ramasubramanyan, L Yang, MO Herigstad, H Yang, K Subramanian, ... US Patent 9,522,953, 2016 | 16 | 2016 |