Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells M Kool, T Soullié, M van Nimwegen, MAM Willart, F Muskens, S Jung, ... Journal of Experimental Medicine 205 (4), 869-882, 2008 | 1216 | 2008 |
Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome M Kool, V Pétrilli, T De Smedt, A Rolaz, H Hammad, M Van Nimwegen, ... The Journal of Immunology 181 (6), 3755-3759, 2008 | 769 | 2008 |
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells M Idzko, H Hammad, M Van Nimwegen, M Kool, MAM Willart, F Muskens, ... Nature medicine 13 (8), 913-919, 2007 | 712 | 2007 |
Inflammatory dendritic cells—not basophils—are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen H Hammad, M Plantinga, K Deswarte, P Pouliot, MAM Willart, M Kool, ... Journal of Experimental Medicine 207 (10), 2097-2111, 2010 | 694 | 2010 |
Clearance of influenza virus from the lung depends on migratory langerin+ CD11b− but not plasmacytoid dendritic cells CH GeurtsvanKessel, MAM Willart, LS van Rijt, F Muskens, M Kool, ... Journal of Experimental Medicine 205 (7), 1621-1634, 2008 | 587 | 2008 |
Mechanism of action of clinically approved adjuvants BN Lambrecht, M Kool, MAM Willart, H Hammad Current opinion in immunology 21 (1), 23-29, 2009 | 482 | 2009 |
An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma M Kool, MAM Willart, M van Nimwegen, I Bergen, P Pouliot, JC Virchow, ... Immunity 34 (4), 527-540, 2011 | 419 | 2011 |
Inflammation and Immunity in IPF Pathogenesis and Treatment P Heukels, CC Moor, JH von der Thüsen, MS Wijsenbeek, M Kool Respiratory Medicine, 2019 | 373 | 2019 |
Alum adjuvant: some of the tricks of the oldest adjuvant M Kool, K Fierens, BN Lambrecht Journal of medical microbiology 61 (7), 927-934, 2012 | 361 | 2012 |
Perinatal activation of the interleukin-33 pathway promotes type 2 immunity in the developing lung IM de Kleer, M Kool, MJW de Bruijn, M Willart, J Van Moorleghem, ... Immunity 45 (6), 1285-1298, 2016 | 324 | 2016 |
Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function M Idzko, H Hammad, M van Nimwegen, M Kool, T Müller, T Soullié, ... The Journal of clinical investigation 116 (11), 2935-2944, 2006 | 324 | 2006 |
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis M Matmati, P Jacques, J Maelfait, E Verheugen, M Kool, M Sze, L Geboes, ... Nature genetics 43 (9), 908-912, 2011 | 314 | 2011 |
Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and … CL Hofstra, I Van Ark, G Hofman, M Kool, FP Nijkamp, ... The Journal of Immunology 161 (9), 5054-5060, 1998 | 306 | 1998 |
The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity M Kool, G van Loo, W Waelput, S De Prijck, F Muskens, M Sze, ... Immunity 35 (1), 82-96, 2011 | 257 | 2011 |
IFN-γ–producing T-helper 17.1 cells are increased in sarcoidosis and are more prevalent than T-helper type 1 cells J Ramstein, CE Broos, LJ Simpson, KM Ansel, SA Sun, ME Ho, ... American journal of respiratory and critical care medicine 193 (11), 1281-1291, 2016 | 250 | 2016 |
Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses FA Redegeld, MW van der Heijden, M Kool, BM Heijdra, J Garssen, ... Nature medicine 8 (7), 694-701, 2002 | 243 | 2002 |
Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells H Hammad, M Kool, T Soullié, S Narumiya, F Trottein, HC Hoogsteden, ... Journal of Experimental Medicine 204 (2), 357-367, 2007 | 217 | 2007 |
An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation M Kool, M van Nimwegen, MAM Willart, F Muskens, L Boon, JJ Smit, ... the Journal of Immunology 183 (2), 1074-1082, 2009 | 213 | 2009 |
Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection HH Smits, H Hammad, M van Nimwegen, T Soullie, MA Willart, E Lievers, ... Journal of Allergy and Clinical Immunology 120 (4), 932-940, 2007 | 209 | 2007 |
Dendritic cell subsets and immune regulation in the lung HJ de Heer, H Hammad, M Kool, BN Lambrecht Seminars in immunology 17 (4), 295-303, 2005 | 179 | 2005 |