Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of CaV1.1 calcium channel ZZ Tang, V Yarotskyy, L Wei, K Sobczak, M Nakamori, K Eichinger, ... Human molecular genetics 21 (6), 1312-1324, 2012 | 197 | 2012 |
Transcript scanning reveals novel and extensive splice variations in human L-type voltage-gated calcium channel, Cav1. 2 α1 subunit ZZ Tang, MC Liang, S Lu, D Yu, CY Yu, DT Yue, TW Soong Journal of Biological Chemistry 279 (43), 44335-44343, 2004 | 194 | 2004 |
An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons JA Lee, ZZ Tang, DL Black Genes & development 23 (19), 2284-2293, 2009 | 178 | 2009 |
Smooth muscle-selective alternatively spliced exon generates functional variation in Cav1. 2 calcium channels P Liao, D Yu, S Lu, Z Tang, MC Liang, S Zeng, W Lin, TW Soong Journal of Biological Chemistry 279 (48), 50329-50335, 2004 | 116 | 2004 |
Identical de novo Mutation in the Type 1 Ryanodine Receptor Gene Associated with Fatal, Stress-induced Malignant Hyperthermia in Two Unrelated Families L Groom, SM Muldoon, ZZ Tang, BW Brandom, M Bayarsaikhan, S Bina, ... The Journal of the American Society of Anesthesiologists 115 (5), 938-945, 2011 | 105 | 2011 |
Developmental control of CaV1. 2 L-type calcium channel splicing by Fox proteins ZZ Tang, S Zheng, J Nikolic, DL Black Molecular and cellular biology, 2009 | 99 | 2009 |
Regulation of the mutually exclusive exons 8a and 8 in the CaV1. 2 calcium channel transcript by polypyrimidine tract-binding protein ZZ Tang, S Sharma, S Zheng, G Chawla, J Nikolic, DL Black Journal of Biological Chemistry 286 (12), 10007-10016, 2011 | 87 | 2011 |
Signature combinatorial splicing profiles of rat cardiac-and smooth-muscle Cav1. 2 channels with distinct biophysical properties ZZ Tang, X Hong, J Wang, TW Soong Cell calcium 41 (5), 417-428, 2007 | 61 | 2007 |
Differential splicing patterns of L-type calcium channel Cav1. 2 subunit in hearts of Spontaneously Hypertensive Rats and Wistar Kyoto Rats ZZ Tang, P Liao, G Li, FL Jiang, D Yu, X Hong, TF Yong, G Tan, S Lu, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (1), 118-130, 2008 | 53 | 2008 |
Features of modularly assembled compounds that impart bioactivity against an RNA target SG Rzuczek, Y Gao, ZZ Tang, CA Thornton, T Kodadek, MD Disney ACS chemical biology 8 (10), 2312-2321, 2013 | 46 | 2013 |
A small molecule that binds an RNA repeat expansion stimulates its decay via the exosome complex AJ Angelbello, RI Benhamou, SG Rzuczek, S Choudhary, Z Tang, ... Cell chemical biology 28 (1), 34-45. e6, 2021 | 29 | 2021 |
Targeted splice sequencing reveals RNA toxicity and therapeutic response in myotonic dystrophy MK Tanner, Z Tang, CA Thornton Nucleic acids research 49 (4), 2240-2254, 2021 | 21 | 2021 |
CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model A Ketley, M Wojciechowska, S Ghidelli-Disse, P Bamborough, TK Ghosh, ... Science Translational Medicine 12 (541), eaaz2415, 2020 | 18 | 2020 |
Detection of expanded RNA repeats using thermostable group II intron reverse transcriptase ST Carrell, Z Tang, S Mohr, AM Lambowitz, CA Thornton Nucleic Acids Research 46 (1), e1-e1, 2018 | 14 | 2018 |
Biophysical mechanisms for QRS-and QTc-interval prolongation in mice with cardiac expression of expanded CUG-repeat RNA KM Tylock, DS Auerbach, ZZ Tang, CA Thornton, RT Dirksen Journal of General Physiology 152 (2), e201912450, 2020 | 8 | 2020 |
An inducible change in Fox-1 JA Lee, ZZ Tang, DL Black A2BP1, 2009 | 5 | 2009 |
Transcript scanning reveals genetic diversity of human voltage calcium channel gene Ca (v) 1.2, generated by alterative splicing MC Liang, ZZ Tang, SQ Lu, DJ Yu, TF Yong, TW Soong JOURNAL OF NEUROCHEMISTRY 88, 41-41, 2004 | | 2004 |