| A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription K Ewan, B Pająk, M Stubbs, H Todd, O Barbeau, C Quevedo, H Botfield, ... Cancer research 70 (14), 5963-5973, 2010 | 122 | 2010 |
| DNA-dependent protein kinase (DNA-PK) inhibitors. Synthesis and biological activity of quinolin-4-one and pyridopyrimidin-4-one surrogates for the chromen-4-one chemotype C Cano, OR Barbeau, C Bailey, XL Cockcroft, NJ Curtin, H Duggan, ... Journal of medicinal chemistry 53 (24), 8498-8507, 2010 | 58 | 2010 |
| Synthesis of 2-trifluoromethyl-1, 3-oxazolidines as hydrolytically stable pseudoprolines G Chaume, O Barbeau, P Lesot, T Brigaud The Journal of Organic Chemistry 75 (12), 4135-4145, 2010 | 56 | 2010 |
| Endothelial angiogenesis and barrier function in response to thrombin require Ca2+ influx through the Na+/Ca2+ exchanger P Andrikopoulos, J Kieswich, SM Harwood, A Baba, T Matsuda, ... Journal of Biological Chemistry 290 (30), 18412-18428, 2015 | 51 | 2015 |
| Synthesis of terminally protected (S)-β3-H-DOPA by Arndt–Eistert homologation: An approach to crowned β-peptides A Gaucher, L Dutot, O Barbeau, W Hamchaoui, M Wakselman, ... Tetrahedron: Asymmetry 16 (4), 857-864, 2005 | 38 | 2005 |
| Quinolinone and pyridopyrimidinone inhibitors of DNA-dependent protein kinase OR Barbeau, C Cano-Soumillac, RJ Griffin, IR Hardcastle, GCM Smith, ... Organic & Biomolecular Chemistry 5 (16), 2670-2677, 2007 | 37 | 2007 |
| Exploiting protein conformational change to optimize adenosine-derived inhibitors of HSP70 MD Cheeseman, IM Westwood, O Barbeau, M Rowlands, S Dobson, ... Journal of Medicinal Chemistry 59 (10), 4625-4636, 2016 | 36 | 2016 |
| A general synthetic route to isomerically pure functionalized rhodamine dyes G Mudd, IP Pi, N Fethers, PG Dodd, OR Barbeau, M Auer Methods and Applications in Fluorescence 3 (4), 045002, 2015 | 29 | 2015 |
| Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa MD Ryan, AL Parkes, D Corbett, AP Dickie, M Southey, OA Andersen, ... Journal of Medicinal Chemistry 64 (19), 14377-14425, 2021 | 21 | 2021 |
| Synthesis of [18-C-6]-β3-(L)-DOPA, first β-amino acid with a crown-ether receptor side-chain A Gaucher, O Barbeau, W Hamchaoui, L Vandromme, K Wright, ... Tetrahedron letters 43 (46), 8241-8244, 2002 | 10 | 2002 |
| Targeting the PPM1D phenotype; 2, 4-bisarylthiazoles cause highly selective apoptosis in PPM1D amplified cell-lines MD Cheeseman, A Faisal, S Rayter, OR Barbeau, A Kalusa, M Westlake, ... Bioorganic & Medicinal Chemistry Letters 24 (15), 3469-3474, 2014 | 7 | 2014 |
| Synthesis of linear and cyclic homo-β-peptides based on a binaphthylic β-amino acid with only axial chirality A Gaucher, L Dutot, O Barbeau, M Wakselman, JP Mazaleyrat, C Peggion, ... Tetrahedron: Asymmetry 17 (1), 30-39, 2006 | 6 | 2006 |
| AI-driven discovery and profiling of GTAEXS-617, a selective and highly potent inhibitor of CDK7 J Besnard, J Joseph, H Bai, RA Paveley, T Wang, OR Barbeau, XH Gu, ... Cancer Research 82 (12_Supplement), 3930-3930, 2022 | 2 | 2022 |
| Facile Synthesis of a Next Generation Safety‐Catch Acid‐Labile Linker, SCAL‐2, Suitable for Solid‐Phase Synthesis, On‐Support Display and for Post‐Synthesis Tagging C Portal, M Hintersteiner, O Barbeau, P Dodd, M Huggett, I Pérez‐Pi, ... ChemistrySelect 2 (23), 6658-6662, 2017 | 2 | 2017 |
| Arylthioether acetamide and related compounds and their use in treating medical conditions MD Ryan, A Parkes, OR Barbeau, A Faulkner, M Holbrow-wilshaw, ... US Patent App. 18/275,880, 2024 | | 2024 |
| Aromatic heterocyclic compound, and pharmaceutical composition and application thereof X Gu, BAI Haiyun, OR Barbeau, J Besnard US Patent App. 18/257,959, 2024 | | 2024 |
| AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF X GU, H BAI, OR BARBEAU, J BESNARD EP Patent EP4,269,402, 2023 | | 2023 |
| Defining activity and patient selection of a novel CDK7 inhibitor, GTAEXS-617, through AI-supported primary cancer tissue profiling M Somlyay, E Durinikova, J Besnard, O Barbeau, J Le Coz, ... European Journal of Cancer 174, S44-S45, 2022 | | 2022 |
| Condensed heterocyclic compounds and their use K Jones, MD CHEESEMAN, S Linardopoulos, A FAISAL, OR BARBEAU, ... | | 2017 |
| Fused heterocyclic compounds and their use K Jones, MD Cheeseman, S Linardopoulos, A Faisal, OR Barbeau, ... US Patent 9,550,764, 2017 | | 2017 |
Ian Robert HardcastleNewcastle University在 ncl.ac.uk 的电子邮件经过验证
