PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization MD Houslay, DR Adams Biochemical Journal 370 (1), 1-18, 2003 | 958 | 2003 |
RACK1, A multifaceted scaffolding protein: Structure and function DR Adams, D Ron, PA Kiely Cell Communication and Signaling 9 (1), 22, 2011 | 509 | 2011 |
The development of a marine natural product-based antifouling paint JG Burgess, KG Boyd, E Armstrong, Z Jiang, L Yan, M Berggren, U May, ... Biofouling 19 (S1), 197-205, 2003 | 318 | 2003 |
Sphingosine 1-phosphate and sphingosine kinases in health and disease: recent advances S Pyne, DR Adams, NJ Pyne Progress in Lipid Research 62, 93-106, 2016 | 196 | 2016 |
Novel anti-infective compounds from marine bacteria H Rahman, B Austin, WJ Mitchell, PC Morris, DJ Jamieson, DR Adams, ... Marine drugs 8 (3), 498-518, 2010 | 184 | 2010 |
Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, β-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5 GB Bolger, GS Baillie, X Li, MJ Lynch, P Herzyk, A Mohamed, ... Biochemical Journal 398 (1), 23-36, 2006 | 181 | 2006 |
Biofilm-specific cross-species induction of antimicrobial compounds in bacilli L Yan, KG Boyd, DR Adams, JG Burgess Applied and Environmental Microbiology 69 (7), 3719-3727, 2003 | 134 | 2003 |
Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase PA Kiely, GS Baillie, R Barrett, DA Buckley, DR Adams, MD Houslay, ... Journal of Biological Chemistry 284 (30), 20263-20274, 2009 | 125 | 2009 |
Antibacterial and repellent activities of marine bacteria associated with algal surfaces KG Boyd, DR Adams, JG Burgess Biofouling 14 (3), 227-236, 1999 | 116 | 1999 |
Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)–HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes YY Sin, HV Edwards, X Li, JP Day, F Christian, AJ Dunlop, DR Adams, ... Journal of Molecular and Cellular Cardiology 50 (5), 872-883, 2011 | 112 | 2011 |
Sphingosine 1-phosphate and cancer NJ Pyne, A El Buri, DR Adams, S Pyne Advances in Biological Regulation 68, 97-106, 2018 | 109 | 2018 |
Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N-and C-domains of β-arrestin using spot-immobilized peptide arrays GS Baillie, DR Adams, N Bhari, TM Houslay, S Vadrevu, D Meng, X Li, ... Biochemical Journal 404 (1), 71-80, 2007 | 101 | 2007 |
Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs BD Hudson, E Christiansen, IG Tikhonova, M Grundmann, E Kostenis, ... The FASEB Journal 26 (12), 4951-4965, 2012 | 81 | 2012 |
Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator NJ Smith, RJ Ward, LA Stoddart, BD Hudson, E Kostenis, T Ulven, ... Molecular Pharmacology 80 (1), 163-173, 2011 | 81 | 2011 |
MEK1 binds directly to βarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization D Meng, MJ Lynch, E Huston, M Beyermann, J Eichhorst, DR Adams, ... Journal of Biological Chemistry 284 (17), 11425-11435, 2009 | 81 | 2009 |
Sphingosine kinases: emerging structure–function insights DR Adams, S Pyne, NJ Pyne Trends in Biochemical Sciences 41 (5), 395-409, 2016 | 77 | 2016 |
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases F Omar, JE Findlay, G Carfray, RW Allcock, Z Jiang, C Moore, AL Muir, ... Proceedings of the National Academy of Sciences 116 (27), 13320-13329, 2019 | 67 | 2019 |
Two Diketopiperazines and One Halogenated Phenol from Cultures of the Marine Bacterium, Pseudoalteromonas luteoviolacea Z Jiang, KG Boyd, A Mearns-Spragg, DR Adams, PC Wright, JG Burgess Natural Product Letters 14 (6), 435-440, 2000 | 63 | 2000 |
1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the … KJ Smith, GS Baillie, EI Hyde, X Li, TM Houslay, A McCahill, AJ Dunlop, ... Cellular Signalling 19 (12), 2612-2624, 2007 | 57 | 2007 |
JM47, a cyclic tetrapeptide HC-toxin analogue from a marine Fusarium species Z Jiang, MO Barret, KG Boyd, DR Adams, ASF Boyd, JG Burgess Phytochemistry 60 (1), 33-38, 2002 | 57 | 2002 |