A clustering approach to multireference alignment of single-particle projections in electron microscopy COS Sorzano, JR Bilbao-Castro, Y Shkolnisky, M Alcorlo, R Melero, ... Journal of structural biology 171 (2), 197-206, 2010 | 229 | 2010 |
MonoRes: automatic and accurate estimation of local resolution for electron microscopy maps JL Vilas, J Gómez-Blanco, P Conesa, R Melero, JM de la Rosa-Trevín, ... Structure 26 (2), 337-344. e4, 2018 | 228 | 2018 |
Quaternary structures of tumor suppressor p53 and a specific p53–DNA complex H Tidow, R Melero, E Mylonas, SMV Freund, JG Grossmann, JM Carazo, ... Proceedings of the National Academy of Sciences 104 (30), 12324-12329, 2007 | 227 | 2007 |
Role of group VIA calcium-independent phospholipase A2 in arachidonic acid release, phospholipid fatty acid incorporation, and apoptosis in U937 cells responding to hydrogen … R Pérez, R Melero, MA Balboa, J Balsinde Journal of Biological Chemistry 279 (39), 40385-40391, 2004 | 219 | 2004 |
Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo A Ljubetič, F Lapenta, H Gradišar, I Drobnak, J Aupič, Ž Strmšek, ... Nature biotechnology 35 (11), 1094-1101, 2017 | 186 | 2017 |
Averaging of electron subtomograms and random conical tilt reconstructions through likelihood optimization SHW Scheres, R Melero, M Valle, JM Carazo Structure 17 (12), 1563-1572, 2009 | 134 | 2009 |
Automatic local resolution-based sharpening of cryo-EM maps E Ramírez-Aportela, JL Vilas, A Glukhova, R Melero, P Conesa, ... Bioinformatics 36 (3), 765-772, 2020 | 128 | 2020 |
Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis C Sacristan, MUD Ahmad, J Keller, J Fermie, V Groenewold, E Tromer, ... Nature cell biology 20 (7), 800-810, 2018 | 119 | 2018 |
Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD R Melero, A Uchiyama, R Castaño, N Kataoka, H Kurosawa, S Ohno, ... Structure 22 (8), 1105-1119, 2014 | 99 | 2014 |
The cryo-EM structure of the UPF–EJC complex shows UPF1 poised toward the RNA 3′ end R Melero, G Buchwald, R Castaño, M Raabe, D Gil, M Lázaro, H Urlaub, ... Nature structural & molecular biology 19 (5), 498-505, 2012 | 87 | 2012 |
Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA R Melero, S Rajagopalan, M Lázaro, AC Joerger, T Brandt, DB Veprintsev, ... Proceedings of the National Academy of Sciences 108 (2), 557-562, 2011 | 86 | 2011 |
Flexible tethering of primase and DNA Pol α in the eukaryotic primosome R Núñez-Ramírez, S Klinge, L Sauguet, R Melero, MA Recuero-Checa, ... Nucleic acids research 39 (18), 8187-8199, 2011 | 78 | 2011 |
Survey of the analysis of continuous conformational variability of biological macromolecules by electron microscopy COS Sorzano, A Jiménez, J Mota, JL Vilas, D Maluenda, M Martínez, ... Acta Crystallographica Section F: Structural Biology Communications 75 (1 …, 2019 | 62 | 2019 |
Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex A Lopez-Perrote, R Castano, R Melero, T Zamarro, H Kurosawa, ... Nucleic acids research 44 (4), 1909-1923, 2016 | 59 | 2016 |
The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation R Melero, N Hug, A López-Perrote, A Yamashita, JF Cáceres, O Llorca Nature communications 7 (1), 10585, 2016 | 50 | 2016 |
Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells SD Carter, CM Hampton, R Langlois, R Melero, ZJ Farino, MJ Calderon, ... Science advances 6 (14), eaay9572, 2020 | 48 | 2020 |
Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures R Melero, COS Sorzano, B Foster, JL Vilas, M Martínez, R Marabini, ... IUCrJ 7 (6), 1059-1069, 2020 | 45 | 2020 |
A survey of the use of iterative reconstruction algorithms in electron microscopy COS Sorzano, J Vargas, J Otón, JM De La Rosa-Trevín, JL Vilas, ... BioMed research international 2017 (1), 6482567, 2017 | 40 | 2017 |
Self-assembly and regulation of protein cages from pre-organised coiled-coil modules F Lapenta, J Aupič, M Vezzoli, Ž Strmšek, S Da Vela, DI Svergun, ... Nature communications 12 (1), 939, 2021 | 39 | 2021 |
Molecular architecture and structural transitions of a Clostridium thermocellum mini-cellulosome B García-Alvarez, R Melero, FMV Dias, JAM Prates, CMGA Fontes, ... Journal of molecular biology 407 (4), 571-580, 2011 | 39 | 2011 |