Savignygrin, a platelet aggregation inhibitor from the soft tickOrnithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold BJ Mans, AI Louw, AWH Neitz Journal of Biological Chemistry 277 (24), 21371-21378, 2002 | 156 | 2002 |
Evolution of hematophagy in ticks: common origins for blood coagulation and platelet aggregation inhibitors from soft ticks of the genus Ornithodoros BJ Mans, AI Louw, AWH Neitz Molecular Biology and Evolution 19 (10), 1695-1705, 2002 | 148 | 2002 |
Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities LM Birkholtz, M Williams, J Niemand, AI Louw, L Persson, O Heby Biochemical Journal 438 (2), 229-244, 2011 | 114 | 2011 |
Heterologous expression of plasmodial proteins for structural studies and functional annotation LM Birkholtz, G Blatch, TL Coetzer, HC Hoppe, E Human, EJ Morris, ... Malaria journal 7, 1-20, 2008 | 111 | 2008 |
Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome … AC van Brummelen, KL Olszewski, D Wilinski, M Llinas, AI Louw, ... Journal of Biological Chemistry 284 (7), 4635-4646, 2009 | 107 | 2009 |
In vitro antiplasmodial activity and cytotoxicity of ethnobotanically selected South African plants EA Prozesky, JJM Meyer, AI Louw Journal of Ethnopharmacology 76 (3), 239-245, 2001 | 98 | 2001 |
The synergism of cardiotoxin and phospholipase A2 in hemolysis AI Louw, L Visser Biochimica et Biophysica Acta (BBA)-Biomembranes 512 (1), 163-171, 1978 | 93 | 1978 |
The major tick salivary gland proteins and toxins from the soft tick, Ornithodoros savignyi, are part of the tick Lipocalin family: implications for the origins of tick toxicoses BJ Mans, AI Louw, AWH Neitz Molecular Biology and Evolution 20 (7), 1158-1167, 2003 | 84 | 2003 |
Cloning, nucleotide sequence and expression of the gene encoding factor Xa inhibitor from the salivary glands of the tick, Ornithodoros savignyi AM Joubert, AI Louw, F Joubert, AWH Neitz Experimental & applied acarology 22, 603-619, 1998 | 82 | 1998 |
Apyrase Activity and Platelet Aggregation Inhibitors in the Tick Ornithodoros Savignyi (Acari: Argasidae) BJ Mans, A Gaspar, AI Louw, AWH Neitz Experimental & applied acarology 22, 353-366, 1998 | 82 | 1998 |
Amino acid sequence and structure modeling of savignin, a thrombin inhibitor from the tick, Ornithodoros savignyi BJ Mans, AI Louw, AWH Neitz Insect Biochemistry and Molecular Biology 32 (7), 821-828, 2002 | 72 | 2002 |
Pathogenic mechanisms of sand tampan toxicoses induced by the tick, Ornithodoros savignyi BJ Mans, CML Steinmann, JD Venter, AI Louw, AWH Neitz Toxicon 40 (7), 1007-1016, 2002 | 70 | 2002 |
Moniliformin, a mycotoxin from Fusarium fusarioides CJ Rabie, A Lubben, AI Louw, EB Rathbone, PS Steyn, R Vleggaar Journal of Agricultural and Food Chemistry 26 (2), 375-379, 1978 | 69 | 1978 |
Kinetics of erythrocyte lysis by snake venom cardiotoxins AI Louw, L Visser Biochimica et Biophysica Acta (BBA)-General Subjects 498 (1), 143-153, 1977 | 63 | 1977 |
Parasite-specific inserts in the bifunctional S-adenosylmethionine decarboxylase/ornithine decarboxylase of Plasmodium falciparum modulate catalytic activities and domain … LM Birkholtz, C Wrenger, F Joubert, GA Wells, RD Walter, AI Louw Biochemical Journal 377 (2), 439-448, 2004 | 56 | 2004 |
Improved synthesis of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) AI Louw, I Bekersky, EH Mosbach Journal of Lipid Research 10 (6), 683-686, 1969 | 56 | 1969 |
Identification of putative proteins involved in granule biogenesis of tick salivary glands BJ Mans, JD Venter, PJ Vrey, AI Louw, AWH Neitz Electrophoresis 22 (9), 1739-1746, 2001 | 52 | 2001 |
Disaggregation of aggregated platelets by apyrase from the tick, Ornithodoros savignyi BJ Mans, J Coetzee, AI Louw, ARM Gaspar, AWH Neitz Experimental & applied acarology 24, 271-282, 2000 | 51 | 2000 |
Purification and characterization of apyrase from the tick, Ornithodoros savignyi BJ Mans, A Gaspar, AI Louw, AWH Neitz Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 1998 | 51 | 1998 |
Snake venom toxins The purification and properties of five non-neurotoxic polypeptides from Naja mossambica mossambica venom AI Louw Biochimica et Biophysica Acta (BBA)-Protein Structure 336 (2), 470-480, 1974 | 50 | 1974 |