G‐quadruplex recognition by quinacridines: a SAR, NMR, and biological study C Hounsou, L Guittat, D Monchaud, M Jourdan, N Saettel, JL Mergny, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (5), 655-666, 2007 | 134 | 2007 |
DNA switches on the two-photon efficiency of an ultrabright triphenylamine fluorescent probe specific of AT regions B Dumat, G Bordeau, E Faurel-Paul, F Mahuteau-Betzer, N Saettel, ... Journal of the American Chemical Society 135 (34), 12697-12706, 2013 | 101 | 2013 |
Benchmark of four popular virtual screening programs: construction of the active/decoy dataset remains a major determinant of measured performance L Chaput, J Martinez-Sanz, N Saettel, L Mouawad Journal of cheminformatics 8, 1-17, 2016 | 98 | 2016 |
“One Ring to Bind Them All”—Part I: The Efficiency of the Macrocyclic Scaffold for G‐Quadruplex DNA Recognition D Monchaud, A Granzhan, N Saettel, A Guédin, JL Mergny, ... Journal of Nucleic Acids 2010 (1), 525862, 2010 | 81 | 2010 |
N-phenyl-carbazole-based two-photon fluorescent probes: Strong sequence dependence of the duplex vs quadruplex selectivity B Dumat, G Bordeau, E Faurel-Paul, F Mahuteau-Betzer, N Saettel, ... Biochimie 93 (8), 1209-1218, 2011 | 64 | 2011 |
Isotope effects and the mechanism of an electron-transfer-catalyzed Diels− Alder reaction NJ Saettel, O Wiest, DA Singleton, MP Meyer Journal of the American Chemical Society 124 (38), 11552-11559, 2002 | 62 | 2002 |
Macrocyclic DNA‐Mismatch‐Binding Ligands: Structural Determinants of Selectivity A Granzhan, E Largy, N Saettel, MP Teulade‐Fichou Chemistry–A European Journal 16 (3), 878-889, 2010 | 54 | 2010 |
Design, synthesis, and evaluation of a biomimetic artificial photolyase model O Wiest, CB Harrison, NJ Saettel, R Cibulka, M Sax, B König The Journal of Organic Chemistry 69 (24), 8183-8185, 2004 | 47 | 2004 |
DFT study of the [2+ 2] cycloreversion of uracil dimer anion radical: Waters matter NJ Saettel, O Wiest Journal of the American Chemical Society 123 (11), 2693-2694, 2001 | 47 | 2001 |
Recognition of G‐Quadruplex DNA by Triangular Star‐Shaped Compounds: With or Without Side Chains? H Bertrand, A Granzhan, D Monchaud, N Saettel, R Guillot, S Clifford, ... Chemistry–A European Journal 17 (16), 4529-4539, 2011 | 44 | 2011 |
“One Ring to Bind Them All”—Part II: Identification of Promising G‐Quadruplex Ligands by Screening of Cyclophane‐Type Macrocycles A Granzhan, D Monchaud, N Saettel, A Guédin, JL Mergny, ... Journal of Nucleic Acids 2010 (1), 460561, 2010 | 42 | 2010 |
Inhibitors of the TAM subfamily of tyrosine kinases: synthesis and biological evaluation RM Suarez, F Chevot, A Cavagnino, N Saettel, F Radvanyi, S Piguel, ... European journal of medicinal chemistry 61, 2-25, 2013 | 41 | 2013 |
Pericyclic reactions of radical cations NJ Saettel, J Oxgaard, O Wiest European Journal of Organic Chemistry 2001 (8), 1429-1439, 2001 | 41 | 2001 |
Ab initio studies of [1, 5]-H shifts: Pentadiene and beyond NJ Saettel, O Wiest The Journal of Organic Chemistry 65 (8), 2331-2336, 2000 | 40 | 2000 |
Triazatrinaphthylene, a three-fold symmetry planar conjugated system with two-dimensional self-assembly properties N Saettel, N Katsonis, A Marchenko, MP Teulade-Fichou, D Fichou Journal of Materials Chemistry 15 (31), 3175-3180, 2005 | 32 | 2005 |
Molecular Modeling Studies Focused on 5-HT7 versus 5-HT1A Selectivity. Discovery of Novel Phenylpyrrole Derivatives with High Affinity for 5-HT7 Receptors A Lepailleur, R Bureau, M Paillet-Loilier, F Fabis, N Saettel, S Lemaître, ... Journal of chemical information and modeling 45 (4), 1075-1081, 2005 | 31 | 2005 |
3D Pharmacophore, hierarchical methods, and 5-HT4 receptor binding data T Varin, N Saettel, J Villain, A Lesnard, F Dauphin, R Bureau, S Rault Journal of Enzyme Inhibition and Medicinal Chemistry 23 (5), 593-603, 2008 | 26 | 2008 |
New aminopyrimidine derivatives as inhibitors of the TAM family T Traoré, A Cavagnino, N Saettel, F Radvanyi, S Piguel, I Bernard-Pierrot, ... European Journal of Medicinal Chemistry 70, 789-801, 2013 | 21 | 2013 |
Screening of a chemical library by HT-G4-FID for discovery of selective G-quadruplex binders E Largy, N Saettel, F Hamon, S Dubruille, MP Teulade-Fichou Current pharmaceutical design 18 (14), 1992-2001, 2012 | 21 | 2012 |
Palladium versus copper-catalyzed N-arylation towards an efficient access to polysubstituted dibenzophenanthrolines and carbazoles C Jacquelin, N Saettel, C Hounsou, MP Teulade-Fichou Tetrahedron letters 46 (15), 2589-2592, 2005 | 20 | 2005 |