| Use of surface plasmon resonance (SPR) to determine binding affinities and kinetic parameters between components important in fusion machinery RP Sparks, JL Jenkins, R Fratti SNAREs: Methods and Protocols, 199-210, 2019 | 53 | 2019 |
| Use of microscale thermophoresis (MST) to measure binding affinities of components of the fusion machinery RP Sparks, R Fratti SNAREs: Methods and Protocols, 191-198, 2019 | 39 | 2019 |
| Phosphatidic acid induces conformational changes in Sec18 protomers that prevent SNARE priming ML Starr, RP Sparks, AS Arango, LR Hurst, Z Zhao, M Lihan, JL Jenkins, ... Journal of Biological Chemistry 294 (9), 3100-3116, 2019 | 29 | 2019 |
| The central polybasic region of the soluble SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) Vam7 affects binding to phosphatidylinositol 3 … GE Miner, ML Starr, LR Hurst, RP Sparks, M Padolina, RA Fratti Journal of Biological Chemistry 291 (34), 17651-17663, 2016 | 29 | 2016 |
| The enigmatic role of sortilin in lipoprotein metabolism CE Sparks, RP Sparks, JD Sparks Current opinion in lipidology 26 (6), 598-600, 2015 | 19 | 2015 |
| Small molecule targeting long noncoding RNA GAS5 administered intranasally improves neuronal insulin signaling and decreases neuroinflammation in an aged mouse model RS Patel, A Lui, C Hudson, L Moss, RP Sparks, SE Hill, Y Shi, J Cai, ... Scientific reports 13 (1), 317, 2023 | 17 | 2023 |
| Phosphatidylinositol (3, 4, 5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding RP Sparks, JL Jenkins, GE Miner, Y Wang, WC Guida, CE Sparks, ... Biochemical and biophysical research communications 479 (3), 551-556, 2016 | 17 | 2016 |
| Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells RP Sparks, WC Guida, MP Sowden, JL Jenkins, ML Starr, RA Fratti, ... Biochemical and biophysical research communications 478 (2), 546-552, 2016 | 17 | 2016 |
| Use of microscale thermophoresis to measure protein-lipid interactions RP Sparks, W Lawless, AS Arango, E Tajkhorshid, RA Fratti Journal of Visualized Experiments, 2022 | 14 | 2022 |
| Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells W Li, JY Chen, C Sun, RP Sparks, L Pantano, RU Rahman, SP Moran, ... Elife 11, e74513, 2022 | 11 | 2022 |
| An allosteric binding site on sortilin regulates the trafficking of VLDL, PCSK9, and LDLR in hepatocytes RP Sparks, AS Arango, JL Jenkins, WC Guida, E Tajkhorshid, CE Sparks, ... Biochemistry 59 (45), 4321-4335, 2020 | 10 | 2020 |
| A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion RP Sparks, AS Arango, ML Starr, ZL Aboff, LR Hurst, DA Rivera-Kohr, ... Journal of Biological Chemistry 294 (46), 17168-17185, 2019 | 10 | 2019 |
| A specific small-molecule inhibitor of protein kinase CδI activity improves metabolic dysfunction in human adipocytes from obese individuals R Sparks, A Lui, D Bader, R Patel, M Murr, W Guida, R Fratti, NA Patel Journal of Biological Chemistry 294 (41), 14896-14910, 2019 | 6 | 2019 |
| Sortilin-binding small molecules for increasing glucose uptake NA Patel, RP Sparks, WC Guida US Patent 10,849,896, 2020 | 4 | 2020 |
| Sortilin binding compounds, formulations, and uses thereof RP Sparks, WC Guida, JL DeHoff-Sparks US Patent 10,478,421, 2019 | 4 | 2019 |
| Singletrome: a method to analyze and enhance the transcriptome with long noncoding RNAs for single cell analysis RU Rahman, I Ahmad, R Sparks, AB Saad, A Mullen bioRxiv, 2022.10. 31.514182, 2022 | 3 | 2022 |
| Cupriphilic compounds to aid in proteasome inhibition S Mukherjee, R Sparks, R Metcalf, W Brooks, K Daniel, WC Guida Bioorganic & medicinal chemistry letters 26 (15), 3826-3829, 2016 | 3 | 2016 |
| Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in hepatic stellate cells C Sun, C Zhou, K Daneshvar, AB Saad, AJ Kratkiewicz, BJ Toles, ... Hepatology, 10.1097, 2024 | 2 | 2024 |
| Regulation of Human Sortilin Alternative Splicing by Glucagon-like Peptide-1 (GLP1) in Adipocytes A Lui, RS Patel, M Krause-Hauch, RP Sparks, NA Patel International Journal of Molecular Sciences 24 (18), 14324, 2023 | 2 | 2023 |
| Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs C Sun, C Zhou, K Daneshvar, AB Saad, AJ Kratkiewicz, BJ Toles, ... Hepatology (Baltimore, Md.), 0 | 2 | |
