Analytical validation of quantitative real-time PCR methods for quantification of Trypanosoma cruzi DNA in blood samples from Chagas disease patients JC Ramírez, CI Cura, O da Cruz Moreira, E Lages-Silva, N Juiz, ... The Journal of Molecular Diagnostics 17 (5), 605-615, 2015 | 226 | 2015 |
Towards the establishment of a consensus real-time qPCR to monitor Trypanosoma cruzi parasitemia in patients with chronic Chagas disease cardiomyopathy: a substudy from the … OC Moreira, JD Ramírez, E Velázquez, MFAD Melo, C Lima-Ferreira, ... Acta Tropica 125 (1), 23-31, 2013 | 172 | 2013 |
Unraveling Chagas disease transmission through the oral route: Gateways to Trypanosoma cruzi infection and target tissues D Silva-dos-Santos, J Barreto-de-Albuquerque, B Guerra, OC Moreira, ... PLoS neglected tropical diseases 11 (4), e0005507, 2017 | 100 | 2017 |
A Human Type 5 Adenovirus-Based Trypanosoma cruzi Therapeutic Vaccine Re-programs Immune Response and Reverses Chronic Cardiomyopathy IR Pereira, G Vilar-Pereira, V Marques, AA da Silva, B Caetano, ... PLoS pathogens 11 (1), e1004594, 2015 | 92 | 2015 |
Trypanosoma cruzi Infection through the Oral Route Promotes a Severe Infection in Mice: New Disease Form from an Old Infection? J Barreto-de-Albuquerque, D Silva-dos-Santos, AR Pérez, LR Berbert, ... PLoS neglected tropical diseases 9 (6), e0003849, 2015 | 91 | 2015 |
SYBR Green-based real-time PCR targeting kinetoplast DNA can be used to discriminate between the main etiologic agents of Brazilian cutaneous and visceral leishmaniases D Pita-Pereira, R Lins, MP Oliveira, RB Lima, BAS Pereira, OC Moreira, ... Parasites & vectors 5, 1-9, 2012 | 73 | 2012 |
TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas’ heart disease RR Ferreira, R da Silva Abreu, G Vilar-Pereira, W Degrave, ... PLoS neglected tropical diseases 13 (7), e0007602, 2019 | 69 | 2019 |
Impact of Trypanosoma cruzi on antimicrobial peptide gene expression and activity in the fat body and midgut of Rhodnius prolixus CS Vieira, PJ Waniek, DP Castro, DP Mattos, OC Moreira, P Azambuja Parasites & vectors 9, 1-12, 2016 | 67 | 2016 |
Usefulness of real time PCR to quantify parasite load in serum samples from chronic Chagas disease patients MF Melo, OC Moreira, P Tenório, V Lorena, I Lorena-Rezende, WO Júnior, ... Parasites & vectors 8, 1-7, 2015 | 67 | 2015 |
Tumor necrosis factor is a therapeutic target for immunological unbalance and cardiac abnormalities in chronic experimental Chagas’ heart disease IR Pereira, G Vilar-Pereira, AA Silva, OC Moreira, C Britto, EDM Sarmento, ... Mediators of inflammation 2014 (1), 798078, 2014 | 66 | 2014 |
A prophylactic α-Gal-based glycovaccine effectively protects against murine acute Chagas disease S Portillo, BG Zepeda, E Iniguez, JJ Olivas, NH Karimi, OC Moreira, ... npj Vaccines 4 (1), 13, 2019 | 63 | 2019 |
Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions G Vilar-Pereira, AA da Silva, IR Pereira, RR Silva, OC Moreira, ... Brain, behavior, and immunity 26 (7), 1136-1149, 2012 | 57 | 2012 |
Exploring the parasite load and molecular diversity of Trypanosoma cruzi in patients with chronic Chagas disease from different regions of Brazil I Rodrigues-dos-Santos, MF Melo, L de Castro, AM Hasslocher-Moreno, ... PLoS neglected tropical diseases 12 (11), e0006939, 2018 | 56 | 2018 |
Inducible Nitric Oxide Synthase in Heart Tissue and Nitric Oxide in Serum of Trypanosoma cruzi-Infected Rhesus Monkeys: Association with Heart Injury CME Carvalho, JC Silverio, AA Da Silva, IR Pereira, JMC Coelho, ... PLoS neglected tropical diseases 6 (5), e1644, 2012 | 54 | 2012 |
The applicability of real-time PCR in the diagnostic of cutaneous leishmaniasis and parasite quantification for clinical management: current status and perspectives OC Moreira, ZE Yadon, E Cupolillo Acta tropica 184, 29-37, 2018 | 53 | 2018 |
An α-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major E Iniguez, NS Schocker, K Subramaniam, S Portillo, AL Montoya, ... PLoS Neglected Tropical Diseases 11 (10), e0006039, 2017 | 51 | 2017 |
Cruzipain Promotes Trypanosoma cruzi Adhesion to Rhodnius prolixus Midgut LA Uehara, OC Moreira, AC Oliveira, P Azambuja, APCA Lima, C Britto, ... PLoS neglected tropical diseases 6 (12), e1958, 2012 | 50 | 2012 |
Effects of γ-irradiation on the membrane ATPases of human erythrocytes from transfusional blood concentrates OC Moreira, VH Oliveira, LBF Benedicto, CM Nogueira, JA Mignaco, ... Annals of Hematology 87, 113-119, 2008 | 50 | 2008 |
Comparative evaluation of lesion development, tissue damage, and cytokine expression in golden hamsters (Mesocricetus auratus) infected by inocula with different Leishmania … RP Ribeiro-Romão, OC Moreira, EY Osorio, L Cysne-Finkelstein, ... Infection and immunity 82 (12), 5203-5213, 2014 | 48 | 2014 |
New approaches for the standardization and validation of a real-time qPCR assay using TaqMan probes for quantification of yellow fever virus on clinical samples with high … AG Fernandes-Monteiro, GF Trindade, AMY Yamamura, OC Moreira, ... Human vaccines & immunotherapeutics 11 (7), 1865-1871, 2015 | 47 | 2015 |