Common variants near MC4R are associated with fat mass, weight and risk of obesity RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ... Nature genetics 40 (6), 768-775, 2008 | 1614 | 2008 |
Polyploidy can drive rapid adaptation in yeast AM Selmecki, YE Maruvka, PA Richmond, M Guillet, N Shoresh, ... Nature 519 (7543), 349-352, 2015 | 469 | 2015 |
Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma T Vagner, C Spinelli, VR Minciacchi, L Balaj, M Zandian, A Conley, ... Journal of extracellular vesicles 7 (1), 1505403, 2018 | 342 | 2018 |
A HaemAtlas: characterizing gene expression in differentiated human blood cells NA Watkins, A Gusnanto, B De Bono, S De, D Miranda-Saavedra, ... Blood, The Journal of the American Society of Hematology 113 (19), e1-e9, 2009 | 292 | 2009 |
DNA secondary structures and epigenetic determinants of cancer genome evolution S De, F Michor Nature structural & molecular biology 18 (8), 950-955, 2011 | 261 | 2011 |
Evolution of the cancer genome O Podlaha, M Riester, S De, F Michor Trends in Genetics 28 (4), 155-163, 2012 | 207 | 2012 |
Dopamine mediates context-dependent modulation of sensory plasticity in C. elegans KS Kindt, KB Quast, AC Giles, S De, D Hendrey, I Nicastro, CH Rankin, ... Neuron 55 (4), 662-676, 2007 | 204 | 2007 |
DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells YJ He, K Meghani, MC Caron, C Yang, DA Ronato, J Bian, A Sharma, ... Nature 563 (7732), 522-526, 2018 | 197 | 2018 |
DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes S De, F Michor Nature biotechnology 29 (12), 1103-1108, 2011 | 186 | 2011 |
Somatic mosaicism in healthy human tissues S De Trends in Genetics 27 (6), 217-223, 2011 | 180 | 2011 |
Cellular crowding imposes global constraints on the chemistry and evolution of proteomes ED Levy, S De, SA Teichmann Proceedings of the National Academy of Sciences 109 (50), 20461-20466, 2012 | 177 | 2012 |
Evolutionary pathways in BRCA1-associated breast tumors FC Martins, S De, V Almendro, M Gönen, SY Park, JL Blum, W Herlihy, ... Cancer discovery 2 (6), 503-511, 2012 | 164 | 2012 |
Weakly supervised deep nuclei segmentation using partial points annotation in histopathology images H Qu, P Wu, Q Huang, J Yi, Z Yan, K Li, GM Riedlinger, S De, S Zhang, ... IEEE transactions on medical imaging 39 (11), 3655-3666, 2020 | 152 | 2020 |
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation R Shaknovich, L Cerchietti, L Tsikitas, M Kormaksson, S De, ME Figueroa, ... Blood, The Journal of the American Society of Hematology 118 (13), 3559-3569, 2011 | 152 | 2011 |
Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity S De, R Shaknovich, M Riester, O Elemento, H Geng, M Kormaksson, ... PLoS genetics 9 (1), e1003137, 2013 | 134 | 2013 |
DNA replication timing and higher-order nuclear organization determine single-nucleotide substitution patterns in cancer genomes L Liu, S De, F Michor Nature communications 4 (1), 1502, 2013 | 130 | 2013 |
Interaction preferences across protein-protein interfaces of obligatory and non-obligatory components are different S De, O Krishnadev, N Srinivasan, N Rekha BMC structural biology 5, 1-16, 2005 | 123 | 2005 |
Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes N Chambwe, M Kormaksson, H Geng, S De, F Michor, NA Johnson, ... Blood, The Journal of the American Society of Hematology 123 (11), 1699-1708, 2014 | 114 | 2014 |
Expression profiling of macrophages reveals multiple populations with distinct biological roles in an immunocompetent orthotopic model of lung cancer JM Poczobutt, S De, VK Yadav, TT Nguyen, H Li, TR Sippel, ... The Journal of Immunology 196 (6), 2847-2859, 2016 | 110 | 2016 |
Non-genetic intra-tumor heterogeneity is a major predictor of phenotypic heterogeneity and ongoing evolutionary dynamics in lung tumors A Sharma, E Merritt, X Hu, A Cruz, C Jiang, H Sarkodie, Z Zhou, ... Cell reports 29 (8), 2164-2174. e5, 2019 | 106 | 2019 |