hnRNP K is a haploinsufficient tumor suppressor that regulates proliferation and differentiation programs in hematologic malignancies M Gallardo, HJ Lee, X Zhang, C Bueso-Ramos, LR Pageon, M McArthur, ... Cancer cell 28 (4), 486-499, 2015 | 146 | 2015 |
Aberrant hnRNP K expression: all roads lead to cancer M Gallardo, MJ Hornbaker, X Zhang, P Hu, C Bueso-Ramos, SM Post Cell Cycle 15 (12), 1552-1557, 2016 | 102 | 2016 |
High resolution melting analysis for JAK2 Exon 14 and Exon 12 mutations: a diagnostic tool for myeloproliferative neoplasms I Rapado, S Grande, E Albizua, R Ayala, JA Hernández, M Gallardo, ... The Journal of Molecular Diagnostics 11 (2), 155-161, 2009 | 73 | 2009 |
GMP-compliant manufacturing of NKG2D CAR memory T cells using CliniMACS prodigy L Fernández, A Fernández, I Mirones, A Escudero, L Cardoso, M Vela, ... Frontiers in Immunology 10, 2361, 2019 | 60 | 2019 |
Validity test study of JAK2 V617F and allele burden quantification in the diagnosis of myeloproliferative diseases I Rapado, E Albizua, R Ayala, JA Hernández, L Garcia-Alonso, S Grande, ... Annals of hematology 87, 741-749, 2008 | 57 | 2008 |
Novel deep targeted sequencing method for minimal residual disease monitoring in acute myeloid leukemia E Onecha, M Linares, I Rapado, Y Ruiz-Heredia, P Martinez-Sanchez, ... Haematologica, haematol. 2018.194712, 2018 | 44 | 2018 |
A potent isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor improves survival in Ras-driven acute myeloid leukemia NI Marín-Ramos, M Balabasquer, FJ Ortega-Nogales, IR Torrecillas, ... Journal of Medicinal Chemistry 62 (13), 6035-6046, 2019 | 38 | 2019 |
Inhibition of related JAK/STAT pathways with molecular targeted drugs shows strong synergy with ruxolitinib in chronic myeloproliferative neoplasm S Barrio, M Gallardo, A Arenas, R Ayala, I Rapado, D Rueda, ... British journal of haematology 161 (5), 667-676, 2013 | 34 | 2013 |
MEK inhibition enhances the response to tyrosine kinase inhibitors in acute myeloid leukemia ML Morales, A Arenas, A Ortiz-Ruiz, A Leivas, I Rapado, ... Scientific reports 9 (1), 18630, 2019 | 32 | 2019 |
Epigenomic profiling in polycythaemia vera and essential thrombocythaemia shows low levels of aberrant DNA methylation S Barrio, M Gallardo, E Albizua, A Jimenez, I Rapado, R Ayala, F Gilsanz, ... Journal of clinical pathology 64 (11), 1010-1013, 2011 | 32 | 2011 |
DNA-loaded extracellular vesicles in liquid biopsy: tiny players with big potential? S García-Silva, M Gallardo, H Peinado Frontiers in Cell and Developmental Biology 8, 622579, 2021 | 29 | 2021 |
Uncovering the role of RNA-binding protein hnRNP K in B-cell lymphomas M Gallardo, P Malaney, MJL Aitken, X Zhang, TM Link, V Shah, ... JNCI: Journal of the National Cancer Institute 112 (1), 95-106, 2020 | 27 | 2020 |
Monitoring of clonal evolution of acute myeloid leukemia identifies the leukemia subtype, clinical outcome and potential new drug targets for post-remission strategies or relapse E Onecha, I Rapado, ML Morales, G Carreño-Tarragona, ... Haematologica 106 (9), 2325, 2021 | 25 | 2021 |
Proteomic analysis reveals heat shock protein 70 has a key role in polycythemia Vera M Gallardo, S Barrio, M Fernandez, A Paradela, A Arenas, O Toldos, ... Molecular Cancer 12, 1-12, 2013 | 24 | 2013 |
Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse … PP Ruvolo, H Ma, VR Ruvolo, X Zhang, H Mu, W Schober, I Hernandez, ... haematologica 102 (12), 2048, 2017 | 20 | 2017 |
p53-independent ibrutinib responses in an Eμ-TCL1 mouse model demonstrates efficacy in high-risk CLL HJ Lee, M Gallardo, H Ma, X Zhang, CA Larsson, A Mejia, MJ Hornbaker, ... Blood cancer journal 6 (6), e434-e434, 2016 | 16 | 2016 |
Real-life disease monitoring in follicular lymphoma patients using liquid biopsy ultra-deep sequencing and PET/CT A Jiménez-Ubieto, M Poza, A Martin-Muñoz, Y Ruiz-Heredia, S Dorado, ... Leukemia 37 (3), 659-669, 2023 | 15 | 2023 |
Myc-related mitochondrial activity as a novel target for multiple myeloma A Ortiz-Ruiz, Y Ruiz-Heredia, ML Morales, P Aguilar-Garrido, ... Cancers 13 (7), 1662, 2021 | 13 | 2021 |
The role of RNA-binding proteins in hematological malignancies P Aguilar-Garrido, A Otero-Sobrino, MÁ Navarro-Aguadero, ... International Journal of Molecular Sciences 23 (17), 9552, 2022 | 12 | 2022 |
Mechanosensitive ion channels: their physiological importance and potential key role in cancer Á Otero-Sobrino, P Blanco-Carlón, MÁ Navarro-Aguadero, M Gallardo, ... International Journal of Molecular Sciences 24 (18), 13710, 2023 | 11 | 2023 |